Brain-Restricted mTOR Inhibition with Binary Pharmacology

Ziyang Zhang; Qiwen Fan; Xujun Luo; Kevin J. Lou; William A. Weiss; Kevan M. Shokat

doi:10.1101/2020.10.12.336677

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Brain-Restricted mTOR Inhibition with Binary Pharmacology

View ORCID ProfileZiyang Zhang, Qiwen Fan, Xujun Luo, Kevin J. Lou, William A. Weiss, View ORCID ProfileKevan M. Shokat

doi: https://doi.org/10.1101/2020.10.12.336677

Ziyang Zhang

1Department of Cellular and Molecular Pharmacology and Howard Hughes Medical Institute, University of California, San Francisco, California

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Qiwen Fan

2Helen Diller Family Comprehensive Cancer Center, San Francisco, California

3Department of Neurology, University of California, San Francisco, California

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Xujun Luo

2Helen Diller Family Comprehensive Cancer Center, San Francisco, California

3Department of Neurology, University of California, San Francisco, California

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Kevin J. Lou

1Department of Cellular and Molecular Pharmacology and Howard Hughes Medical Institute, University of California, San Francisco, California

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William A. Weiss

2Helen Diller Family Comprehensive Cancer Center, San Francisco, California

3Department of Neurology, University of California, San Francisco, California

4Department of Pediatrics, University of California, San Francisco, California

5Department of Neurological Surgery, University of California, San Francisco, California

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Kevan M. Shokat

1Department of Cellular and Molecular Pharmacology and Howard Hughes Medical Institute, University of California, San Francisco, California

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For correspondence: kevan.shokat@ucsf.edu

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Brain-Restricted mTOR Inhibition with Binary Pharmacology

Ziyang Zhang, Qiwen Fan, Xujun Luo, Kevin J. Lou, William A. Weiss, Kevan M. Shokat

bioRxiv 2020.10.12.336677; doi: https://doi.org/10.1101/2020.10.12.336677

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Brain-Restricted mTOR Inhibition with Binary Pharmacology

Ziyang Zhang, Qiwen Fan, Xujun Luo, Kevin J. Lou, William A. Weiss, Kevan M. Shokat

bioRxiv 2020.10.12.336677; doi: https://doi.org/10.1101/2020.10.12.336677

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