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Metformin alleviates aging-associated cellular senescence of human adipose stem cells and derived adipocytes

Matthieu Mantecon, Laura Le Pelletier, Jennifer Gorwood, Martine Auclair, Michael Atlan, Bruno Fève, Jacqueline Capeau, Claire Lagathu, View ORCID ProfileVéronique Béréziat
doi: https://doi.org/10.1101/2020.10.05.326546
Matthieu Mantecon
1Sorbonne Université, Inserm UMR_S 938, Centre de Recherche Saint-Antoine (CRSA), RHU CARMMA, Institute of Cardiometabolism and Nutrition (ICAN), F-75012 Paris, France
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Laura Le Pelletier
1Sorbonne Université, Inserm UMR_S 938, Centre de Recherche Saint-Antoine (CRSA), RHU CARMMA, Institute of Cardiometabolism and Nutrition (ICAN), F-75012 Paris, France
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Jennifer Gorwood
1Sorbonne Université, Inserm UMR_S 938, Centre de Recherche Saint-Antoine (CRSA), RHU CARMMA, Institute of Cardiometabolism and Nutrition (ICAN), F-75012 Paris, France
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Martine Auclair
1Sorbonne Université, Inserm UMR_S 938, Centre de Recherche Saint-Antoine (CRSA), RHU CARMMA, Institute of Cardiometabolism and Nutrition (ICAN), F-75012 Paris, France
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Michael Atlan
1Sorbonne Université, Inserm UMR_S 938, Centre de Recherche Saint-Antoine (CRSA), RHU CARMMA, Institute of Cardiometabolism and Nutrition (ICAN), F-75012 Paris, France
2AP-HP, Tenon Hospital, Department of Plastic Surgery, F-75020 Paris, France
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Bruno Fève
1Sorbonne Université, Inserm UMR_S 938, Centre de Recherche Saint-Antoine (CRSA), RHU CARMMA, Institute of Cardiometabolism and Nutrition (ICAN), F-75012 Paris, France
3AP-HP, Saint-Antoine Hospital, Department of Endocrinology, PRISIS, F-75012 Paris, France
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Jacqueline Capeau
1Sorbonne Université, Inserm UMR_S 938, Centre de Recherche Saint-Antoine (CRSA), RHU CARMMA, Institute of Cardiometabolism and Nutrition (ICAN), F-75012 Paris, France
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Claire Lagathu
1Sorbonne Université, Inserm UMR_S 938, Centre de Recherche Saint-Antoine (CRSA), RHU CARMMA, Institute of Cardiometabolism and Nutrition (ICAN), F-75012 Paris, France
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Véronique Béréziat
1Sorbonne Université, Inserm UMR_S 938, Centre de Recherche Saint-Antoine (CRSA), RHU CARMMA, Institute of Cardiometabolism and Nutrition (ICAN), F-75012 Paris, France
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  • ORCID record for Véronique Béréziat
  • For correspondence: veronique.bereziat@inserm.fr
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Article Information

doi 
https://doi.org/10.1101/2020.10.05.326546
History 
  • October 6, 2020.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY 4.0 International license.

Author Information

  1. Matthieu Mantecon1,
  2. Laura Le Pelletier1,
  3. Jennifer Gorwood1,
  4. Martine Auclair1,
  5. Michael Atlan1,2,
  6. Bruno Fève1,3,
  7. Jacqueline Capeau1,
  8. Claire Lagathu1,* and
  9. Véronique Béréziat1,*,#
  1. 1Sorbonne Université, Inserm UMR_S 938, Centre de Recherche Saint-Antoine (CRSA), RHU CARMMA, Institute of Cardiometabolism and Nutrition (ICAN), F-75012 Paris, France
  2. 2AP-HP, Tenon Hospital, Department of Plastic Surgery, F-75020 Paris, France
  3. 3AP-HP, Saint-Antoine Hospital, Department of Endocrinology, PRISIS, F-75012 Paris, France
  1. ↵#Corresponding author: Véronique Béréziat veronique.bereziat{at}inserm.fr-+33140011321
  1. ↵* These two authors contributed equally to this work

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Posted October 06, 2020.
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Metformin alleviates aging-associated cellular senescence of human adipose stem cells and derived adipocytes
Matthieu Mantecon, Laura Le Pelletier, Jennifer Gorwood, Martine Auclair, Michael Atlan, Bruno Fève, Jacqueline Capeau, Claire Lagathu, Véronique Béréziat
bioRxiv 2020.10.05.326546; doi: https://doi.org/10.1101/2020.10.05.326546
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Metformin alleviates aging-associated cellular senescence of human adipose stem cells and derived adipocytes
Matthieu Mantecon, Laura Le Pelletier, Jennifer Gorwood, Martine Auclair, Michael Atlan, Bruno Fève, Jacqueline Capeau, Claire Lagathu, Véronique Béréziat
bioRxiv 2020.10.05.326546; doi: https://doi.org/10.1101/2020.10.05.326546

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