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A β-catenin-driven switch in TCF/LEF transcription factor binding to DNA target sites promotes commitment of mammalian nephron progenitor cells
View ORCID ProfileQiuyu Guo, Albert Kim, Bin Li, Andrew Ransick, Helena Bugacov, Xi Chen, Nils Lindstrom, Aaron Brown, View ORCID ProfileLeif Oxburgh, View ORCID ProfileBing Ren, View ORCID ProfileAndrew P. McMahon
doi: https://doi.org/10.1101/2020.10.26.356410
Qiuyu Guo
1Department of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad-CIRM Center for Regenerative Medicine and Stem Cell Research, Keck School of Medicine of the University of Southern California, CA 90089, USA
Albert Kim
1Department of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad-CIRM Center for Regenerative Medicine and Stem Cell Research, Keck School of Medicine of the University of Southern California, CA 90089, USA
Bin Li
3The Rogosin Institute, New York, NY, 10065, USA
Andrew Ransick
1Department of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad-CIRM Center for Regenerative Medicine and Stem Cell Research, Keck School of Medicine of the University of Southern California, CA 90089, USA
Helena Bugacov
1Department of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad-CIRM Center for Regenerative Medicine and Stem Cell Research, Keck School of Medicine of the University of Southern California, CA 90089, USA
Xi Chen
1Department of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad-CIRM Center for Regenerative Medicine and Stem Cell Research, Keck School of Medicine of the University of Southern California, CA 90089, USA
Nils Lindstrom
1Department of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad-CIRM Center for Regenerative Medicine and Stem Cell Research, Keck School of Medicine of the University of Southern California, CA 90089, USA
Aaron Brown
2Center for Molecular Medicine, Maine Medical Center Research Institute, 81 Research Drive, Scarborough, ME 04074, USA
Leif Oxburgh
3The Rogosin Institute, New York, NY, 10065, USA
Bing Ren
4Ludwig Institute for Cancer Research, Department of Cellular and Molecular Medicine, Institute of Genomic Medicine, Moores Cancer Center, University of California San Diego, La Jolla, California, United States of America
Andrew P. McMahon
1Department of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad-CIRM Center for Regenerative Medicine and Stem Cell Research, Keck School of Medicine of the University of Southern California, CA 90089, USA
Article usage
Posted October 28, 2020.
A β-catenin-driven switch in TCF/LEF transcription factor binding to DNA target sites promotes commitment of mammalian nephron progenitor cells
Qiuyu Guo, Albert Kim, Bin Li, Andrew Ransick, Helena Bugacov, Xi Chen, Nils Lindstrom, Aaron Brown, Leif Oxburgh, Bing Ren, Andrew P. McMahon
bioRxiv 2020.10.26.356410; doi: https://doi.org/10.1101/2020.10.26.356410
A β-catenin-driven switch in TCF/LEF transcription factor binding to DNA target sites promotes commitment of mammalian nephron progenitor cells
Qiuyu Guo, Albert Kim, Bin Li, Andrew Ransick, Helena Bugacov, Xi Chen, Nils Lindstrom, Aaron Brown, Leif Oxburgh, Bing Ren, Andrew P. McMahon
bioRxiv 2020.10.26.356410; doi: https://doi.org/10.1101/2020.10.26.356410
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