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SARS-CoV-2 spike D614G variant confers enhanced replication and transmissibility
Bin Zhou, Tran Thi Nhu Thao, Donata Hoffmann, Adriano Taddeo, Nadine Ebert, Fabien Labroussaa, Anne Pohlmann, Jacqueline King, Jasmine Portmann, Nico Joel Halwe, Lorenz Ulrich, Bettina Salome Trüeb, Jenna N. Kelly, Xiaoyu Fan, Bernd Hoffmann, Silvio Steiner, Li Wang, Lisa Thomann, Xudong Lin, Hanspeter Stalder, Berta Pozzi, Simone de Brot, Nannan Jiang, Dan Cui, Jaber Hossain, Malania Wilson, Matthew Keller, Thomas J. Stark, John R. Barnes, View ORCID ProfileRonald Dijkman, Joerg Jores, Charaf Benarafa, David E. Wentworth, Volker Thiel, Martin Beer
doi: https://doi.org/10.1101/2020.10.27.357558
Bin Zhou
1CDC COVID-19 Response, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
Tran Thi Nhu Thao
2Institute of Virology and Immunology (IVI), Bern and Mittelhäusern, Switzerland
3Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland
4Graduate School for Biomedical Science, University of Bern, Bern, Switzerland
Donata Hoffmann
5Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany
Adriano Taddeo
2Institute of Virology and Immunology (IVI), Bern and Mittelhäusern, Switzerland
3Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland
Nadine Ebert
2Institute of Virology and Immunology (IVI), Bern and Mittelhäusern, Switzerland
3Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland
Fabien Labroussaa
3Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland
6Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern, Bern, Switzerland
Anne Pohlmann
5Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany
Jacqueline King
5Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany
Jasmine Portmann
2Institute of Virology and Immunology (IVI), Bern and Mittelhäusern, Switzerland
3Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland
Nico Joel Halwe
5Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany
Lorenz Ulrich
5Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany
Bettina Salome Trüeb
3Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland
6Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern, Bern, Switzerland
Jenna N. Kelly
2Institute of Virology and Immunology (IVI), Bern and Mittelhäusern, Switzerland
3Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland
Xiaoyu Fan
1CDC COVID-19 Response, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
Bernd Hoffmann
5Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany
Silvio Steiner
2Institute of Virology and Immunology (IVI), Bern and Mittelhäusern, Switzerland
3Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland
4Graduate School for Biomedical Science, University of Bern, Bern, Switzerland
Li Wang
1CDC COVID-19 Response, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
Lisa Thomann
2Institute of Virology and Immunology (IVI), Bern and Mittelhäusern, Switzerland
3Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland
Xudong Lin
7Battelle Memorial Institute, Atlanta, Georgia, United States of America
Hanspeter Stalder
2Institute of Virology and Immunology (IVI), Bern and Mittelhäusern, Switzerland
3Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland
Berta Pozzi
8Institute of Cell Biology, University of Bern, Bern, Switzerland
Simone de Brot
9COMPATH, Institute of Animal Pathology, University of Bern, Bern, Switzerland
Nannan Jiang
10Oak Ridge Institute for Science and Education, Oak Ridge, Tennessee, United States of America
Dan Cui
7Battelle Memorial Institute, Atlanta, Georgia, United States of America
Jaber Hossain
1CDC COVID-19 Response, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
Malania Wilson
1CDC COVID-19 Response, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
Matthew Keller
1CDC COVID-19 Response, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
Thomas J. Stark
1CDC COVID-19 Response, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
John R. Barnes
1CDC COVID-19 Response, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
Ronald Dijkman
2Institute of Virology and Immunology (IVI), Bern and Mittelhäusern, Switzerland
3Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland
11Institute for Infectious Diseases, University of Bern, Bern, Switzerland
Joerg Jores
3Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland
6Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern, Bern, Switzerland
Charaf Benarafa
2Institute of Virology and Immunology (IVI), Bern and Mittelhäusern, Switzerland
3Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland
David E. Wentworth
1CDC COVID-19 Response, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
Volker Thiel
2Institute of Virology and Immunology (IVI), Bern and Mittelhäusern, Switzerland
3Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland
Martin Beer
5Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany
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Posted October 27, 2020.
SARS-CoV-2 spike D614G variant confers enhanced replication and transmissibility
Bin Zhou, Tran Thi Nhu Thao, Donata Hoffmann, Adriano Taddeo, Nadine Ebert, Fabien Labroussaa, Anne Pohlmann, Jacqueline King, Jasmine Portmann, Nico Joel Halwe, Lorenz Ulrich, Bettina Salome Trüeb, Jenna N. Kelly, Xiaoyu Fan, Bernd Hoffmann, Silvio Steiner, Li Wang, Lisa Thomann, Xudong Lin, Hanspeter Stalder, Berta Pozzi, Simone de Brot, Nannan Jiang, Dan Cui, Jaber Hossain, Malania Wilson, Matthew Keller, Thomas J. Stark, John R. Barnes, Ronald Dijkman, Joerg Jores, Charaf Benarafa, David E. Wentworth, Volker Thiel, Martin Beer
bioRxiv 2020.10.27.357558; doi: https://doi.org/10.1101/2020.10.27.357558
SARS-CoV-2 spike D614G variant confers enhanced replication and transmissibility
Bin Zhou, Tran Thi Nhu Thao, Donata Hoffmann, Adriano Taddeo, Nadine Ebert, Fabien Labroussaa, Anne Pohlmann, Jacqueline King, Jasmine Portmann, Nico Joel Halwe, Lorenz Ulrich, Bettina Salome Trüeb, Jenna N. Kelly, Xiaoyu Fan, Bernd Hoffmann, Silvio Steiner, Li Wang, Lisa Thomann, Xudong Lin, Hanspeter Stalder, Berta Pozzi, Simone de Brot, Nannan Jiang, Dan Cui, Jaber Hossain, Malania Wilson, Matthew Keller, Thomas J. Stark, John R. Barnes, Ronald Dijkman, Joerg Jores, Charaf Benarafa, David E. Wentworth, Volker Thiel, Martin Beer
bioRxiv 2020.10.27.357558; doi: https://doi.org/10.1101/2020.10.27.357558
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