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Umbilical cord blood derived microglia-like cells to model COVID-19 exposure

Steven D. Sheridan, Jessica M. Thanos, Rose M. De Guzman, Liam T. McCrea, Joy Horng, Ting Fu, Carl M. Sellgren, Roy H. Perlis, Andrea G. Edlow
doi: https://doi.org/10.1101/2020.10.07.329748
Steven D. Sheridan
1Department of Psychiatry, Harvard Medical School, Boston, MA, USA
2Center for Genomic Medicine and Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA
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Jessica M. Thanos
1Department of Psychiatry, Harvard Medical School, Boston, MA, USA
2Center for Genomic Medicine and Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA
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Rose M. De Guzman
3Obstetrics, Gynecology, and Reproductive Biology, Harvard Medical School, Boston, MA, USA
4Vincent Center for Reproductive Biology, Massachusetts General Hospital, Boston, MA, USA
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Liam T. McCrea
1Department of Psychiatry, Harvard Medical School, Boston, MA, USA
2Center for Genomic Medicine and Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA
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Joy Horng
1Department of Psychiatry, Harvard Medical School, Boston, MA, USA
2Center for Genomic Medicine and Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA
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Ting Fu
1Department of Psychiatry, Harvard Medical School, Boston, MA, USA
2Center for Genomic Medicine and Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA
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Carl M. Sellgren
5Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden
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Roy H. Perlis
1Department of Psychiatry, Harvard Medical School, Boston, MA, USA
2Center for Genomic Medicine and Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA
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  • For correspondence: aedlow@mgh.harvard.edu rperlis@mgh.harvard.edu
Andrea G. Edlow
3Obstetrics, Gynecology, and Reproductive Biology, Harvard Medical School, Boston, MA, USA
4Vincent Center for Reproductive Biology, Massachusetts General Hospital, Boston, MA, USA
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  • For correspondence: aedlow@mgh.harvard.edu rperlis@mgh.harvard.edu
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Article Information

doi 
https://doi.org/10.1101/2020.10.07.329748
History 
  • October 7, 2020.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Steven D. Sheridan, PhD1,2,†,
  2. Jessica M. Thanos, BS1,2,†,
  3. Rose M. De Guzman, PhD3,4,
  4. Liam T. McCrea, BS1,2,
  5. Joy Horng, BS1,2,
  6. Ting Fu, BS1,2,
  7. Carl M. Sellgren, MD, PhD5,
  8. Roy H. Perlis, MD, MSc1,2,* and
  9. Andrea G. Edlow, MD, MSc3,4,*
  1. 1Department of Psychiatry, Harvard Medical School, Boston, MA, USA
  2. 2Center for Genomic Medicine and Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA
  3. 3Obstetrics, Gynecology, and Reproductive Biology, Harvard Medical School, Boston, MA, USA
  4. 4Vincent Center for Reproductive Biology, Massachusetts General Hospital, Boston, MA, USA
  5. 5Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden
  1. ↵*To whom correspondence should be addressed: Dr. Andrea G. Edlow, Vincent Center for Reproductive Biology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, Telephone: 617-724-6047; Fax: 617-726-0561, Email: aedlow{at}mgh.harvard.edu, Dr. Roy H. Perlis, Center for Genomic Medicine and Department of Psychiatry, Massachusetts General Hospital, 185 Cambridge Street, Boston, MA 02114, Telephone: 617-726-7426; Fax: 617-643-3080, Email: rperlis{at}mgh.harvard.edu
  1. ↵† These authors contributed equally to this work.

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Umbilical cord blood derived microglia-like cells to model COVID-19 exposure
Steven D. Sheridan, Jessica M. Thanos, Rose M. De Guzman, Liam T. McCrea, Joy Horng, Ting Fu, Carl M. Sellgren, Roy H. Perlis, Andrea G. Edlow
bioRxiv 2020.10.07.329748; doi: https://doi.org/10.1101/2020.10.07.329748
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Umbilical cord blood derived microglia-like cells to model COVID-19 exposure
Steven D. Sheridan, Jessica M. Thanos, Rose M. De Guzman, Liam T. McCrea, Joy Horng, Ting Fu, Carl M. Sellgren, Roy H. Perlis, Andrea G. Edlow
bioRxiv 2020.10.07.329748; doi: https://doi.org/10.1101/2020.10.07.329748

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