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The novel anti-CRISPR AcrIIA22 relieves DNA torsion in target plasmids and impairs SpyCas9 activity
View ORCID ProfileKevin J. Forsberg, View ORCID ProfileDanica T. Schmidtke, Rachel Werther, Ruben V. Uribe, View ORCID ProfileDeanna Hausman, Morten O.A. Sommer, Barry L. Stoddard, Brett K. Kaiser, View ORCID ProfileHarmit S. Malik
doi: https://doi.org/10.1101/2020.09.28.317578
Kevin J. Forsberg
aDivision of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109 USA
bHoward Hughes Medical Institute, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109 USA
Danica T. Schmidtke
aDivision of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109 USA
Rachel Werther
aDivision of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109 USA
Ruben V. Uribe
cNovo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Lyngby 2800, Denmark
Deanna Hausman
aDivision of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109 USA
Morten O.A. Sommer
cNovo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Lyngby 2800, Denmark
Barry L. Stoddard
aDivision of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109 USA
Brett K. Kaiser
aDivision of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109 USA
dDepartment of Biology, Seattle University, 901 12th Avenue, Seattle, WA 98122, USA
Harmit S. Malik
aDivision of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109 USA
bHoward Hughes Medical Institute, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109 USA
Article usage
Posted September 27, 2021.
The novel anti-CRISPR AcrIIA22 relieves DNA torsion in target plasmids and impairs SpyCas9 activity
Kevin J. Forsberg, Danica T. Schmidtke, Rachel Werther, Ruben V. Uribe, Deanna Hausman, Morten O.A. Sommer, Barry L. Stoddard, Brett K. Kaiser, Harmit S. Malik
bioRxiv 2020.09.28.317578; doi: https://doi.org/10.1101/2020.09.28.317578
The novel anti-CRISPR AcrIIA22 relieves DNA torsion in target plasmids and impairs SpyCas9 activity
Kevin J. Forsberg, Danica T. Schmidtke, Rachel Werther, Ruben V. Uribe, Deanna Hausman, Morten O.A. Sommer, Barry L. Stoddard, Brett K. Kaiser, Harmit S. Malik
bioRxiv 2020.09.28.317578; doi: https://doi.org/10.1101/2020.09.28.317578
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