Baseline T cell immune phenotypes predict virologic and disease control upon SARS-CoV infection

Jessica B. Graham; Jessica L. Swarts; Sarah R. Leist; Alexandra Schäfer; Vineet D. Menachery; Lisa E. Gralinski; Sophia Jeng; Darla R. Miller; Michael A. Mooney; Shannon K. McWeeney; Martin T. Ferris; Fernando Pardo-Manuel de Villena; Mark T. Heise; Ralph S. Baric; Jennifer M. Lund

doi:10.1101/2020.09.21.306837

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Baseline T cell immune phenotypes predict virologic and disease control upon SARS-CoV infection

Jessica B. Graham, Jessica L. Swarts, Sarah R. Leist, Alexandra Schäfer, Vineet D. Menachery, Lisa E. Gralinski, Sophia Jeng, Darla R. Miller, Michael A. Mooney, Shannon K. McWeeney, Martin T. Ferris, Fernando Pardo-Manuel de Villena, Mark T. Heise, Ralph S. Baric, View ORCID ProfileJennifer M. Lund

doi: https://doi.org/10.1101/2020.09.21.306837

Jessica B. Graham

1Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA

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Jessica L. Swarts

1Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA

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Sarah R. Leist

2Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC

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Alexandra Schäfer

2Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC

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Vineet D. Menachery

2Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC

3Department of Microbiology and Immunology, University of Texas Medical Center, Galveston, TX

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Lisa E. Gralinski

2Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC

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Sophia Jeng

4OHSU Knight Cancer Institute, Oregon Health & Science University, Portland, OR

5Oregon Clinical and Translational Research Institute, Oregon Health & Science University, Portland, OR

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Darla R. Miller

6Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC

7Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC

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Michael A. Mooney

5Oregon Clinical and Translational Research Institute, Oregon Health & Science University, Portland, OR

8Division of Bioinformatics and Computational Biology, Department of Medical Informatics and Clinical Epidemiology, Oregon Health & Science University, Portland, OR

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Shannon K. McWeeney

4OHSU Knight Cancer Institute, Oregon Health & Science University, Portland, OR

5Oregon Clinical and Translational Research Institute, Oregon Health & Science University, Portland, OR

8Division of Bioinformatics and Computational Biology, Department of Medical Informatics and Clinical Epidemiology, Oregon Health & Science University, Portland, OR

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Martin T. Ferris

6Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC

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Fernando Pardo-Manuel de Villena

6Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC

7Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC

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Mark T. Heise

6Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC

7Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC

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Ralph S. Baric

2Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC

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Jennifer M. Lund

1Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA

9Department of Global Health, University of Washington, Seattle, WA

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ORCID record for Jennifer M. Lund
For correspondence: jlund@fredhutch.org

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Baseline T cell immune phenotypes predict virologic and disease control upon SARS-CoV infection

bioRxiv 2020.09.21.306837; doi: https://doi.org/10.1101/2020.09.21.306837

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Baseline T cell immune phenotypes predict virologic and disease control upon SARS-CoV infection

bioRxiv 2020.09.21.306837; doi: https://doi.org/10.1101/2020.09.21.306837

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