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Antisense oligonucleotides targeting alpha-synuclein reduce pre-formed fibril-induced Lewy pathology and improve some domains of cognitive and motor performance

Sydney Weber Boutros, Jacob Raber, Vivek K. Unni
doi: https://doi.org/10.1101/2020.10.21.349191
Sydney Weber Boutros
1Department of Behavioral Neuroscience, OHSU
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Jacob Raber
1Department of Behavioral Neuroscience, OHSU
2Department of Neurology, OHSU
3Departments of Psychiatry and Radiation Medicine, Division of Neuroscience, ONPRC, OHSU
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Vivek K. Unni
2Department of Neurology, OHSU
4Jungers Center for Neuroscience Research and OHSU Parkinson Center
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  • For correspondence: unni@ohsu.edu
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Posted October 21, 2020.
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Antisense oligonucleotides targeting alpha-synuclein reduce pre-formed fibril-induced Lewy pathology and improve some domains of cognitive and motor performance
Sydney Weber Boutros, Jacob Raber, Vivek K. Unni
bioRxiv 2020.10.21.349191; doi: https://doi.org/10.1101/2020.10.21.349191
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Antisense oligonucleotides targeting alpha-synuclein reduce pre-formed fibril-induced Lewy pathology and improve some domains of cognitive and motor performance
Sydney Weber Boutros, Jacob Raber, Vivek K. Unni
bioRxiv 2020.10.21.349191; doi: https://doi.org/10.1101/2020.10.21.349191

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