New Results
A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses
View ORCID ProfileTiong Kit Tan, View ORCID ProfilePramila Rijal, View ORCID ProfileRolle Rahikainen, Anthony H. Keeble, Lisa Schimanski, Saira Hussain, View ORCID ProfileRuth Harvey, View ORCID ProfileJack W.P. Hayes, Jane. C. Edwards, View ORCID ProfileRebecca K. McLean, View ORCID ProfileVeronica Martini, View ORCID ProfileMiriam Pedrera, Nazia Thakur, Carina Conceicao, View ORCID ProfileIsabelle Dietrich, Holly Shelton, Anna Ludi, Ginette Wilsden, Clare Browning, Adrian K. Zagrajek, Dagmara Bialy, View ORCID ProfileSushant Bhat, Phoebe Stevenson-Leggett, Philippa Hollinghurst, Matthew Tully, View ORCID ProfileKaty Moffat, Chris Chiu, View ORCID ProfileRyan Waters, Ashley Gray, Mehreen Azhar, Valerie Mioulet, Joseph Newman, Amin S. Asfor, Alison Burman, Sylvia Crossley, John A. Hammond, Elma Tchilian, View ORCID ProfileBryan Charleston, Dalan Bailey, Tobias J. Tuthill, View ORCID ProfileSimon P. Graham, View ORCID ProfileTomas Malinauskas, View ORCID ProfileJiandong Huo, Julia A. Tree, Karen R. Buttigieg, View ORCID ProfileRaymond J. Owens, Miles W. Caroll, View ORCID ProfileRodney S. Daniels, John W. McCauley, Kuan-Ying A. Huang, View ORCID ProfileMark Howarth, View ORCID ProfileAlain R. Townsend
doi: https://doi.org/10.1101/2020.08.31.275701
Tiong Kit Tan
1MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DS, UK
Pramila Rijal
1MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DS, UK
2Centre for Translational Immunology, Chinese Academy of Medical Sciences Oxford Institute, University of Oxford, Oxford, UK
Rolle Rahikainen
3Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK
Anthony H. Keeble
3Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK
Lisa Schimanski
1MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DS, UK
2Centre for Translational Immunology, Chinese Academy of Medical Sciences Oxford Institute, University of Oxford, Oxford, UK
Saira Hussain
6Worldwide Influenza Centre, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK
Ruth Harvey
6Worldwide Influenza Centre, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK
Jack W.P. Hayes
4The Pirbright Institute, Ash Road, Pirbright GU24 0NF, UK
Jane. C. Edwards
4The Pirbright Institute, Ash Road, Pirbright GU24 0NF, UK
Rebecca K. McLean
4The Pirbright Institute, Ash Road, Pirbright GU24 0NF, UK
Veronica Martini
4The Pirbright Institute, Ash Road, Pirbright GU24 0NF, UK
Miriam Pedrera
4The Pirbright Institute, Ash Road, Pirbright GU24 0NF, UK
Nazia Thakur
4The Pirbright Institute, Ash Road, Pirbright GU24 0NF, UK
Carina Conceicao
4The Pirbright Institute, Ash Road, Pirbright GU24 0NF, UK
Isabelle Dietrich
4The Pirbright Institute, Ash Road, Pirbright GU24 0NF, UK
Holly Shelton
4The Pirbright Institute, Ash Road, Pirbright GU24 0NF, UK
Anna Ludi
4The Pirbright Institute, Ash Road, Pirbright GU24 0NF, UK
Ginette Wilsden
4The Pirbright Institute, Ash Road, Pirbright GU24 0NF, UK
Clare Browning
4The Pirbright Institute, Ash Road, Pirbright GU24 0NF, UK
Adrian K. Zagrajek
4The Pirbright Institute, Ash Road, Pirbright GU24 0NF, UK
Dagmara Bialy
4The Pirbright Institute, Ash Road, Pirbright GU24 0NF, UK
Sushant Bhat
4The Pirbright Institute, Ash Road, Pirbright GU24 0NF, UK
Phoebe Stevenson-Leggett
4The Pirbright Institute, Ash Road, Pirbright GU24 0NF, UK
Philippa Hollinghurst
4The Pirbright Institute, Ash Road, Pirbright GU24 0NF, UK
5Department of Microbial Sciences, Faculty of Health and Medical Sciences, University of Surrey, Guildford, GU2 7XH, UK
Matthew Tully
4The Pirbright Institute, Ash Road, Pirbright GU24 0NF, UK
Katy Moffat
4The Pirbright Institute, Ash Road, Pirbright GU24 0NF, UK
Chris Chiu
4The Pirbright Institute, Ash Road, Pirbright GU24 0NF, UK
Ryan Waters
4The Pirbright Institute, Ash Road, Pirbright GU24 0NF, UK
Ashley Gray
4The Pirbright Institute, Ash Road, Pirbright GU24 0NF, UK
Mehreen Azhar
4The Pirbright Institute, Ash Road, Pirbright GU24 0NF, UK
Valerie Mioulet
4The Pirbright Institute, Ash Road, Pirbright GU24 0NF, UK
Joseph Newman
4The Pirbright Institute, Ash Road, Pirbright GU24 0NF, UK
Amin S. Asfor
4The Pirbright Institute, Ash Road, Pirbright GU24 0NF, UK
Alison Burman
4The Pirbright Institute, Ash Road, Pirbright GU24 0NF, UK
Sylvia Crossley
4The Pirbright Institute, Ash Road, Pirbright GU24 0NF, UK
John A. Hammond
4The Pirbright Institute, Ash Road, Pirbright GU24 0NF, UK
Elma Tchilian
4The Pirbright Institute, Ash Road, Pirbright GU24 0NF, UK
Bryan Charleston
4The Pirbright Institute, Ash Road, Pirbright GU24 0NF, UK
Dalan Bailey
4The Pirbright Institute, Ash Road, Pirbright GU24 0NF, UK
Tobias J. Tuthill
4The Pirbright Institute, Ash Road, Pirbright GU24 0NF, UK
Simon P. Graham
4The Pirbright Institute, Ash Road, Pirbright GU24 0NF, UK
Tomas Malinauskas
8Division of Structural Biology, Henry Wellcome Building for Genomic Medicine, University of Oxford, Oxford, OX3 7BN, UK
Jiandong Huo
7Protein Production UK, Research Complex at Harwell, and Rosalind Franklin Institute, Rutherford Appleton Laboratory, Harwell, Didcot, OX11 0FA, UK
8Division of Structural Biology, Henry Wellcome Building for Genomic Medicine, University of Oxford, Oxford, OX3 7BN, UK
Julia A. Tree
9National Infection Service, Public Health England, Porton Down, Salisbury, SP4 0JG, UK
Karen R. Buttigieg
9National Infection Service, Public Health England, Porton Down, Salisbury, SP4 0JG, UK
Raymond J. Owens
7Protein Production UK, Research Complex at Harwell, and Rosalind Franklin Institute, Rutherford Appleton Laboratory, Harwell, Didcot, OX11 0FA, UK
8Division of Structural Biology, Henry Wellcome Building for Genomic Medicine, University of Oxford, Oxford, OX3 7BN, UK
Miles W. Caroll
9National Infection Service, Public Health England, Porton Down, Salisbury, SP4 0JG, UK
10Nufflield Department of Medicine, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK
Rodney S. Daniels
6Worldwide Influenza Centre, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK
John W. McCauley
6Worldwide Influenza Centre, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK
Kuan-Ying A. Huang
11Research Center for Emerging Viral Infections, College of Medicine, Chang Gung University, Taoyuan, Taiwan
12Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Memorial Hospital, Taoyuan, Taiwan
Mark Howarth
3Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK
Alain R. Townsend
1MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DS, UK
2Centre for Translational Immunology, Chinese Academy of Medical Sciences Oxford Institute, University of Oxford, Oxford, UK
Posted August 31, 2020.
A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses
Tiong Kit Tan, Pramila Rijal, Rolle Rahikainen, Anthony H. Keeble, Lisa Schimanski, Saira Hussain, Ruth Harvey, Jack W.P. Hayes, Jane. C. Edwards, Rebecca K. McLean, Veronica Martini, Miriam Pedrera, Nazia Thakur, Carina Conceicao, Isabelle Dietrich, Holly Shelton, Anna Ludi, Ginette Wilsden, Clare Browning, Adrian K. Zagrajek, Dagmara Bialy, Sushant Bhat, Phoebe Stevenson-Leggett, Philippa Hollinghurst, Matthew Tully, Katy Moffat, Chris Chiu, Ryan Waters, Ashley Gray, Mehreen Azhar, Valerie Mioulet, Joseph Newman, Amin S. Asfor, Alison Burman, Sylvia Crossley, John A. Hammond, Elma Tchilian, Bryan Charleston, Dalan Bailey, Tobias J. Tuthill, Simon P. Graham, Tomas Malinauskas, Jiandong Huo, Julia A. Tree, Karen R. Buttigieg, Raymond J. Owens, Miles W. Caroll, Rodney S. Daniels, John W. McCauley, Kuan-Ying A. Huang, Mark Howarth, Alain R. Townsend
bioRxiv 2020.08.31.275701; doi: https://doi.org/10.1101/2020.08.31.275701
A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses
Tiong Kit Tan, Pramila Rijal, Rolle Rahikainen, Anthony H. Keeble, Lisa Schimanski, Saira Hussain, Ruth Harvey, Jack W.P. Hayes, Jane. C. Edwards, Rebecca K. McLean, Veronica Martini, Miriam Pedrera, Nazia Thakur, Carina Conceicao, Isabelle Dietrich, Holly Shelton, Anna Ludi, Ginette Wilsden, Clare Browning, Adrian K. Zagrajek, Dagmara Bialy, Sushant Bhat, Phoebe Stevenson-Leggett, Philippa Hollinghurst, Matthew Tully, Katy Moffat, Chris Chiu, Ryan Waters, Ashley Gray, Mehreen Azhar, Valerie Mioulet, Joseph Newman, Amin S. Asfor, Alison Burman, Sylvia Crossley, John A. Hammond, Elma Tchilian, Bryan Charleston, Dalan Bailey, Tobias J. Tuthill, Simon P. Graham, Tomas Malinauskas, Jiandong Huo, Julia A. Tree, Karen R. Buttigieg, Raymond J. Owens, Miles W. Caroll, Rodney S. Daniels, John W. McCauley, Kuan-Ying A. Huang, Mark Howarth, Alain R. Townsend
bioRxiv 2020.08.31.275701; doi: https://doi.org/10.1101/2020.08.31.275701
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