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Tractography dissection variability: what happens when 42 groups dissect 14 white matter bundles on the same dataset?

View ORCID ProfileKurt G. Schilling, View ORCID ProfileFrançois Rheault, View ORCID ProfileLaurent Petit, Colin B. Hansen, Vishwesh Nath, View ORCID ProfileFang-Cheng Yeh, Gabriel Girard, View ORCID ProfileMuhamed Barakovic, Jonathan Rafael-Patino, Thomas Yu, View ORCID ProfileElda Fischi-Gomez, Marco Pizzolato, Mario Ocampo-Pineda, View ORCID ProfileSimona Schiavi, View ORCID ProfileErick J. Canales-Rodríguez, View ORCID ProfileAlessandro Daducci, View ORCID ProfileCristina Granziera, Giorgio Innocenti, View ORCID ProfileJean-Philippe Thiran, View ORCID ProfileLaura Mancini, Stephen Wastling, View ORCID ProfileSirio Cocozza, View ORCID ProfileMaria Petracca, View ORCID ProfileGiuseppe Pontillo, Matteo Mancini, View ORCID ProfileSjoerd B. Vos, View ORCID ProfileVejay N. Vakharia, John S. Duncan, View ORCID ProfileHelena Melero, Lidia Manzanedo, Emilio Sanz-Morales, Ángel Peña-Melián, View ORCID ProfileFernando Calamante, Arnaud Attyé, View ORCID ProfileRyan P. Cabeen, Laura Korobova, Arthur W. Toga, View ORCID ProfileAnupa Ambili Vijayakumari, Drew Parker, Ragini Verma, Ahmed Radwan, Stefan Sunaert, Louise Emsell, Alberto De Luca, Alexander Leemans, View ORCID ProfileClaude J. Bajada, View ORCID ProfileHamied Haroon, View ORCID ProfileHojjatollah Azadbakht, View ORCID ProfileMaxime Chamberland, Sila Genc, View ORCID ProfileChantal M. W. Tax, Ping-Hong Yeh, Rujirutana Srikanchana, View ORCID ProfileColin D. Mcknight, View ORCID ProfileJoseph Yuan-Mou Yang, Jian Chen, Claire E. Kelly, View ORCID ProfileChun-Hung Yeh, Jerome Cochereau, Jerome J. Maller, Thomas Welton, Fabien Almairac, Kiran K Seunarine, Chris A. Clark, Fan Zhang, Nikos Makris, Alexandra Golby, Yogesh Rathi, View ORCID ProfileLauren J. O’Donnell, Yihao Xia, Dogu Baran Aydogan, Yonggang Shi, Francisco Guerreiro Fernandes, Mathijs Raemaekers, View ORCID ProfileShaun Warrington, Stijn Michielse, View ORCID ProfileAlonso Ramírez-Manzanares, View ORCID ProfileLuis Concha, View ORCID ProfileRamón Aranda, Mariano Rivera Meraz, View ORCID ProfileGarikoitz Lerma-Usabiaga, Lucas Roitman, View ORCID ProfileLucius S. Fekonja, Navona Calarco, Michael Joseph, Hajer Nakua, Aristotle N. Voineskos, Philippe Karan, Gabrielle Grenier, Jon Haitz Legarreta, View ORCID ProfileNagesh Adluru, Veena A. Nair, Vivek Prabhakaran, Andrew L. Alexander, View ORCID ProfileKoji Kamagata, Yuya Saito, Wataru Uchida, View ORCID ProfileChristina Andica, Masahiro Abe, Roza G. Bayrak, View ORCID ProfileClaudia A.M. Gandini Wheeler-Kingshott, View ORCID ProfileEgidio D’Angelo, View ORCID ProfileFulvia Palesi, View ORCID ProfileGiovanni Savini, Nicolò Rolandi, View ORCID ProfilePamela Guevara, Josselin Houenou, View ORCID ProfileNarciso López-López, Jean-François Mangin, Cyril Poupon, Claudio Román, Andrea Vázquez, Chiara Maffei, Mavilde Arantes, View ORCID ProfileJosé Paulo Andrade, Susana Maria Silva, Vince D. Calhoun, Eduardo Caverzasi, Simone Sacco, Michael Lauricella, View ORCID ProfileFranco Pestilli, View ORCID ProfileDaniel Bullock, Yang Zhan, Edith Brignoni-Perez, Catherine Lebel, Jess E Reynolds, View ORCID ProfileIgor Nestrasil, René Labounek, Christophe Lenglet, Amy Paulson, View ORCID ProfileStefania Aulicka, Sarah R. Heilbronner, View ORCID ProfileKatja Heuer, View ORCID ProfileBramsh Qamar Chandio, View ORCID ProfileJavier Guaje, View ORCID ProfileWei Tang, View ORCID ProfileEleftherios Garyfallidis, Rajikha Raja, Adam W. Anderson, View ORCID ProfileBennett A. Landman, View ORCID ProfileMaxime Descoteaux
doi: https://doi.org/10.1101/2020.10.07.321083
Kurt G. Schilling
aDepartment of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN
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  • ORCID record for Kurt G. Schilling
  • For correspondence: kurt.g.schilling.1@vumc.org
François Rheault
bSCIL, Université de Sherbrooke
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  • ORCID record for François Rheault
Laurent Petit
cGroupe dImagerie Neurofonctionnelle, Institut Des Maladies Neurodegeneratives, CNRS, CEA University of Bordeaux, Bordeaux, France
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  • ORCID record for Laurent Petit
Colin B. Hansen
dDepartment of Electrical Engineering and Computer Science, Vanderbilt University, Nashville, TN
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Vishwesh Nath
dDepartment of Electrical Engineering and Computer Science, Vanderbilt University, Nashville, TN
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Fang-Cheng Yeh
eDepartment of Neurological Surgery, University of Pittsburgh
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  • ORCID record for Fang-Cheng Yeh
Gabriel Girard
fCIBM Center for BioMedical Imaging, Lausanne, Switzerland
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Muhamed Barakovic
gTranslational Imaging in Neurology (ThINK), Department of Medicine and Biomedical Engineering, University Hospital and University of Basel, Basel, Switzerland
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  • ORCID record for Muhamed Barakovic
Jonathan Rafael-Patino
hSignal Processing Lab (LTS5), École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
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Thomas Yu
hSignal Processing Lab (LTS5), École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
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Elda Fischi-Gomez
hSignal Processing Lab (LTS5), École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
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  • ORCID record for Elda Fischi-Gomez
Marco Pizzolato
iDepartment of Applied Mathematics and Computer Science, Technical University of Denmark, Kongens Lyngby, Denmark
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Mario Ocampo-Pineda
jDepartment of Computer Science, University of Verona
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Simona Schiavi
jDepartment of Computer Science, University of Verona
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  • ORCID record for Simona Schiavi
Erick J. Canales-Rodríguez
hSignal Processing Lab (LTS5), École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
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  • ORCID record for Erick J. Canales-Rodríguez
Alessandro Daducci
jDepartment of Computer Science, University of Verona
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  • ORCID record for Alessandro Daducci
Cristina Granziera
gTranslational Imaging in Neurology (ThINK), Department of Medicine and Biomedical Engineering, University Hospital and University of Basel, Basel, Switzerland
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  • ORCID record for Cristina Granziera
Giorgio Innocenti
kDepartment of Neuroscience, Karolinska Institutet, Stockholm, Sweden
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Jean-Philippe Thiran
hSignal Processing Lab (LTS5), École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
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  • ORCID record for Jean-Philippe Thiran
Laura Mancini
lLysholm Department of Neuroradiology, National Hospital for Neurology & Neurosurgery, UCL Hospitals NHS Foundation Trust, London, United Kingdom
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Stephen Wastling
lLysholm Department of Neuroradiology, National Hospital for Neurology & Neurosurgery, UCL Hospitals NHS Foundation Trust, London, United Kingdom
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Sirio Cocozza
mDepartment of Advanced Biomedical Sciences, University “Federico II”, Naples, Italy
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Maria Petracca
nDepartment of Neurosciences and Reproductive and Odontostomatological Sciences, University “Federico II”, Naples, Italy
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  • ORCID record for Maria Petracca
Giuseppe Pontillo
mDepartment of Advanced Biomedical Sciences, University “Federico II”, Naples, Italy
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Matteo Mancini
oDepartment of Neuroscience, Brighton and Sussex Medical School, University of Sussex, Brighton, United Kingdom
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Sjoerd B. Vos
pCentre for Medical Image Computing, University College London, London, United Kingdom
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Vejay N. Vakharia
qDepartment of Clinical and Experimental Epilepsy, University College London, London, United Kingdom
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John S. Duncan
rEpilepsy Society MRI Unit, Chalfont St Peter, United Kingdom
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Helena Melero
sLaboratorio de Análisis de Imagen Médica y Biometría (LAIMBIO), Universidad Rey Juan Carlos, Madrid, Spain
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  • ORCID record for Helena Melero
Lidia Manzanedo
tFacultad de Ciencias de la Salud, Universidad Rey Juan Carlos, Madrid, Spain
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Emilio Sanz-Morales
sLaboratorio de Análisis de Imagen Médica y Biometría (LAIMBIO), Universidad Rey Juan Carlos, Madrid, Spain
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Ángel Peña-Melián
uDepartamento de Anatomía, Facultad de Medicina, Universidad Complutense de Madrid, Madrid, Spain
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Fernando Calamante
vSydney Imaging and School of Biomedical Engineering, The University of Sydney, Sydney, Australia
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Arnaud Attyé
wSchool of Biomedical Engineering, The University of Sydney, Sydney, Australia
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Ryan P. Cabeen
xLaboratory of Neuro Imaging, Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA
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Laura Korobova
yCenter for Integrative Connectomics, Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA
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Arthur W. Toga
xLaboratory of Neuro Imaging, Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA
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Anupa Ambili Vijayakumari
zDepartment of Radiology, University of Pennsylvania, Philadelphia, PA
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Drew Parker
zDepartment of Radiology, University of Pennsylvania, Philadelphia, PA
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Ragini Verma
zDepartment of Radiology, University of Pennsylvania, Philadelphia, PA
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Ahmed Radwan
aaKU Leuven, Department of Imaging and Pathology, Translational MRI, B-3000, Leuven, Belgium
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Stefan Sunaert
aaKU Leuven, Department of Imaging and Pathology, Translational MRI, B-3000, Leuven, Belgium
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Louise Emsell
aaKU Leuven, Department of Imaging and Pathology, Translational MRI, B-3000, Leuven, Belgium
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Alberto De Luca
bbPROVIDI Lab, UMC Utrecht, The Netherlands
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Alexander Leemans
bbPROVIDI Lab, UMC Utrecht, The Netherlands
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Claude J. Bajada
ccDepartment of Physiology and Biochemistry, Faculty of Medicine and Surgery, University of Malta, Malta
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Hamied Haroon
ddDivision of Neuroscience & Experimental Psychology, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom
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Hojjatollah Azadbakht
eeAINOSTICS Limited, London, United Kingdom
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Maxime Chamberland
ffCardiff University Brain Research Imaging Centre (CUBRIC), Cardiff University, Cardiff, United Kingdom
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Sila Genc
ffCardiff University Brain Research Imaging Centre (CUBRIC), Cardiff University, Cardiff, United Kingdom
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Chantal M. W. Tax
ffCardiff University Brain Research Imaging Centre (CUBRIC), Cardiff University, Cardiff, United Kingdom
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Ping-Hong Yeh
ggNational Intrepid Center of Excellence, Walter Reed National Military Medical Center, Bethesda, MD, USA
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Rujirutana Srikanchana
ggNational Intrepid Center of Excellence, Walter Reed National Military Medical Center, Bethesda, MD, USA
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Colin D. Mcknight
aDepartment of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN
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Joseph Yuan-Mou Yang
hhDepartment of Neurosurgery, Neuroscience Advanced Clinical Imaging Suite (NACIS), Royal Children’s Hospital, Parkville, Melbourne, Australia
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Jian Chen
iiDevelopmental Imaging, Murdoch Children’s Research Institute, Melbourne, Australia
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Claire E. Kelly
ijVictorian Infant Brain Studies, Murdoch Children’s Research Institute, Melbourne, Australia
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Chun-Hung Yeh
jjInstitute for Radiological Research, Chang Gung University & Chang Gung Memorial Hospital, Taoyuan, Taiwan
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Jerome Cochereau
kkPoitiers University Hospital, France
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Jerome J. Maller
llMRI Clinical Science Specialist, General Electric Healthcare, Australia
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Thomas Welton
mmNational Neuroscience Institute, Singapore
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Fabien Almairac
nnNeurosurgery department, Hôpital Pasteur, University Hospital of Nice, Côte d’Azur University, France
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Kiran K Seunarine
ooDevelopmental Imaging and Biophysics Section, UCL GOS Institute of Child Health, London
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Chris A. Clark
ooDevelopmental Imaging and Biophysics Section, UCL GOS Institute of Child Health, London
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Fan Zhang
ppBrigham & Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA
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Nikos Makris
ppBrigham & Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA
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Alexandra Golby
ppBrigham & Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA
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Yogesh Rathi
ppBrigham & Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA
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Lauren J. O’Donnell
ppBrigham & Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA
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Yihao Xia
qqUniversity of Southern California, Keck School of Medicine, Neuroimaging and Informatics Institute, Los Angeles, California, United States
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Dogu Baran Aydogan
rrDepartment of Neuroscience and Biomedical Engineering, Aalto University School of Science, Espoo, Finland
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Yonggang Shi
qqUniversity of Southern California, Keck School of Medicine, Neuroimaging and Informatics Institute, Los Angeles, California, United States
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Francisco Guerreiro Fernandes
ssUMC Utrecht Brain Center, Department of Neurology&Neurosurgery, Utrecht, the Netherlands
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Mathijs Raemaekers
ssUMC Utrecht Brain Center, Department of Neurology&Neurosurgery, Utrecht, the Netherlands
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Shaun Warrington
ttSir Peter Mansfield Imaging Centre, School of Medicine, University of Nottingham, UK
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Stijn Michielse
uuDepartment of Neurosurgery, School for Mental Health and Neuroscience, Maastricht University
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Alonso Ramírez-Manzanares
vvCentro de Investigación en Matemáticas A.C. (CIMAT)
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Luis Concha
wwUniversidad Nacional Autonoma de Mexico, Institute of Neurobiology
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Ramón Aranda
xxCentro de Investigación Científica y de Educación Superior de Ensenada (CICESE-UT3), Cátedras-CONACyT
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Mariano Rivera Meraz
vvCentro de Investigación en Matemáticas A.C. (CIMAT)
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Garikoitz Lerma-Usabiaga
yyDepartment of Psychology, Stanford University, Stanford, California, USA
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Lucas Roitman
yyDepartment of Psychology, Stanford University, Stanford, California, USA
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Lucius S. Fekonja
zzDepartment of Neurosurgery, Charité - Universitätsmedizin Berlin, Berlin, Germany
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Navona Calarco
aaaKimel Family Translational Imaging-Genetics Laboratory, Research Imaging Centre, Centre for Addiction and Mental Health, Toronto, Ontario
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Michael Joseph
aaaKimel Family Translational Imaging-Genetics Laboratory, Research Imaging Centre, Centre for Addiction and Mental Health, Toronto, Ontario
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Hajer Nakua
aaaKimel Family Translational Imaging-Genetics Laboratory, Research Imaging Centre, Centre for Addiction and Mental Health, Toronto, Ontario
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Aristotle N. Voineskos
aaaKimel Family Translational Imaging-Genetics Laboratory, Research Imaging Centre, Centre for Addiction and Mental Health, Toronto, Ontario
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Philippe Karan
bSCIL, Université de Sherbrooke
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Gabrielle Grenier
bSCIL, Université de Sherbrooke
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Jon Haitz Legarreta
bSCIL, Université de Sherbrooke
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Nagesh Adluru
bbbUniversity of Wisconsin-Madison
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Veena A. Nair
bbbUniversity of Wisconsin-Madison
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Vivek Prabhakaran
bbbUniversity of Wisconsin-Madison
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Andrew L. Alexander
bbbUniversity of Wisconsin-Madison
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Koji Kamagata
cccDepartment of Radiology, Juntendo University Graduate School of Medicine, Tokyo Japan
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Yuya Saito
cccDepartment of Radiology, Juntendo University Graduate School of Medicine, Tokyo Japan
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Wataru Uchida
cccDepartment of Radiology, Juntendo University Graduate School of Medicine, Tokyo Japan
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Christina Andica
cccDepartment of Radiology, Juntendo University Graduate School of Medicine, Tokyo Japan
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Masahiro Abe
cccDepartment of Radiology, Juntendo University Graduate School of Medicine, Tokyo Japan
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Roza G. Bayrak
dDepartment of Electrical Engineering and Computer Science, Vanderbilt University, Nashville, TN
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Claudia A.M. Gandini Wheeler-Kingshott
dddNMR Research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, United Kingdom
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Egidio D’Angelo
eeeDepartment of Brain and Behavioral Sciences, University of Pavia, Italy
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Fulvia Palesi
eeeDepartment of Brain and Behavioral Sciences, University of Pavia, Italy
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Giovanni Savini
fffBrain MRI 3T Research Center, IRCCS Mondino Foundation, Pavia, Italy
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Abstract

White matter bundle segmentation using diffusion MRI fiber tractography has become the method of choice to identify white matter fiber pathways in vivo in human brains. However, like other analyses of complex data, there is considerable variability in segmentation protocols and techniques. This can result in different reconstructions of the same intended white matter pathways, which directly affects tractography results, quantification, and interpretation. In this study, we aim to evaluate and quantify the variability that arises from different protocols for bundle segmentation. Through an open call to users of fiber tractography, including anatomists, clinicians, and algorithm developers, 42 independent teams were given processed sets of human whole-brain streamlines and asked to segment 14 white matter fascicles on six subjects. In total, we received 57 different bundle segmentation protocols, which enabled detailed volume-based and streamline-based analyses of agreement and disagreement among protocols for each fiber pathway. Results show that even when given the exact same sets of underlying streamlines, the variability across protocols for bundle segmentation is greater than all other sources of variability in the virtual dissection process, including variability within protocols and variability across subjects. In order to foster the use of tractography bundle dissection in routine clinical settings, and as a fundamental analytical tool, future endeavors must aim to resolve and reduce this heterogeneity. Although external validation is needed to verify the anatomical accuracy of bundle dissections, reducing heterogeneity is a step towards reproducible research and may be achieved through the use of standard nomenclature and definitions of white matter bundles and well-chosen constraints and decisions in the dissection process.

Competing Interest Statement

The authors have declared no competing interest.

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Tractography dissection variability: what happens when 42 groups dissect 14 white matter bundles on the same dataset?
Kurt G. Schilling, François Rheault, Laurent Petit, Colin B. Hansen, Vishwesh Nath, Fang-Cheng Yeh, Gabriel Girard, Muhamed Barakovic, Jonathan Rafael-Patino, Thomas Yu, Elda Fischi-Gomez, Marco Pizzolato, Mario Ocampo-Pineda, Simona Schiavi, Erick J. Canales-Rodríguez, Alessandro Daducci, Cristina Granziera, Giorgio Innocenti, Jean-Philippe Thiran, Laura Mancini, Stephen Wastling, Sirio Cocozza, Maria Petracca, Giuseppe Pontillo, Matteo Mancini, Sjoerd B. Vos, Vejay N. Vakharia, John S. Duncan, Helena Melero, Lidia Manzanedo, Emilio Sanz-Morales, Ángel Peña-Melián, Fernando Calamante, Arnaud Attyé, Ryan P. Cabeen, Laura Korobova, Arthur W. Toga, Anupa Ambili Vijayakumari, Drew Parker, Ragini Verma, Ahmed Radwan, Stefan Sunaert, Louise Emsell, Alberto De Luca, Alexander Leemans, Claude J. Bajada, Hamied Haroon, Hojjatollah Azadbakht, Maxime Chamberland, Sila Genc, Chantal M. W. Tax, Ping-Hong Yeh, Rujirutana Srikanchana, Colin D. Mcknight, Joseph Yuan-Mou Yang, Jian Chen, Claire E. Kelly, Chun-Hung Yeh, Jerome Cochereau, Jerome J. Maller, Thomas Welton, Fabien Almairac, Kiran K Seunarine, Chris A. Clark, Fan Zhang, Nikos Makris, Alexandra Golby, Yogesh Rathi, Lauren J. O’Donnell, Yihao Xia, Dogu Baran Aydogan, Yonggang Shi, Francisco Guerreiro Fernandes, Mathijs Raemaekers, Shaun Warrington, Stijn Michielse, Alonso Ramírez-Manzanares, Luis Concha, Ramón Aranda, Mariano Rivera Meraz, Garikoitz Lerma-Usabiaga, Lucas Roitman, Lucius S. Fekonja, Navona Calarco, Michael Joseph, Hajer Nakua, Aristotle N. Voineskos, Philippe Karan, Gabrielle Grenier, Jon Haitz Legarreta, Nagesh Adluru, Veena A. Nair, Vivek Prabhakaran, Andrew L. Alexander, Koji Kamagata, Yuya Saito, Wataru Uchida, Christina Andica, Masahiro Abe, Roza G. Bayrak, Claudia A.M. Gandini Wheeler-Kingshott, Egidio D’Angelo, Fulvia Palesi, Giovanni Savini, Nicolò Rolandi, Pamela Guevara, Josselin Houenou, Narciso López-López, Jean-François Mangin, Cyril Poupon, Claudio Román, Andrea Vázquez, Chiara Maffei, Mavilde Arantes, José Paulo Andrade, Susana Maria Silva, Vince D. Calhoun, Eduardo Caverzasi, Simone Sacco, Michael Lauricella, Franco Pestilli, Daniel Bullock, Yang Zhan, Edith Brignoni-Perez, Catherine Lebel, Jess E Reynolds, Igor Nestrasil, René Labounek, Christophe Lenglet, Amy Paulson, Stefania Aulicka, Sarah R. Heilbronner, Katja Heuer, Bramsh Qamar Chandio, Javier Guaje, Wei Tang, Eleftherios Garyfallidis, Rajikha Raja, Adam W. Anderson, Bennett A. Landman, Maxime Descoteaux
bioRxiv 2020.10.07.321083; doi: https://doi.org/10.1101/2020.10.07.321083
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Tractography dissection variability: what happens when 42 groups dissect 14 white matter bundles on the same dataset?
Kurt G. Schilling, François Rheault, Laurent Petit, Colin B. Hansen, Vishwesh Nath, Fang-Cheng Yeh, Gabriel Girard, Muhamed Barakovic, Jonathan Rafael-Patino, Thomas Yu, Elda Fischi-Gomez, Marco Pizzolato, Mario Ocampo-Pineda, Simona Schiavi, Erick J. Canales-Rodríguez, Alessandro Daducci, Cristina Granziera, Giorgio Innocenti, Jean-Philippe Thiran, Laura Mancini, Stephen Wastling, Sirio Cocozza, Maria Petracca, Giuseppe Pontillo, Matteo Mancini, Sjoerd B. Vos, Vejay N. Vakharia, John S. Duncan, Helena Melero, Lidia Manzanedo, Emilio Sanz-Morales, Ángel Peña-Melián, Fernando Calamante, Arnaud Attyé, Ryan P. Cabeen, Laura Korobova, Arthur W. Toga, Anupa Ambili Vijayakumari, Drew Parker, Ragini Verma, Ahmed Radwan, Stefan Sunaert, Louise Emsell, Alberto De Luca, Alexander Leemans, Claude J. Bajada, Hamied Haroon, Hojjatollah Azadbakht, Maxime Chamberland, Sila Genc, Chantal M. W. Tax, Ping-Hong Yeh, Rujirutana Srikanchana, Colin D. Mcknight, Joseph Yuan-Mou Yang, Jian Chen, Claire E. Kelly, Chun-Hung Yeh, Jerome Cochereau, Jerome J. Maller, Thomas Welton, Fabien Almairac, Kiran K Seunarine, Chris A. Clark, Fan Zhang, Nikos Makris, Alexandra Golby, Yogesh Rathi, Lauren J. O’Donnell, Yihao Xia, Dogu Baran Aydogan, Yonggang Shi, Francisco Guerreiro Fernandes, Mathijs Raemaekers, Shaun Warrington, Stijn Michielse, Alonso Ramírez-Manzanares, Luis Concha, Ramón Aranda, Mariano Rivera Meraz, Garikoitz Lerma-Usabiaga, Lucas Roitman, Lucius S. Fekonja, Navona Calarco, Michael Joseph, Hajer Nakua, Aristotle N. Voineskos, Philippe Karan, Gabrielle Grenier, Jon Haitz Legarreta, Nagesh Adluru, Veena A. Nair, Vivek Prabhakaran, Andrew L. Alexander, Koji Kamagata, Yuya Saito, Wataru Uchida, Christina Andica, Masahiro Abe, Roza G. Bayrak, Claudia A.M. Gandini Wheeler-Kingshott, Egidio D’Angelo, Fulvia Palesi, Giovanni Savini, Nicolò Rolandi, Pamela Guevara, Josselin Houenou, Narciso López-López, Jean-François Mangin, Cyril Poupon, Claudio Román, Andrea Vázquez, Chiara Maffei, Mavilde Arantes, José Paulo Andrade, Susana Maria Silva, Vince D. Calhoun, Eduardo Caverzasi, Simone Sacco, Michael Lauricella, Franco Pestilli, Daniel Bullock, Yang Zhan, Edith Brignoni-Perez, Catherine Lebel, Jess E Reynolds, Igor Nestrasil, René Labounek, Christophe Lenglet, Amy Paulson, Stefania Aulicka, Sarah R. Heilbronner, Katja Heuer, Bramsh Qamar Chandio, Javier Guaje, Wei Tang, Eleftherios Garyfallidis, Rajikha Raja, Adam W. Anderson, Bennett A. Landman, Maxime Descoteaux
bioRxiv 2020.10.07.321083; doi: https://doi.org/10.1101/2020.10.07.321083

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