The specific features of the developing T cell compartment of the neonatal lung are a determinant of respiratory syncytial virus immunopathogenesis

Thomas Démoulins; Melanie Brügger; Beatrice Zumkehr; Blandina I. Oliveira Esteves; Kemal Mehinagic; Amal Fahmi; Loïc Borcard; Adriano Taddeo; Horst Posthaus; Charaf Benarafa; Nicolas Ruggli; Marco P. Alves

doi:10.1101/2020.08.14.250829

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The specific features of the developing T cell compartment of the neonatal lung are a determinant of respiratory syncytial virus immunopathogenesis

Thomas Démoulins, Melanie Brügger, Beatrice Zumkehr, Blandina I. Oliveira Esteves, Kemal Mehinagic, Amal Fahmi, Loïc Borcard, Adriano Taddeo, Horst Posthaus, Charaf Benarafa, Nicolas Ruggli, View ORCID ProfileMarco P. Alves

doi: https://doi.org/10.1101/2020.08.14.250829

Thomas Démoulins

1The Institute of Virology and Immunology, Mittelhäusern and Bern, Switzerland

2Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland

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Melanie Brügger

1The Institute of Virology and Immunology, Mittelhäusern and Bern, Switzerland

2Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland

3Graduate School for Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland

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Beatrice Zumkehr

1The Institute of Virology and Immunology, Mittelhäusern and Bern, Switzerland

2Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland

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Blandina I. Oliveira Esteves

1The Institute of Virology and Immunology, Mittelhäusern and Bern, Switzerland

2Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland

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Kemal Mehinagic

1The Institute of Virology and Immunology, Mittelhäusern and Bern, Switzerland

2Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland

3Graduate School for Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland

4Institute of Animal Pathology, Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland

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Amal Fahmi

1The Institute of Virology and Immunology, Mittelhäusern and Bern, Switzerland

2Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland

3Graduate School for Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland

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Loïc Borcard

1The Institute of Virology and Immunology, Mittelhäusern and Bern, Switzerland

2Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland

3Graduate School for Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland

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Adriano Taddeo

1The Institute of Virology and Immunology, Mittelhäusern and Bern, Switzerland

2Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland

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Horst Posthaus

4Institute of Animal Pathology, Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland

5COMPATH, Vetsuisse Faculty & Faculty of Medicine, University of Bern, Bern, Switzerland

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Charaf Benarafa

1The Institute of Virology and Immunology, Mittelhäusern and Bern, Switzerland

2Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland

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Nicolas Ruggli

1The Institute of Virology and Immunology, Mittelhäusern and Bern, Switzerland

2Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland

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Marco P. Alves

1The Institute of Virology and Immunology, Mittelhäusern and Bern, Switzerland

2Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland

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ORCID record for Marco P. Alves
For correspondence: marco.alves@vetsuisse.unibe.ch

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Posted October 23, 2020.

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The specific features of the developing T cell compartment of the neonatal lung are a determinant of respiratory syncytial virus immunopathogenesis

bioRxiv 2020.08.14.250829; doi: https://doi.org/10.1101/2020.08.14.250829

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The specific features of the developing T cell compartment of the neonatal lung are a determinant of respiratory syncytial virus immunopathogenesis

bioRxiv 2020.08.14.250829; doi: https://doi.org/10.1101/2020.08.14.250829

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