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Antisense oligonucleotides targeting alpha-synuclein reduce pre-formed fibril-induced Lewy pathology and improve some domains of cognitive and motor performance

Sydney Weber Boutros, Jacob Raber, Vivek K. Unni
doi: https://doi.org/10.1101/2020.10.21.349191
Sydney Weber Boutros
1Department of Behavioral Neuroscience, OHSU
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Jacob Raber
1Department of Behavioral Neuroscience, OHSU
2Department of Neurology, OHSU
3Departments of Psychiatry and Radiation Medicine, Division of Neuroscience, ONPRC, OHSU
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Vivek K. Unni
2Department of Neurology, OHSU
4Jungers Center for Neuroscience Research and OHSU Parkinson Center
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  • For correspondence: unni@ohsu.edu
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Article Information

doi 
https://doi.org/10.1101/2020.10.21.349191
History 
  • October 21, 2020.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Sydney Weber Boutros1,
  2. Jacob Raber1,2,3 and
  3. Vivek K. Unni2,4,*
  1. 1Department of Behavioral Neuroscience, OHSU
  2. 2Department of Neurology, OHSU
  3. 3Departments of Psychiatry and Radiation Medicine, Division of Neuroscience, ONPRC, OHSU
  4. 4Jungers Center for Neuroscience Research and OHSU Parkinson Center
  1. ↵*Corresponding author; email: unni{at}ohsu.edu
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Posted October 21, 2020.
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Antisense oligonucleotides targeting alpha-synuclein reduce pre-formed fibril-induced Lewy pathology and improve some domains of cognitive and motor performance
Sydney Weber Boutros, Jacob Raber, Vivek K. Unni
bioRxiv 2020.10.21.349191; doi: https://doi.org/10.1101/2020.10.21.349191
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Antisense oligonucleotides targeting alpha-synuclein reduce pre-formed fibril-induced Lewy pathology and improve some domains of cognitive and motor performance
Sydney Weber Boutros, Jacob Raber, Vivek K. Unni
bioRxiv 2020.10.21.349191; doi: https://doi.org/10.1101/2020.10.21.349191

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