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Elicitation of potent serum neutralizing antibody responses in rabbits by immunization with an HIV-1 clade C trimeric Env derived from an Indian elite neutralizer
Rajesh Kumar, Suprit Deshpande, View ORCID ProfileLeigh M. Sewall, View ORCID ProfileGabriel Ozorowski, Christopher A. Cottrell, View ORCID ProfileWen-Hsin Lee, View ORCID ProfileLauren G. Holden, View ORCID ProfileSara T. Richey, View ORCID ProfileAntra Singh Chandrawacar, Kanika Dhiman, Ashish, Vivek Kumar, View ORCID ProfileShubbir Ahmed, Nitin Hingankar, Naresh Kumar, Kailapuri G Murugavel, Aylur K Srikrishnan, View ORCID ProfileDevin Sok, View ORCID ProfileAndrew B. Ward, View ORCID ProfileJayanta Bhattacharya
doi: https://doi.org/10.1101/2020.09.15.297697
Rajesh Kumar
1Translational Health Science & Technology Institute, NCR Biotech Science Cluster, Faridabad, Haryana-121001, India
Suprit Deshpande
1Translational Health Science & Technology Institute, NCR Biotech Science Cluster, Faridabad, Haryana-121001, India
Leigh M. Sewall
2Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA; Scripps Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA 92037, USA; IAVI Neutralizing Antibody Center and the Collaboration for AIDS Vaccine Discovery (CAVD), The Scripps Research Institute, La Jolla, CA 92037, USA
Gabriel Ozorowski
2Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA; Scripps Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA 92037, USA; IAVI Neutralizing Antibody Center and the Collaboration for AIDS Vaccine Discovery (CAVD), The Scripps Research Institute, La Jolla, CA 92037, USA
Christopher A. Cottrell
2Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA; Scripps Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA 92037, USA; IAVI Neutralizing Antibody Center and the Collaboration for AIDS Vaccine Discovery (CAVD), The Scripps Research Institute, La Jolla, CA 92037, USA
Wen-Hsin Lee
2Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA; Scripps Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA 92037, USA; IAVI Neutralizing Antibody Center and the Collaboration for AIDS Vaccine Discovery (CAVD), The Scripps Research Institute, La Jolla, CA 92037, USA
Lauren G. Holden
2Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA; Scripps Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA 92037, USA; IAVI Neutralizing Antibody Center and the Collaboration for AIDS Vaccine Discovery (CAVD), The Scripps Research Institute, La Jolla, CA 92037, USA
Sara T. Richey
2Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA; Scripps Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA 92037, USA; IAVI Neutralizing Antibody Center and the Collaboration for AIDS Vaccine Discovery (CAVD), The Scripps Research Institute, La Jolla, CA 92037, USA
Antra Singh Chandrawacar
3CSIR-Institute of Microbial Technology (IMTECH), Chandigarh 160036
4Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002
Kanika Dhiman
3CSIR-Institute of Microbial Technology (IMTECH), Chandigarh 160036
Ashish
3CSIR-Institute of Microbial Technology (IMTECH), Chandigarh 160036
4Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002
Vivek Kumar
1Translational Health Science & Technology Institute, NCR Biotech Science Cluster, Faridabad, Haryana-121001, India
Shubbir Ahmed
Nitin Hingankar
1Translational Health Science & Technology Institute, NCR Biotech Science Cluster, Faridabad, Haryana-121001, India
Naresh Kumar
Kailapuri G Murugavel
5Y. R. Gaitonde Centre for AIDS Research and Education, YRG CARE Laboratory, Rajiv Gandhi Salai, Adyar, Chennai-600113, Chennai, India, 600113
Aylur K Srikrishnan
5Y. R. Gaitonde Centre for AIDS Research and Education, YRG CARE Laboratory, Rajiv Gandhi Salai, Adyar, Chennai-600113, Chennai, India, 600113
Devin Sok
6IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA 92037, USA; International AIDS Vaccine Initiative (IAVI), New York, NY10004, USA
Andrew B. Ward
2Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA; Scripps Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA 92037, USA; IAVI Neutralizing Antibody Center and the Collaboration for AIDS Vaccine Discovery (CAVD), The Scripps Research Institute, La Jolla, CA 92037, USA
Jayanta Bhattacharya
1Translational Health Science & Technology Institute, NCR Biotech Science Cluster, Faridabad, Haryana-121001, India
7International AIDS Vaccine Initiative, New Delhi - 110029, India; International AIDS Vaccine Initiative, New York, NY 10004, USA
Article usage
Posted September 15, 2020.
Elicitation of potent serum neutralizing antibody responses in rabbits by immunization with an HIV-1 clade C trimeric Env derived from an Indian elite neutralizer
Rajesh Kumar, Suprit Deshpande, Leigh M. Sewall, Gabriel Ozorowski, Christopher A. Cottrell, Wen-Hsin Lee, Lauren G. Holden, Sara T. Richey, Antra Singh Chandrawacar, Kanika Dhiman, Ashish, Vivek Kumar, Shubbir Ahmed, Nitin Hingankar, Naresh Kumar, Kailapuri G Murugavel, Aylur K Srikrishnan, Devin Sok, Andrew B. Ward, Jayanta Bhattacharya
bioRxiv 2020.09.15.297697; doi: https://doi.org/10.1101/2020.09.15.297697
Elicitation of potent serum neutralizing antibody responses in rabbits by immunization with an HIV-1 clade C trimeric Env derived from an Indian elite neutralizer
Rajesh Kumar, Suprit Deshpande, Leigh M. Sewall, Gabriel Ozorowski, Christopher A. Cottrell, Wen-Hsin Lee, Lauren G. Holden, Sara T. Richey, Antra Singh Chandrawacar, Kanika Dhiman, Ashish, Vivek Kumar, Shubbir Ahmed, Nitin Hingankar, Naresh Kumar, Kailapuri G Murugavel, Aylur K Srikrishnan, Devin Sok, Andrew B. Ward, Jayanta Bhattacharya
bioRxiv 2020.09.15.297697; doi: https://doi.org/10.1101/2020.09.15.297697
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