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Reduction of a Stochastic Model of Gene Expression: Lagrangian Dynamics Gives Access to Basins of Attraction as Cell Types and Metastabilty

View ORCID ProfileElias Ventre, View ORCID ProfileThibault Espinasse, View ORCID ProfileCharles-Edouard Bréhier, View ORCID ProfileVincent Calvez, View ORCID ProfileThomas Lepoutre, View ORCID ProfileOlivier Gandrillon
doi: https://doi.org/10.1101/2020.09.04.283176
Elias Ventre
1Univ Lyon, ENS de Lyon, Univ Claude Bernard, CNRS UMR 5239, INSERM U1210, Laboratory of Biology and Modelling of the Cell, 46 allée d’Italie, Site Jacques Monod, F-69007 Lyon, France
2Inria Team Dracula, Inria Center Grenoble Rhone-Alpes, Grenoble, France
3Univ Lyon, Université Claude Bernard Lyon 1, CNRS UMR 5208, Institut Camille Jordan, 43 blvd du 11 novembre 1918, F-6962 Villeurbanne, France
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  • ORCID record for Elias Ventre
  • For correspondence: elias.ventre@ens-lyon.fr
Thibault Espinasse
2Inria Team Dracula, Inria Center Grenoble Rhone-Alpes, Grenoble, France
3Univ Lyon, Université Claude Bernard Lyon 1, CNRS UMR 5208, Institut Camille Jordan, 43 blvd du 11 novembre 1918, F-6962 Villeurbanne, France
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Charles-Edouard Bréhier
3Univ Lyon, Université Claude Bernard Lyon 1, CNRS UMR 5208, Institut Camille Jordan, 43 blvd du 11 novembre 1918, F-6962 Villeurbanne, France
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Vincent Calvez
2Inria Team Dracula, Inria Center Grenoble Rhone-Alpes, Grenoble, France
3Univ Lyon, Université Claude Bernard Lyon 1, CNRS UMR 5208, Institut Camille Jordan, 43 blvd du 11 novembre 1918, F-6962 Villeurbanne, France
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Thomas Lepoutre
2Inria Team Dracula, Inria Center Grenoble Rhone-Alpes, Grenoble, France
3Univ Lyon, Université Claude Bernard Lyon 1, CNRS UMR 5208, Institut Camille Jordan, 43 blvd du 11 novembre 1918, F-6962 Villeurbanne, France
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Olivier Gandrillon
1Univ Lyon, ENS de Lyon, Univ Claude Bernard, CNRS UMR 5239, INSERM U1210, Laboratory of Biology and Modelling of the Cell, 46 allée d’Italie, Site Jacques Monod, F-69007 Lyon, France
2Inria Team Dracula, Inria Center Grenoble Rhone-Alpes, Grenoble, France
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  • ORCID record for Olivier Gandrillon
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Article Information

doi 
https://doi.org/10.1101/2020.09.04.283176
History 
  • October 1, 2021.

Article Versions

  • Version 1 (September 5, 2020 - 21:37).
  • Version 2 (September 7, 2020 - 20:31).
  • Version 3 (March 15, 2021 - 04:54).
  • You are currently viewing Version 4 of this article (October 1, 2021 - 04:17).
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Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC 4.0 International license.

Author Information

  1. Elias Ventre1,2,3,*,
  2. Thibault Espinasse2,3,
  3. Charles-Edouard Bréhier3,
  4. Vincent Calvez2,3,
  5. Thomas Lepoutre2,3 and
  6. Olivier Gandrillon1,2
  1. 1Univ Lyon, ENS de Lyon, Univ Claude Bernard, CNRS UMR 5239, INSERM U1210, Laboratory of Biology and Modelling of the Cell, 46 allée d’Italie, Site Jacques Monod, F-69007 Lyon, France
  2. 2Inria Team Dracula, Inria Center Grenoble Rhone-Alpes, Grenoble, France
  3. 3Univ Lyon, Université Claude Bernard Lyon 1, CNRS UMR 5208, Institut Camille Jordan, 43 blvd du 11 novembre 1918, F-6962 Villeurbanne, France
  1. ↵*Corresponding author: Elias Ventre - elias.ventre{at}ens-lyon.fr.
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Reduction of a Stochastic Model of Gene Expression: Lagrangian Dynamics Gives Access to Basins of Attraction as Cell Types and Metastabilty
Elias Ventre, Thibault Espinasse, Charles-Edouard Bréhier, Vincent Calvez, Thomas Lepoutre, Olivier Gandrillon
bioRxiv 2020.09.04.283176; doi: https://doi.org/10.1101/2020.09.04.283176
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Reduction of a Stochastic Model of Gene Expression: Lagrangian Dynamics Gives Access to Basins of Attraction as Cell Types and Metastabilty
Elias Ventre, Thibault Espinasse, Charles-Edouard Bréhier, Vincent Calvez, Thomas Lepoutre, Olivier Gandrillon
bioRxiv 2020.09.04.283176; doi: https://doi.org/10.1101/2020.09.04.283176

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