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Ontogenetic Oxycodone Exposure Affects Early-Life Communicative Behaviors, Sensorimotor Reflexes, and Weight Trajectory in Mice

Elena Minakova, View ORCID ProfileSimona Sarafinovska, View ORCID ProfileMarwa O. Mikati, View ORCID ProfileKia Barclay, Katherine B. McCullough, View ORCID ProfileJoseph D. Dougherty, View ORCID ProfileReam Al-Hasani, View ORCID ProfileSusan E. Maloney
doi: https://doi.org/10.1101/2020.09.30.321372
Elena Minakova
1Department of Pediatrics, Washington University in St. Louis, MO, USA
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Simona Sarafinovska
2Department of Genetics, Washington University in St. Louis, MO, USA
3Department of Psychiatry, Washington University in St. Louis, MO, USA
4Medical Scientist Training Program, Washington University in St. Louis, MO, USA
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  • ORCID record for Simona Sarafinovska
Marwa O. Mikati
3Department of Psychiatry, Washington University in St. Louis, MO, USA
5Division of Biology and Biomedical Sciences, Washington University in St. Louis, MO, USA
6Department of Anesthesiology, Washington University in St. Louis, MO, USA
7Washington University Pain Center, Washington University in St. Louis, MO, USA
8Center for Clinical Pharmacology, St. Louis College of Pharmacy, MO, USA
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  • ORCID record for Marwa O. Mikati
Kia Barclay
5Division of Biology and Biomedical Sciences, Washington University in St. Louis, MO, USA
6Department of Anesthesiology, Washington University in St. Louis, MO, USA
7Washington University Pain Center, Washington University in St. Louis, MO, USA
8Center for Clinical Pharmacology, St. Louis College of Pharmacy, MO, USA
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  • ORCID record for Kia Barclay
Katherine B. McCullough
2Department of Genetics, Washington University in St. Louis, MO, USA
3Department of Psychiatry, Washington University in St. Louis, MO, USA
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Joseph D. Dougherty
2Department of Genetics, Washington University in St. Louis, MO, USA
3Department of Psychiatry, Washington University in St. Louis, MO, USA
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  • ORCID record for Joseph D. Dougherty
Ream Al-Hasani
5Division of Biology and Biomedical Sciences, Washington University in St. Louis, MO, USA
6Department of Anesthesiology, Washington University in St. Louis, MO, USA
7Washington University Pain Center, Washington University in St. Louis, MO, USA
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  • For correspondence: al-hasanir@wustl.edu maloneys@wustl.edu
Susan E. Maloney
3Department of Psychiatry, Washington University in St. Louis, MO, USA
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  • ORCID record for Susan E. Maloney
  • For correspondence: al-hasanir@wustl.edu maloneys@wustl.edu
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Article Information

doi 
https://doi.org/10.1101/2020.09.30.321372
History 
  • October 2, 2020.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.

Author Information

  1. Elena Minakova1,*,
  2. Simona Sarafinovska2,3,4,*,
  3. Marwa O. Mikati3,5,6,7,8,
  4. Kia Barclay5,6,7,8,
  5. Katherine B. McCullough2,3,
  6. Joseph D. Dougherty2,3,
  7. Ream Al-Hasani5,6,7,†,‡ and
  8. Susan E. Maloney3,†,‡
  1. 1Department of Pediatrics, Washington University in St. Louis, MO, USA
  2. 2Department of Genetics, Washington University in St. Louis, MO, USA
  3. 3Department of Psychiatry, Washington University in St. Louis, MO, USA
  4. 4Medical Scientist Training Program, Washington University in St. Louis, MO, USA
  5. 5Division of Biology and Biomedical Sciences, Washington University in St. Louis, MO, USA
  6. 6Department of Anesthesiology, Washington University in St. Louis, MO, USA
  7. 7Washington University Pain Center, Washington University in St. Louis, MO, USA
  8. 8Center for Clinical Pharmacology, St. Louis College of Pharmacy, MO, USA
  1. ↵‡Correspondence: Dr. Ream Al-Hasani, Center for Clinical Pharmacology, St. Louis College of Pharmacy, Washington University School of Medicine, Campus Box 8054, 660 South Euclid Avenue, St. Louis, MO 63110-1093, (314) 446-8158, al-hasanir{at}wustl.edu, Dr. Susan E. Maloney, Washington University School of Medicine, Department of Psychiatry, Campus Box 8232, 660 South Euclid Avenue, St. Louis, MO 63110-1093, (314) 362-3774, maloneys{at}wustl.edu
  1. ↵*† Authors contributed equally.

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Ontogenetic Oxycodone Exposure Affects Early-Life Communicative Behaviors, Sensorimotor Reflexes, and Weight Trajectory in Mice
Elena Minakova, Simona Sarafinovska, Marwa O. Mikati, Kia Barclay, Katherine B. McCullough, Joseph D. Dougherty, Ream Al-Hasani, Susan E. Maloney
bioRxiv 2020.09.30.321372; doi: https://doi.org/10.1101/2020.09.30.321372
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Ontogenetic Oxycodone Exposure Affects Early-Life Communicative Behaviors, Sensorimotor Reflexes, and Weight Trajectory in Mice
Elena Minakova, Simona Sarafinovska, Marwa O. Mikati, Kia Barclay, Katherine B. McCullough, Joseph D. Dougherty, Ream Al-Hasani, Susan E. Maloney
bioRxiv 2020.09.30.321372; doi: https://doi.org/10.1101/2020.09.30.321372

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