A polymer gel index-matched to water enables diverse applications in fluorescence microscopy

Xiaofei Han; Yijun Su; Hamilton White; Kate M. O’Neill; Nicole Y. Morgan; Ryan Christensen; Deepika Potarazu; Harshad D. Vishwasrao; Stephen Xu; Yilun Sun; Shar-yin Huang; Mark W. Moyle; Qionghai Dai; Yves Pommier; Edward Giniger; Dirk R. Albrecht; Roland Probst; Hari Shroff

doi:10.1101/2020.10.04.324996

New Results

A polymer gel index-matched to water enables diverse applications in fluorescence microscopy

Xiaofei Han, Yijun Su, Hamilton White, Kate M. O’Neill, Nicole Y. Morgan, Ryan Christensen, Deepika Potarazu, Harshad D. Vishwasrao, Stephen Xu, Yilun Sun, Shar-yin Huang, Mark W. Moyle, Qionghai Dai, Yves Pommier, Edward Giniger, Dirk R. Albrecht, Roland Probst, Hari Shroff

doi: https://doi.org/10.1101/2020.10.04.324996

Xiaofei Han

1Laboratory of High Resolution Optical Imaging, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland, USA

2Department of Automation, Tsinghua University, 100084, Beijing, China

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
For correspondence: hxftsinghua@126.com suy4nih@gmail.com hawhite@wpi.edu

Yijun Su

1Laboratory of High Resolution Optical Imaging, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland, USA

3Advanced Imaging and Microscopy Resource, National Institutes of Health, Bethesda, Maryland, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
For correspondence: hxftsinghua@126.com suy4nih@gmail.com hawhite@wpi.edu

Hamilton White

4Department of Biomedical Engineering, Worcester Polytechnic Institute, 100 Institute Road, Worcester, MA, 01609, USA

5Department of Neurobiology, University of Massachusetts Medical School, Worcester, MA 01655, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
For correspondence: hxftsinghua@126.com suy4nih@gmail.com hawhite@wpi.edu

Kate M. O’Neill

6National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD, 20892, USA

7Institute for Physical Science and Technology, University of Maryland College Park, College Park, Maryland, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Nicole Y. Morgan

8National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Ryan Christensen

1Laboratory of High Resolution Optical Imaging, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Deepika Potarazu

1Laboratory of High Resolution Optical Imaging, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Harshad D. Vishwasrao

3Advanced Imaging and Microscopy Resource, National Institutes of Health, Bethesda, Maryland, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Stephen Xu

1Laboratory of High Resolution Optical Imaging, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Yilun Sun

9Developmental Therapeutics Branch and Laboratory of Molecular Pharmacology, Center for Cancer Research, National Institutes of Health, Bethesda, Maryland, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Shar-yin Huang

9Developmental Therapeutics Branch and Laboratory of Molecular Pharmacology, Center for Cancer Research, National Institutes of Health, Bethesda, Maryland, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Mark W. Moyle

10Department of Neuroscience and Department of Cell Biology, Yale University School of Medicine, New Haven, CT 06536, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Qionghai Dai

2Department of Automation, Tsinghua University, 100084, Beijing, China

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Yves Pommier

9Developmental Therapeutics Branch and Laboratory of Molecular Pharmacology, Center for Cancer Research, National Institutes of Health, Bethesda, Maryland, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Edward Giniger

6National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD, 20892, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Dirk R. Albrecht

4Department of Biomedical Engineering, Worcester Polytechnic Institute, 100 Institute Road, Worcester, MA, 01609, USA

11Department of Biology and Biotechnology, Worcester Polytechnic Institute, 100 Institute Road, Worcester, MA, 01609, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Roland Probst

12ACUITYnano, Innovation in Biomedical Imaging, North Bethesda, Maryland, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Hari Shroff

1Laboratory of High Resolution Optical Imaging, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland, USA

3Advanced Imaging and Microscopy Resource, National Institutes of Health, Bethesda, Maryland, USA

13Marine Biological Laboratory Fellows Program, Woods Hole, MA, USA