Skip to main content
bioRxiv
  • Home
  • About
  • Submit
  • ALERTS / RSS
Advanced Search
New Results

Tau pathology spreads between anatomically-connected regions of the brain and is modulated by a LRRK2 mutation

View ORCID ProfileMichael X. Henderson, Eli J. Cornblath, Howard L. Li, Lakshmi Changolkar, Bin Zhang, Hannah J. Brown, Ronald J. Gathagan, Modupe F. Olufemi, View ORCID ProfileDanielle S. Bassett, John Q. Trojanowski, Virginia M.Y. Lee
doi: https://doi.org/10.1101/2020.10.13.337857
Michael X. Henderson
9Center for Neurodegenerative Science, Van Andel Institute, Grand Rapids, MI 49503
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Michael X. Henderson
  • For correspondence: michael.henderson@vai.org
Eli J. Cornblath
2Department of Bioengineering, School of Engineering & Applied Science
4Department of Neuroscience, Perelman School of Medicine
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Howard L. Li
1Institute on Aging and Center for Neurodegenerative Disease Research, Department of Pathology and Laboratory Medicine, Perelman School of Medicine
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Lakshmi Changolkar
1Institute on Aging and Center for Neurodegenerative Disease Research, Department of Pathology and Laboratory Medicine, Perelman School of Medicine
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Bin Zhang
1Institute on Aging and Center for Neurodegenerative Disease Research, Department of Pathology and Laboratory Medicine, Perelman School of Medicine
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Hannah J. Brown
1Institute on Aging and Center for Neurodegenerative Disease Research, Department of Pathology and Laboratory Medicine, Perelman School of Medicine
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ronald J. Gathagan
1Institute on Aging and Center for Neurodegenerative Disease Research, Department of Pathology and Laboratory Medicine, Perelman School of Medicine
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Modupe F. Olufemi
1Institute on Aging and Center for Neurodegenerative Disease Research, Department of Pathology and Laboratory Medicine, Perelman School of Medicine
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Danielle S. Bassett
2Department of Bioengineering, School of Engineering & Applied Science
3Department of Electrical & Systems Engineering, School of Engineering & Applied Science
5Department of Physics & Astronomy, College of Arts & Sciences
6Department of Psychiatry, Perelman School of Medicine
7Department of Neurology, Perelman School of Medicine University of Pennsylvania, Philadelphia, PA, 19104 USA
8Santa Fe Institute, Santa Fe, NM 87501 USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Danielle S. Bassett
John Q. Trojanowski
1Institute on Aging and Center for Neurodegenerative Disease Research, Department of Pathology and Laboratory Medicine, Perelman School of Medicine
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Virginia M.Y. Lee
1Institute on Aging and Center for Neurodegenerative Disease Research, Department of Pathology and Laboratory Medicine, Perelman School of Medicine
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Abstract
  • Full Text
  • Info/History
  • Metrics
  • Preview PDF
Loading

Article Information

doi 
https://doi.org/10.1101/2020.10.13.337857
History 
  • October 14, 2020.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Michael X. Henderson9,*,
  2. Eli J. Cornblath2,4,
  3. Howard L. Li1,
  4. Lakshmi Changolkar1,
  5. Bin Zhang1,
  6. Hannah J. Brown1,
  7. Ronald J. Gathagan1,
  8. Modupe F. Olufemi1,
  9. Danielle S. Bassett2,3,5,6,7,8,
  10. John Q. Trojanowski1 and
  11. Virginia M.Y. Lee1
  1. 1Institute on Aging and Center for Neurodegenerative Disease Research, Department of Pathology and Laboratory Medicine, Perelman School of Medicine
  2. 2Department of Bioengineering, School of Engineering & Applied Science
  3. 3Department of Electrical & Systems Engineering, School of Engineering & Applied Science
  4. 4Department of Neuroscience, Perelman School of Medicine
  5. 5Department of Physics & Astronomy, College of Arts & Sciences
  6. 6Department of Psychiatry, Perelman School of Medicine
  7. 7Department of Neurology, Perelman School of Medicine University of Pennsylvania, Philadelphia, PA, 19104 USA
  8. 8Santa Fe Institute, Santa Fe, NM 87501 USA
  9. 9Center for Neurodegenerative Science, Van Andel Institute, Grand Rapids, MI 49503
  1. ↵*Correspondence: michael.henderson{at}vai.org
Back to top
PreviousNext
Posted October 14, 2020.
Download PDF
Email

Thank you for your interest in spreading the word about bioRxiv.

NOTE: Your email address is requested solely to identify you as the sender of this article.

Enter multiple addresses on separate lines or separate them with commas.
Tau pathology spreads between anatomically-connected regions of the brain and is modulated by a LRRK2 mutation
(Your Name) has forwarded a page to you from bioRxiv
(Your Name) thought you would like to see this page from the bioRxiv website.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Share
Tau pathology spreads between anatomically-connected regions of the brain and is modulated by a LRRK2 mutation
Michael X. Henderson, Eli J. Cornblath, Howard L. Li, Lakshmi Changolkar, Bin Zhang, Hannah J. Brown, Ronald J. Gathagan, Modupe F. Olufemi, Danielle S. Bassett, John Q. Trojanowski, Virginia M.Y. Lee
bioRxiv 2020.10.13.337857; doi: https://doi.org/10.1101/2020.10.13.337857
Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
Citation Tools
Tau pathology spreads between anatomically-connected regions of the brain and is modulated by a LRRK2 mutation
Michael X. Henderson, Eli J. Cornblath, Howard L. Li, Lakshmi Changolkar, Bin Zhang, Hannah J. Brown, Ronald J. Gathagan, Modupe F. Olufemi, Danielle S. Bassett, John Q. Trojanowski, Virginia M.Y. Lee
bioRxiv 2020.10.13.337857; doi: https://doi.org/10.1101/2020.10.13.337857

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Subject Area

  • Neuroscience
Subject Areas
All Articles
  • Animal Behavior and Cognition (2430)
  • Biochemistry (4791)
  • Bioengineering (3333)
  • Bioinformatics (14684)
  • Biophysics (6640)
  • Cancer Biology (5172)
  • Cell Biology (7429)
  • Clinical Trials (138)
  • Developmental Biology (4367)
  • Ecology (6874)
  • Epidemiology (2057)
  • Evolutionary Biology (9926)
  • Genetics (7346)
  • Genomics (9533)
  • Immunology (4558)
  • Microbiology (12686)
  • Molecular Biology (4948)
  • Neuroscience (28348)
  • Paleontology (199)
  • Pathology (809)
  • Pharmacology and Toxicology (1392)
  • Physiology (2024)
  • Plant Biology (4504)
  • Scientific Communication and Education (977)
  • Synthetic Biology (1299)
  • Systems Biology (3917)
  • Zoology (726)