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Mutant-selective Degradation by BRAF-targeting PROTACs
Shanique Alabi, Saul Jaime-Figueroa, Zhan Yao, Yijun Gao, John Hines, Kusal T.G. Samarasinghe, Lea Vogt, Neal Rosen, Craig M. Crews
doi: https://doi.org/10.1101/2020.08.10.245159
Shanique Alabi
1Department of Pharmacology, 333 Cedar Street, New Haven, CT, USA
Saul Jaime-Figueroa
2Molecular, Cellular, and Developmental Biology, Yale University, 260 Whitney Avenue, New Haven, CT, 06511, USA
Zhan Yao
3Program in Molecular Pharmacology, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
Yijun Gao
3Program in Molecular Pharmacology, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
John Hines
2Molecular, Cellular, and Developmental Biology, Yale University, 260 Whitney Avenue, New Haven, CT, 06511, USA
Kusal T.G. Samarasinghe
2Molecular, Cellular, and Developmental Biology, Yale University, 260 Whitney Avenue, New Haven, CT, 06511, USA
Lea Vogt
2Molecular, Cellular, and Developmental Biology, Yale University, 260 Whitney Avenue, New Haven, CT, 06511, USA
Neal Rosen
3Program in Molecular Pharmacology, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
Craig M. Crews
1Department of Pharmacology, 333 Cedar Street, New Haven, CT, USA
2Molecular, Cellular, and Developmental Biology, Yale University, 260 Whitney Avenue, New Haven, CT, 06511, USA
4Department of Chemistry, Yale University, 225 Prospect Street, New Haven CT, USA
Posted August 10, 2020.
Mutant-selective Degradation by BRAF-targeting PROTACs
Shanique Alabi, Saul Jaime-Figueroa, Zhan Yao, Yijun Gao, John Hines, Kusal T.G. Samarasinghe, Lea Vogt, Neal Rosen, Craig M. Crews
bioRxiv 2020.08.10.245159; doi: https://doi.org/10.1101/2020.08.10.245159
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