New Results
A simplified cell-based assay to identify coronavirus 3CL protease inhibitors
Samuel J. Resnick, Sho Iketani, Seo Jung Hong, Arie Zask, Hengrui Liu, Sungsoo Kim, Schuyler Melore, Manoj S. Nair, Yaoxing Huang, Nicholas E.S. Tay, Tomislav Rovis, Hee Won Yang, View ORCID ProfileBrent R. Stockwell, David D. Ho, Alejandro Chavez
doi: https://doi.org/10.1101/2020.08.29.272864
Samuel J. Resnick
1Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, 10032, USA
2Medical Scientist Training Program, Columbia University Irving Medical Center, New York, NY, 10032, USA
Sho Iketani
3Aaron Diamond AIDS Research Center, Columbia University Irving Medical Center, New York, NY, 10032, USA
4Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, 10032, USA
Seo Jung Hong
1Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, 10032, USA
Arie Zask
5Department of Biological Sciences, Columbia University, New York, NY, 10027, USA
Hengrui Liu
6Department of Chemistry, Columbia University, New York, NY, 10027, USA
Sungsoo Kim
1Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, 10032, USA
Schuyler Melore
1Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, 10032, USA
Manoj S. Nair
3Aaron Diamond AIDS Research Center, Columbia University Irving Medical Center, New York, NY, 10032, USA
Yaoxing Huang
3Aaron Diamond AIDS Research Center, Columbia University Irving Medical Center, New York, NY, 10032, USA
Nicholas E.S. Tay
6Department of Chemistry, Columbia University, New York, NY, 10027, USA
Tomislav Rovis
6Department of Chemistry, Columbia University, New York, NY, 10027, USA
Hee Won Yang
1Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, 10032, USA
Brent R. Stockwell
5Department of Biological Sciences, Columbia University, New York, NY, 10027, USA
6Department of Chemistry, Columbia University, New York, NY, 10027, USA
David D. Ho
3Aaron Diamond AIDS Research Center, Columbia University Irving Medical Center, New York, NY, 10032, USA
Alejandro Chavez
1Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, 10032, USA
Posted August 29, 2020.
A simplified cell-based assay to identify coronavirus 3CL protease inhibitors
Samuel J. Resnick, Sho Iketani, Seo Jung Hong, Arie Zask, Hengrui Liu, Sungsoo Kim, Schuyler Melore, Manoj S. Nair, Yaoxing Huang, Nicholas E.S. Tay, Tomislav Rovis, Hee Won Yang, Brent R. Stockwell, David D. Ho, Alejandro Chavez
bioRxiv 2020.08.29.272864; doi: https://doi.org/10.1101/2020.08.29.272864
A simplified cell-based assay to identify coronavirus 3CL protease inhibitors
Samuel J. Resnick, Sho Iketani, Seo Jung Hong, Arie Zask, Hengrui Liu, Sungsoo Kim, Schuyler Melore, Manoj S. Nair, Yaoxing Huang, Nicholas E.S. Tay, Tomislav Rovis, Hee Won Yang, Brent R. Stockwell, David D. Ho, Alejandro Chavez
bioRxiv 2020.08.29.272864; doi: https://doi.org/10.1101/2020.08.29.272864
Subject Area
Subject Areas
- Biochemistry (11715)
- Bioengineering (8723)
- Bioinformatics (29128)
- Biophysics (14935)
- Cancer Biology (12049)
- Cell Biology (17359)
- Clinical Trials (138)
- Developmental Biology (9406)
- Ecology (14144)
- Epidemiology (2067)
- Evolutionary Biology (18268)
- Genetics (12221)
- Genomics (16767)
- Immunology (11843)
- Microbiology (28014)
- Molecular Biology (11560)
- Neuroscience (60810)
- Paleontology (450)
- Pathology (1864)
- Pharmacology and Toxicology (3231)
- Physiology (4940)
- Plant Biology (10384)
- Synthetic Biology (2878)
- Systems Biology (7333)
- Zoology (1642)