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Single-nucleus transcriptome analysis reveals cell type-specific molecular signatures across reward circuitry in the human brain
View ORCID ProfileMatthew N. Tran, View ORCID ProfileKristen R. Maynard, View ORCID ProfileAbby Spangler, View ORCID ProfileLeonardo Collado-Torres, View ORCID ProfileVijay Sadashivaiah, View ORCID ProfileMadhavi Tippani, View ORCID ProfileBrianna K. Barry, Dana B. Hancock, View ORCID ProfileStephanie C. Hicks, Joel E. Kleinman, Thomas M. Hyde, View ORCID ProfileKeri Martinowich, View ORCID ProfileAndrew E. Jaffe
doi: https://doi.org/10.1101/2020.10.07.329839
Matthew N. Tran
1Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD, 21205, USA
2McKusick-Nathans Institute, Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA
Kristen R. Maynard
1Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD, 21205, USA
Abby Spangler
1Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD, 21205, USA
Leonardo Collado-Torres
1Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD, 21205, USA
Vijay Sadashivaiah
1Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD, 21205, USA
Madhavi Tippani
1Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD, 21205, USA
Brianna K. Barry
1Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD, 21205, USA
3Department of Neuroscience, Johns Hopkins School of Medicine, Baltimore, MD, 21205, USA
Dana B. Hancock
4GenOmics, Bioinformatics, and Translational Research Center, Biostatistics and Epidemiology Division, RTI International, Research Triangle Park, NC, USA
Stephanie C. Hicks
5Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21205, USA
Joel E. Kleinman
1Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD, 21205, USA
6Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, MD, 21205, USA
Thomas M. Hyde
1Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD, 21205, USA
6Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, MD, 21205, USA
7Department of Neurology, Johns Hopkins School of Medicine, Baltimore, MD, 21205, USA
Keri Martinowich
1Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD, 21205, USA
3Department of Neuroscience, Johns Hopkins School of Medicine, Baltimore, MD, 21205, USA
6Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, MD, 21205, USA
Andrew E. Jaffe
1Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD, 21205, USA
2McKusick-Nathans Institute, Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA
3Department of Neuroscience, Johns Hopkins School of Medicine, Baltimore, MD, 21205, USA
5Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21205, USA
6Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, MD, 21205, USA
8Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21205, USA
Posted October 08, 2020.
Single-nucleus transcriptome analysis reveals cell type-specific molecular signatures across reward circuitry in the human brain
Matthew N. Tran, Kristen R. Maynard, Abby Spangler, Leonardo Collado-Torres, Vijay Sadashivaiah, Madhavi Tippani, Brianna K. Barry, Dana B. Hancock, Stephanie C. Hicks, Joel E. Kleinman, Thomas M. Hyde, Keri Martinowich, Andrew E. Jaffe
bioRxiv 2020.10.07.329839; doi: https://doi.org/10.1101/2020.10.07.329839
Single-nucleus transcriptome analysis reveals cell type-specific molecular signatures across reward circuitry in the human brain
Matthew N. Tran, Kristen R. Maynard, Abby Spangler, Leonardo Collado-Torres, Vijay Sadashivaiah, Madhavi Tippani, Brianna K. Barry, Dana B. Hancock, Stephanie C. Hicks, Joel E. Kleinman, Thomas M. Hyde, Keri Martinowich, Andrew E. Jaffe
bioRxiv 2020.10.07.329839; doi: https://doi.org/10.1101/2020.10.07.329839
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