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Broad-Spectrum, Patient-Adaptable Inhaled Niclosamide-Lysozyme Particles are Efficacious Against Coronaviruses in Lethal Murine Infection Models

View ORCID ProfileAshlee D. Brunaugh, Hyojong Seo, View ORCID ProfileZachary Warnken, Li Ding, Sang Heui Seo, View ORCID ProfileHugh D.C. Smyth
doi: https://doi.org/10.1101/2020.09.24.310490
Ashlee D. Brunaugh
1Division of Molecular Pharmaceutics and Drug Delivery, College of Pharmacy, University of Texas at Austin, 2409 University Ave, Austin TX, 78712
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  • ORCID record for Ashlee D. Brunaugh
Hyojong Seo
1Division of Molecular Pharmaceutics and Drug Delivery, College of Pharmacy, University of Texas at Austin, 2409 University Ave, Austin TX, 78712
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Zachary Warnken
1Division of Molecular Pharmaceutics and Drug Delivery, College of Pharmacy, University of Texas at Austin, 2409 University Ave, Austin TX, 78712
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Li Ding
1Division of Molecular Pharmaceutics and Drug Delivery, College of Pharmacy, University of Texas at Austin, 2409 University Ave, Austin TX, 78712
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Sang Heui Seo
2Laboratory of Influenza Research, College of Veterinary Medicine, Chungnam National University, 99 Dae-Hak Ro, Yoseong Gu, Dajeon, Korea, 34134
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Hugh D.C. Smyth
1Division of Molecular Pharmaceutics and Drug Delivery, College of Pharmacy, University of Texas at Austin, 2409 University Ave, Austin TX, 78712
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  • ORCID record for Hugh D.C. Smyth
  • For correspondence: hugh.smyth@austin.utexas.edu
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  • Supplementary Figure 1[supplements/310490_file03.pdf]
  • Supplementary Table 1[supplements/310490_file04.pdf]
  • Supplementary Table 2[supplements/310490_file05.pdf]
  • Supplementary Table 3[supplements/310490_file06.pdf]
  • Supplementary Table 4[supplements/310490_file07.pdf]
  • Supplementary Table 5[supplements/310490_file08.pdf]
  • Supplementary Table 6[supplements/310490_file09.pdf]
  • Supplementary Table 7[supplements/310490_file10.pdf]
  • Supplementary Table 8[supplements/310490_file11.pdf]
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Posted September 24, 2020.
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Broad-Spectrum, Patient-Adaptable Inhaled Niclosamide-Lysozyme Particles are Efficacious Against Coronaviruses in Lethal Murine Infection Models
Ashlee D. Brunaugh, Hyojong Seo, Zachary Warnken, Li Ding, Sang Heui Seo, Hugh D.C. Smyth
bioRxiv 2020.09.24.310490; doi: https://doi.org/10.1101/2020.09.24.310490
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Broad-Spectrum, Patient-Adaptable Inhaled Niclosamide-Lysozyme Particles are Efficacious Against Coronaviruses in Lethal Murine Infection Models
Ashlee D. Brunaugh, Hyojong Seo, Zachary Warnken, Li Ding, Sang Heui Seo, Hugh D.C. Smyth
bioRxiv 2020.09.24.310490; doi: https://doi.org/10.1101/2020.09.24.310490

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