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A dual mechanism of enhancer activation by FOXA pioneer factors induces endodermal organ fates
View ORCID ProfileRyan J. Geusz, Allen Wang, Dieter K. Lam, Nicholas K. Vinckier, Konstantinos-Dionysios Alysandratos, David A. Roberts, View ORCID ProfileJinzhao Wang, View ORCID ProfileSamy Kefalopoulou, View ORCID ProfileYunjiang Qiu, View ORCID ProfileJoshua Chiou, View ORCID ProfileKyle J. Gaulton, View ORCID ProfileBing Ren, Darrel N. Kotton, View ORCID ProfileMaike Sander
doi: https://doi.org/10.1101/2020.08.28.263020
Ryan J. Geusz
1Department of Pediatrics, Pediatric Diabetes Research Center, University of California, San Diego, La Jolla, CA 92093, USA
2Department of Cellular & Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA
3Sanford Consortium for Regenerative Medicine, San Diego, La Jolla, CA 92093, USA
4Biomedical Graduate Studies Program, University of California San Diego, La Jolla CA, 92037, USA
Allen Wang
1Department of Pediatrics, Pediatric Diabetes Research Center, University of California, San Diego, La Jolla, CA 92093, USA
2Department of Cellular & Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA
3Sanford Consortium for Regenerative Medicine, San Diego, La Jolla, CA 92093, USA
Dieter K. Lam
1Department of Pediatrics, Pediatric Diabetes Research Center, University of California, San Diego, La Jolla, CA 92093, USA
2Department of Cellular & Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA
3Sanford Consortium for Regenerative Medicine, San Diego, La Jolla, CA 92093, USA
Nicholas K. Vinckier
1Department of Pediatrics, Pediatric Diabetes Research Center, University of California, San Diego, La Jolla, CA 92093, USA
2Department of Cellular & Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA
3Sanford Consortium for Regenerative Medicine, San Diego, La Jolla, CA 92093, USA
Konstantinos-Dionysios Alysandratos
6Center for Regenerative Medicine of Boston University and Boston Medical Center, Boston, MA 02118, USA
7The Pulmonary Center and Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA
David A. Roberts
6Center for Regenerative Medicine of Boston University and Boston Medical Center, Boston, MA 02118, USA
Jinzhao Wang
1Department of Pediatrics, Pediatric Diabetes Research Center, University of California, San Diego, La Jolla, CA 92093, USA
2Department of Cellular & Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA
3Sanford Consortium for Regenerative Medicine, San Diego, La Jolla, CA 92093, USA
Samy Kefalopoulou
1Department of Pediatrics, Pediatric Diabetes Research Center, University of California, San Diego, La Jolla, CA 92093, USA
2Department of Cellular & Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA
3Sanford Consortium for Regenerative Medicine, San Diego, La Jolla, CA 92093, USA
Yunjiang Qiu
2Department of Cellular & Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA
Joshua Chiou
1Department of Pediatrics, Pediatric Diabetes Research Center, University of California, San Diego, La Jolla, CA 92093, USA
4Biomedical Graduate Studies Program, University of California San Diego, La Jolla CA, 92037, USA
Kyle J. Gaulton
1Department of Pediatrics, Pediatric Diabetes Research Center, University of California, San Diego, La Jolla, CA 92093, USA
Bing Ren
2Department of Cellular & Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA
5Ludwig Institute for Cancer Research, La Jolla, CA 92093-0653, USA
Darrel N. Kotton
6Center for Regenerative Medicine of Boston University and Boston Medical Center, Boston, MA 02118, USA
7The Pulmonary Center and Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA
Maike Sander
1Department of Pediatrics, Pediatric Diabetes Research Center, University of California, San Diego, La Jolla, CA 92093, USA
2Department of Cellular & Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA
3Sanford Consortium for Regenerative Medicine, San Diego, La Jolla, CA 92093, USA
Article usage
Posted August 29, 2020.
A dual mechanism of enhancer activation by FOXA pioneer factors induces endodermal organ fates
Ryan J. Geusz, Allen Wang, Dieter K. Lam, Nicholas K. Vinckier, Konstantinos-Dionysios Alysandratos, David A. Roberts, Jinzhao Wang, Samy Kefalopoulou, Yunjiang Qiu, Joshua Chiou, Kyle J. Gaulton, Bing Ren, Darrel N. Kotton, Maike Sander
bioRxiv 2020.08.28.263020; doi: https://doi.org/10.1101/2020.08.28.263020
A dual mechanism of enhancer activation by FOXA pioneer factors induces endodermal organ fates
Ryan J. Geusz, Allen Wang, Dieter K. Lam, Nicholas K. Vinckier, Konstantinos-Dionysios Alysandratos, David A. Roberts, Jinzhao Wang, Samy Kefalopoulou, Yunjiang Qiu, Joshua Chiou, Kyle J. Gaulton, Bing Ren, Darrel N. Kotton, Maike Sander
bioRxiv 2020.08.28.263020; doi: https://doi.org/10.1101/2020.08.28.263020
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