A polymer gel index-matched to water enables diverse applications in fluorescence microscopy

Xiaofei Han; Yijun Su; Hamilton White; Kate M. O’Neill; Nicole Y. Morgan; Ryan Christensen; Deepika Potarazu; Harshad D. Vishwasrao; Stephen Xu; Yilun Sun; Shar-yin Huang; Mark W. Moyle; Qionghai Dai; Yves Pommier; Edward Giniger; Dirk R. Albrecht; Roland Probst; Hari Shroff

doi:10.1101/2020.10.04.324996

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A polymer gel index-matched to water enables diverse applications in fluorescence microscopy

Xiaofei Han, Yijun Su, Hamilton White, Kate M. O’Neill, Nicole Y. Morgan, Ryan Christensen, Deepika Potarazu, Harshad D. Vishwasrao, Stephen Xu, Yilun Sun, Shar-yin Huang, Mark W. Moyle, Qionghai Dai, Yves Pommier, Edward Giniger, Dirk R. Albrecht, Roland Probst, Hari Shroff

doi: https://doi.org/10.1101/2020.10.04.324996

Xiaofei Han

1Laboratory of High Resolution Optical Imaging, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland, USA

2Department of Automation, Tsinghua University, 100084, Beijing, China

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For correspondence: hxftsinghua@126.com suy4nih@gmail.com hawhite@wpi.edu

Yijun Su

1Laboratory of High Resolution Optical Imaging, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland, USA

3Advanced Imaging and Microscopy Resource, National Institutes of Health, Bethesda, Maryland, USA

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For correspondence: hxftsinghua@126.com suy4nih@gmail.com hawhite@wpi.edu

Hamilton White

4Department of Biomedical Engineering, Worcester Polytechnic Institute, 100 Institute Road, Worcester, MA, 01609, USA

5Department of Neurobiology, University of Massachusetts Medical School, Worcester, MA 01655, USA

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For correspondence: hxftsinghua@126.com suy4nih@gmail.com hawhite@wpi.edu

Kate M. O’Neill

6National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD, 20892, USA

7Institute for Physical Science and Technology, University of Maryland College Park, College Park, Maryland, USA

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Nicole Y. Morgan

8National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland, USA

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Ryan Christensen

1Laboratory of High Resolution Optical Imaging, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland, USA

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Deepika Potarazu

1Laboratory of High Resolution Optical Imaging, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland, USA

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Harshad D. Vishwasrao

3Advanced Imaging and Microscopy Resource, National Institutes of Health, Bethesda, Maryland, USA

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Stephen Xu

1Laboratory of High Resolution Optical Imaging, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland, USA

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Yilun Sun

9Developmental Therapeutics Branch and Laboratory of Molecular Pharmacology, Center for Cancer Research, National Institutes of Health, Bethesda, Maryland, USA

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Shar-yin Huang

9Developmental Therapeutics Branch and Laboratory of Molecular Pharmacology, Center for Cancer Research, National Institutes of Health, Bethesda, Maryland, USA

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Mark W. Moyle

10Department of Neuroscience and Department of Cell Biology, Yale University School of Medicine, New Haven, CT 06536, USA

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Qionghai Dai

2Department of Automation, Tsinghua University, 100084, Beijing, China

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Yves Pommier

9Developmental Therapeutics Branch and Laboratory of Molecular Pharmacology, Center for Cancer Research, National Institutes of Health, Bethesda, Maryland, USA

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Edward Giniger

6National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD, 20892, USA

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Dirk R. Albrecht

4Department of Biomedical Engineering, Worcester Polytechnic Institute, 100 Institute Road, Worcester, MA, 01609, USA

11Department of Biology and Biotechnology, Worcester Polytechnic Institute, 100 Institute Road, Worcester, MA, 01609, USA

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Roland Probst

12ACUITYnano, Innovation in Biomedical Imaging, North Bethesda, Maryland, USA

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Hari Shroff

1Laboratory of High Resolution Optical Imaging, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland, USA

3Advanced Imaging and Microscopy Resource, National Institutes of Health, Bethesda, Maryland, USA

13Marine Biological Laboratory Fellows Program, Woods Hole, MA, USA

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