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Broad-Spectrum, Patient-Adaptable Inhaled Niclosamide-Lysozyme Particles are Efficacious Against Coronaviruses in Lethal Murine Infection Models

View ORCID ProfileAshlee D. Brunaugh, Hyojong Seo, View ORCID ProfileZachary Warnken, Li Ding, Sang Heui Seo, View ORCID ProfileHugh D.C. Smyth
doi: https://doi.org/10.1101/2020.09.24.310490
Ashlee D. Brunaugh
1Division of Molecular Pharmaceutics and Drug Delivery, College of Pharmacy, University of Texas at Austin, 2409 University Ave, Austin TX, 78712
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  • ORCID record for Ashlee D. Brunaugh
Hyojong Seo
1Division of Molecular Pharmaceutics and Drug Delivery, College of Pharmacy, University of Texas at Austin, 2409 University Ave, Austin TX, 78712
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Zachary Warnken
1Division of Molecular Pharmaceutics and Drug Delivery, College of Pharmacy, University of Texas at Austin, 2409 University Ave, Austin TX, 78712
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Li Ding
1Division of Molecular Pharmaceutics and Drug Delivery, College of Pharmacy, University of Texas at Austin, 2409 University Ave, Austin TX, 78712
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Sang Heui Seo
2Laboratory of Influenza Research, College of Veterinary Medicine, Chungnam National University, 99 Dae-Hak Ro, Yoseong Gu, Dajeon, Korea, 34134
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Hugh D.C. Smyth
1Division of Molecular Pharmaceutics and Drug Delivery, College of Pharmacy, University of Texas at Austin, 2409 University Ave, Austin TX, 78712
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  • ORCID record for Hugh D.C. Smyth
  • For correspondence: hugh.smyth@austin.utexas.edu
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Article Information

doi 
https://doi.org/10.1101/2020.09.24.310490
History 
  • September 24, 2020.

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  • You are currently viewing Version 1 of this article (September 24, 2020 - 14:40).
  • View Version 2, the most recent version of this article.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Ashlee D. Brunaugh1,
  2. Hyojong Seo1,
  3. Zachary Warnken1,
  4. Li Ding1,
  5. Sang Heui Seo2 and
  6. Hugh D.C. Smyth1,*
  1. 1Division of Molecular Pharmaceutics and Drug Delivery, College of Pharmacy, University of Texas at Austin, 2409 University Ave, Austin TX, 78712
  2. 2Laboratory of Influenza Research, College of Veterinary Medicine, Chungnam National University, 99 Dae-Hak Ro, Yoseong Gu, Dajeon, Korea, 34134
  1. ↵*Corresponding author; email: hugh.smyth{at}austin.utexas.edu
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Posted September 24, 2020.
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Broad-Spectrum, Patient-Adaptable Inhaled Niclosamide-Lysozyme Particles are Efficacious Against Coronaviruses in Lethal Murine Infection Models
Ashlee D. Brunaugh, Hyojong Seo, Zachary Warnken, Li Ding, Sang Heui Seo, Hugh D.C. Smyth
bioRxiv 2020.09.24.310490; doi: https://doi.org/10.1101/2020.09.24.310490
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Broad-Spectrum, Patient-Adaptable Inhaled Niclosamide-Lysozyme Particles are Efficacious Against Coronaviruses in Lethal Murine Infection Models
Ashlee D. Brunaugh, Hyojong Seo, Zachary Warnken, Li Ding, Sang Heui Seo, Hugh D.C. Smyth
bioRxiv 2020.09.24.310490; doi: https://doi.org/10.1101/2020.09.24.310490

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