The Anti-histamine Azelastine, Identified by Computational Drug Repurposing, Inhibits SARS-CoV-2 Infection in Reconstituted Human Nasal Tissue In Vitro

Robert Konrat; Henrietta Papp; Valéria Szijártó; Tanja Gesell; Gábor Nagy; Mónika Madai; Safia Zeghbib; Anett Kuczmog; Zsófia Lanszki; Zsuzsanna Helyes; Gábor Kemenesi; Ferenc Jakab; Eszter Nagy

doi:10.1101/2020.09.15.296228

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The Anti-histamine Azelastine, Identified by Computational Drug Repurposing, Inhibits SARS-CoV-2 Infection in Reconstituted Human Nasal Tissue In Vitro

View ORCID ProfileRobert Konrat, Henrietta Papp, Valéria Szijártó, Tanja Gesell, Gábor Nagy, Mónika Madai, Safia Zeghbib, Anett Kuczmog, Zsófia Lanszki, Zsuzsanna Helyes, Gábor Kemenesi, Ferenc Jakab, Eszter Nagy

doi: https://doi.org/10.1101/2020.09.15.296228

Robert Konrat

aDepartment of Structural and Computational Biology, Max F. Perutz Laboratories, University of Vienna, Vienna Biocenter Campus 5, A-1030 Vienna, Austria

bCalyxha Biotechnologies GmbH, Karl-Farkas-Gasse 22, A-1030 Vienna, Austria

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ORCID record for Robert Konrat
For correspondence: robert.konrat@univie.ac.at eszter.nagy@cebina.eu

Henrietta Papp

cNational Laboratory of Virology, Szentágothai Research Centre, University of Pécs, Pécs, Hungary

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Valéria Szijártó

dCEBINA (Central European Biotech Incubator and Accelerator) GmbH, Karl-Farkas-Gasse 22, A-1030 Vienna, Austria

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Tanja Gesell

bCalyxha Biotechnologies GmbH, Karl-Farkas-Gasse 22, A-1030 Vienna, Austria

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Gábor Nagy

dCEBINA (Central European Biotech Incubator and Accelerator) GmbH, Karl-Farkas-Gasse 22, A-1030 Vienna, Austria

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Mónika Madai

cNational Laboratory of Virology, Szentágothai Research Centre, University of Pécs, Pécs, Hungary

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Safia Zeghbib

cNational Laboratory of Virology, Szentágothai Research Centre, University of Pécs, Pécs, Hungary

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Anett Kuczmog

cNational Laboratory of Virology, Szentágothai Research Centre, University of Pécs, Pécs, Hungary

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Zsófia Lanszki

cNational Laboratory of Virology, Szentágothai Research Centre, University of Pécs, Pécs, Hungary

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Zsuzsanna Helyes

eDepartment of Pharmacology and Pharmacotherapy, Medical School & Szentágothai Research Center, University of Pécs, Pécs, Hungary

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Gábor Kemenesi

cNational Laboratory of Virology, Szentágothai Research Centre, University of Pécs, Pécs, Hungary

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Ferenc Jakab

cNational Laboratory of Virology, Szentágothai Research Centre, University of Pécs, Pécs, Hungary

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Eszter Nagy

bCalyxha Biotechnologies GmbH, Karl-Farkas-Gasse 22, A-1030 Vienna, Austria

dCEBINA (Central European Biotech Incubator and Accelerator) GmbH, Karl-Farkas-Gasse 22, A-1030 Vienna, Austria

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For correspondence: robert.konrat@univie.ac.at eszter.nagy@cebina.eu

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The Anti-histamine Azelastine, Identified by Computational Drug Repurposing, Inhibits SARS-CoV-2 Infection in Reconstituted Human Nasal Tissue In Vitro

Robert Konrat, Henrietta Papp, Valéria Szijártó, Tanja Gesell, Gábor Nagy, Mónika Madai, Safia Zeghbib, Anett Kuczmog, Zsófia Lanszki, Zsuzsanna Helyes, Gábor Kemenesi, Ferenc Jakab, Eszter Nagy

bioRxiv 2020.09.15.296228; doi: https://doi.org/10.1101/2020.09.15.296228

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The Anti-histamine Azelastine, Identified by Computational Drug Repurposing, Inhibits SARS-CoV-2 Infection in Reconstituted Human Nasal Tissue In Vitro

bioRxiv 2020.09.15.296228; doi: https://doi.org/10.1101/2020.09.15.296228

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