New Results
Sex-biased ZRSR2 mutations in myeloid malignancies impair plasmacytoid dendritic cell activation and apoptosis
Katsuhiro Togami, Sun Sook Chung, Vikas Madan, Christopher M. Kenyon, Lucia Cabal-Hierro, Justin Taylor, Sunhee S. Kim, Gabriel K. Griffin, Mahmoud Ghandi, Jia Li, Yvonne Y. Li, Fanny Angelot-Delettre, Sabeha Biichle, Michael Seiler, Silvia Buonamici, Scott B. Lovitch, Abner Louissaint Jr., Elizabeth A. Morgan, Fabrice Jardin, Pier Paolo Piccaluga, David M. Weinstock, Peter S. Hammerman, Henry Yang, Marina Konopleva, Naveen Pemmaraju, Francine Garnache-Ottou, Omar Abdel-Wahab, H. Phillip Koeffler, View ORCID ProfileAndrew A. Lane
doi: https://doi.org/10.1101/2020.10.29.360503
Katsuhiro Togami
1Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA
Sun Sook Chung
1Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA
Vikas Madan
2Cancer Science Institute of Singapore, National University of Singapore, Singapore
Christopher M. Kenyon
1Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA
Lucia Cabal-Hierro
1Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA
Justin Taylor
3Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY
4Division of Hematology, Department of Medicine, Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, Miami, FL
Sunhee S. Kim
1Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA
Gabriel K. Griffin
5Department of Pathology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA
6Broad Institute of Harvard and MIT, Cambridge, MA
Mahmoud Ghandi
6Broad Institute of Harvard and MIT, Cambridge, MA
Jia Li
2Cancer Science Institute of Singapore, National University of Singapore, Singapore
Yvonne Y. Li
1Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA
Fanny Angelot-Delettre
7University of Bourgogne Franche-Comté, INSERM, EFS BFC, UMR1098, Interactions Hôte-Greffon-Tumeur/Ingénierie Cellulaire et Génique, Besançon, France
Sabeha Biichle
7University of Bourgogne Franche-Comté, INSERM, EFS BFC, UMR1098, Interactions Hôte-Greffon-Tumeur/Ingénierie Cellulaire et Génique, Besançon, France
Michael Seiler
8H3 Biomedicine, Cambridge, MA
Silvia Buonamici
8H3 Biomedicine, Cambridge, MA
Scott B. Lovitch
5Department of Pathology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA
Abner Louissaint Jr.
9Department of Pathology, Massachusetts General Hospital, Boston, MA
Elizabeth A. Morgan
5Department of Pathology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA
Fabrice Jardin
10Inserm U1245, Centre Henri Becquerel, Université de Rouen, IRIB, Rouen, France
Pier Paolo Piccaluga
11Department of Experimental, Diagnostic, and Specialty Medicine, Bologna University Medical School, Bologna, Italy
12Department of Biomolecular Strategies, Genetics, Avant-Garde Therapies and Neurosciences (SBGN), Euro-Mediterranean Institute of Science and Technology (IEMEST), Palermo, Italy
13School of Health, Department of Pathology, Jomo Kenyatta University of Agriculture and Technology, Nairobi, Kenya
David M. Weinstock
1Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA
6Broad Institute of Harvard and MIT, Cambridge, MA
Peter S. Hammerman
1Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA
Henry Yang
2Cancer Science Institute of Singapore, National University of Singapore, Singapore
Marina Konopleva
14Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX
Naveen Pemmaraju
14Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX
Francine Garnache-Ottou
7University of Bourgogne Franche-Comté, INSERM, EFS BFC, UMR1098, Interactions Hôte-Greffon-Tumeur/Ingénierie Cellulaire et Génique, Besançon, France
Omar Abdel-Wahab
3Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY
H. Phillip Koeffler
2Cancer Science Institute of Singapore, National University of Singapore, Singapore
15Cedars-Sinai Medical Center, Division of Hematology/Oncology, UCLA School of Medicine, Los Angeles, CA
16Department of Hematology-Oncology, National University Cancer Institute of Singapore (NCIS), National University Hospital, Singapore
Andrew A. Lane
1Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA
6Broad Institute of Harvard and MIT, Cambridge, MA
17Ludwig Center at Harvard, Boston, MA
Article usage
Posted October 29, 2020.
Sex-biased ZRSR2 mutations in myeloid malignancies impair plasmacytoid dendritic cell activation and apoptosis
Katsuhiro Togami, Sun Sook Chung, Vikas Madan, Christopher M. Kenyon, Lucia Cabal-Hierro, Justin Taylor, Sunhee S. Kim, Gabriel K. Griffin, Mahmoud Ghandi, Jia Li, Yvonne Y. Li, Fanny Angelot-Delettre, Sabeha Biichle, Michael Seiler, Silvia Buonamici, Scott B. Lovitch, Abner Louissaint Jr., Elizabeth A. Morgan, Fabrice Jardin, Pier Paolo Piccaluga, David M. Weinstock, Peter S. Hammerman, Henry Yang, Marina Konopleva, Naveen Pemmaraju, Francine Garnache-Ottou, Omar Abdel-Wahab, H. Phillip Koeffler, Andrew A. Lane
bioRxiv 2020.10.29.360503; doi: https://doi.org/10.1101/2020.10.29.360503
Sex-biased ZRSR2 mutations in myeloid malignancies impair plasmacytoid dendritic cell activation and apoptosis
Katsuhiro Togami, Sun Sook Chung, Vikas Madan, Christopher M. Kenyon, Lucia Cabal-Hierro, Justin Taylor, Sunhee S. Kim, Gabriel K. Griffin, Mahmoud Ghandi, Jia Li, Yvonne Y. Li, Fanny Angelot-Delettre, Sabeha Biichle, Michael Seiler, Silvia Buonamici, Scott B. Lovitch, Abner Louissaint Jr., Elizabeth A. Morgan, Fabrice Jardin, Pier Paolo Piccaluga, David M. Weinstock, Peter S. Hammerman, Henry Yang, Marina Konopleva, Naveen Pemmaraju, Francine Garnache-Ottou, Omar Abdel-Wahab, H. Phillip Koeffler, Andrew A. Lane
bioRxiv 2020.10.29.360503; doi: https://doi.org/10.1101/2020.10.29.360503
Subject Area
Subject Areas
- Biochemistry (11753)
- Bioengineering (8752)
- Bioinformatics (29201)
- Biophysics (14974)
- Cancer Biology (12100)
- Cell Biology (17413)
- Clinical Trials (138)
- Developmental Biology (9422)
- Ecology (14182)
- Epidemiology (2067)
- Evolutionary Biology (18309)
- Genetics (12245)
- Genomics (16804)
- Immunology (11869)
- Microbiology (28098)
- Molecular Biology (11596)
- Neuroscience (60975)
- Paleontology (451)
- Pathology (1871)
- Pharmacology and Toxicology (3238)
- Physiology (4959)
- Plant Biology (10427)
- Synthetic Biology (2886)
- Systems Biology (7340)
- Zoology (1651)