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Experimental infection of cattle with SARS-CoV-2

View ORCID ProfileLorenz Ulrich, View ORCID ProfileKerstin Wernike, Donata Hoffmann, Thomas C. Mettenleiter, View ORCID ProfileMartin Beer
doi: https://doi.org/10.1101/2020.08.25.254474
Lorenz Ulrich
Friedrich-Loeffler-Institut, Greifswald – Insel Riems, Germany
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  • ORCID record for Lorenz Ulrich
Kerstin Wernike
Friedrich-Loeffler-Institut, Greifswald – Insel Riems, Germany
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  • ORCID record for Kerstin Wernike
Donata Hoffmann
Friedrich-Loeffler-Institut, Greifswald – Insel Riems, Germany
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Thomas C. Mettenleiter
Friedrich-Loeffler-Institut, Greifswald – Insel Riems, Germany
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Martin Beer
Friedrich-Loeffler-Institut, Greifswald – Insel Riems, Germany
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  • ORCID record for Martin Beer
  • For correspondence: martin.beer@fli.de
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Abstract

Six cattle (Bos taurus) were intranasally inoculated with SARS-CoV-2 and kept together with three naïve in-contact animals. Low-level virus replication and a specific sero-reactivity were observed in two inoculated animals, despite the presence of high antibody titers against a bovine betacoronavirus. The in-contact animals did not become infected.

Competing Interest Statement

The authors have declared no competing interest.

Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.
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Posted August 25, 2020.
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Experimental infection of cattle with SARS-CoV-2
Lorenz Ulrich, Kerstin Wernike, Donata Hoffmann, Thomas C. Mettenleiter, Martin Beer
bioRxiv 2020.08.25.254474; doi: https://doi.org/10.1101/2020.08.25.254474
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Experimental infection of cattle with SARS-CoV-2
Lorenz Ulrich, Kerstin Wernike, Donata Hoffmann, Thomas C. Mettenleiter, Martin Beer
bioRxiv 2020.08.25.254474; doi: https://doi.org/10.1101/2020.08.25.254474

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