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Saracatinib is an efficacious clinical candidate for fibrodysplasia ossificans progressiva
Eleanor Williams, Jana Bagarova, Georgina Kerr, Dong-Dong Xia, Elsie S. Place, Devaveena Dey, Yue Shen, Geoffrey A. Bocobo, Agustin H. Mohedas, Xiuli Huang, Philip E. Sanderson, Arthur Lee, Wei Zheng, View ORCID ProfileAris N. Economides, James C. Smith, View ORCID ProfilePaul B. Yu, View ORCID ProfileAlex N. Bullock
doi: https://doi.org/10.1101/2020.10.29.360370
Eleanor Williams
1Centre for Medicines Discovery, University of Oxford, Oxford OX3 7DQ, UK
Jana Bagarova
2Department of Medicine, Cardiovascular Division, Brigham and Women’s Hospital, Harvard Medical School, 75 Francis St., Boston, MA 02115, USA
Georgina Kerr
1Centre for Medicines Discovery, University of Oxford, Oxford OX3 7DQ, UK
Dong-Dong Xia
2Department of Medicine, Cardiovascular Division, Brigham and Women’s Hospital, Harvard Medical School, 75 Francis St., Boston, MA 02115, USA
Elsie S. Place
3Developmental Biology Laboratory, Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK
Devaveena Dey
2Department of Medicine, Cardiovascular Division, Brigham and Women’s Hospital, Harvard Medical School, 75 Francis St., Boston, MA 02115, USA
Yue Shen
2Department of Medicine, Cardiovascular Division, Brigham and Women’s Hospital, Harvard Medical School, 75 Francis St., Boston, MA 02115, USA
Geoffrey A. Bocobo
2Department of Medicine, Cardiovascular Division, Brigham and Women’s Hospital, Harvard Medical School, 75 Francis St., Boston, MA 02115, USA
Agustin H. Mohedas
2Department of Medicine, Cardiovascular Division, Brigham and Women’s Hospital, Harvard Medical School, 75 Francis St., Boston, MA 02115, USA
Xiuli Huang
4National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD 20892, USA
Philip E. Sanderson
4National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD 20892, USA
Arthur Lee
4National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD 20892, USA
Wei Zheng
4National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD 20892, USA
Aris N. Economides
5Regeneron Pharmaceuticals Inc., 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA
James C. Smith
3Developmental Biology Laboratory, Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK
Paul B. Yu
2Department of Medicine, Cardiovascular Division, Brigham and Women’s Hospital, Harvard Medical School, 75 Francis St., Boston, MA 02115, USA
Alex N. Bullock
1Centre for Medicines Discovery, University of Oxford, Oxford OX3 7DQ, UK
Posted October 29, 2020.
Saracatinib is an efficacious clinical candidate for fibrodysplasia ossificans progressiva
Eleanor Williams, Jana Bagarova, Georgina Kerr, Dong-Dong Xia, Elsie S. Place, Devaveena Dey, Yue Shen, Geoffrey A. Bocobo, Agustin H. Mohedas, Xiuli Huang, Philip E. Sanderson, Arthur Lee, Wei Zheng, Aris N. Economides, James C. Smith, Paul B. Yu, Alex N. Bullock
bioRxiv 2020.10.29.360370; doi: https://doi.org/10.1101/2020.10.29.360370
Saracatinib is an efficacious clinical candidate for fibrodysplasia ossificans progressiva
Eleanor Williams, Jana Bagarova, Georgina Kerr, Dong-Dong Xia, Elsie S. Place, Devaveena Dey, Yue Shen, Geoffrey A. Bocobo, Agustin H. Mohedas, Xiuli Huang, Philip E. Sanderson, Arthur Lee, Wei Zheng, Aris N. Economides, James C. Smith, Paul B. Yu, Alex N. Bullock
bioRxiv 2020.10.29.360370; doi: https://doi.org/10.1101/2020.10.29.360370
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