Skip to main content
bioRxiv
  • Home
  • About
  • Submit
  • ALERTS / RSS
Advanced Search
New Results

Assessment of transparency indicators across the biomedical literature: how open is open?

View ORCID ProfileStylianos Serghiou, View ORCID ProfileDespina G. Contopoulos-Ioannidis, View ORCID ProfileKevin W. Boyack, View ORCID ProfileNico Riedel, View ORCID ProfileJoshua D. Wallach, View ORCID ProfileJohn P. A. Ioannidis
doi: https://doi.org/10.1101/2020.10.30.361618
Stylianos Serghiou
1Department of Population Health and Epidemiology, Stanford University School of Medicine, Stanford, CA, USA
2Meta-Research Innovation Center at Stanford (METRICS), Stanford School of Medicine, 1265 Welch Rd, MSOB X306, Stanford, CA, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Stylianos Serghiou
Despina G. Contopoulos-Ioannidis
3Division of Infectious Diseases, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Despina G. Contopoulos-Ioannidis
Kevin W. Boyack
4SciTech Strategies, Inc., Albuquerque, NM, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Kevin W. Boyack
Nico Riedel
5Berlin Institute of Health, QUEST - Center for Transforming Biomedical Research, Berlin, Germany
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Nico Riedel
Joshua D. Wallach
6Department of Environmental Health Sciences, Yale School of Public Health, 60 College Street, 4th Floor, Room 411, New Haven, CT, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Joshua D. Wallach
John P. A. Ioannidis
1Department of Population Health and Epidemiology, Stanford University School of Medicine, Stanford, CA, USA
2Meta-Research Innovation Center at Stanford (METRICS), Stanford School of Medicine, 1265 Welch Rd, MSOB X306, Stanford, CA, USA
7Stanford Prevention Research Center, Department of Medicine, Stanford University School of Medicine, 1265 Welch Rd, MSOB X306, Stanford, CA, USA
8Department of Biomedical Data Science, Stanford University School of Medicine, Stanford, CA 94305, USA
9Department of Statistics, Stanford University School of Humanities and Sciences, Stanford, CA, 94305, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for John P. A. Ioannidis
  • For correspondence: jioannid@stanford.edu
  • Abstract
  • Full Text
  • Info/History
  • Metrics
  • Supplementary material
  • Data/Code
  • Preview PDF
Loading

Abstract

Recent concerns about the reproducibility of science have led to several calls for more open and transparent research practices and for the monitoring of potential improvements over time. However, with tens of thousands of new biomedical articles published per week, manually mapping and monitoring changes in transparency is unrealistic. We present an open-source, automated approach to identify five indicators of transparency (data sharing, code sharing, conflicts of interest disclosures, funding disclosures and protocol registration) and apply it across the entire open access biomedical literature of 2.75 million articles on PubMed Central. Our results indicate remarkable improvements in some (e.g. conflict of interest disclosures, funding disclosures), but not other (e.g. protocol registration, code sharing) areas of transparency over time, and map transparency across fields of science, countries, journals and publishers. This work has enabled the creation of a large, integrated, and openly available database to expedite further efforts to monitor, understand and promote transparency and reproducibility in science.

Competing Interest Statement

The authors have declared no competing interest.

Footnotes

  • Funding disclosure Funded by National Institutes of Health award HHSN271201800033C. METRICS has also been supported by grants from the Laura and John Arnold Foundation. S.S. has been funded by the Department of Epidemiology and Population Health at Stanford University and as a Scholar of the Stanford Data Science Initiative. In the past 36 months, J.D.W. received research support through the Collaboration for Research Integrity and Transparency from the Laura and John Arnold Foundation and through the Center for Excellence in Regulatory Science and Innovation (CERSI) at Yale University and the Mayo Clinic (U01FD005938).

  • Competing interest declaration We declare no competing interests.

  • https://github.com/serghiou/transparency-indicators

  • https://osf.io/e58ws/

Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.
Back to top
PreviousNext
Posted October 30, 2020.
Download PDF

Supplementary Material

Data/Code
Email

Thank you for your interest in spreading the word about bioRxiv.

NOTE: Your email address is requested solely to identify you as the sender of this article.

Enter multiple addresses on separate lines or separate them with commas.
Assessment of transparency indicators across the biomedical literature: how open is open?
(Your Name) has forwarded a page to you from bioRxiv
(Your Name) thought you would like to see this page from the bioRxiv website.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Share
Assessment of transparency indicators across the biomedical literature: how open is open?
Stylianos Serghiou, Despina G. Contopoulos-Ioannidis, Kevin W. Boyack, Nico Riedel, Joshua D. Wallach, John P. A. Ioannidis
bioRxiv 2020.10.30.361618; doi: https://doi.org/10.1101/2020.10.30.361618
Reddit logo Twitter logo Facebook logo LinkedIn logo Mendeley logo
Citation Tools
Assessment of transparency indicators across the biomedical literature: how open is open?
Stylianos Serghiou, Despina G. Contopoulos-Ioannidis, Kevin W. Boyack, Nico Riedel, Joshua D. Wallach, John P. A. Ioannidis
bioRxiv 2020.10.30.361618; doi: https://doi.org/10.1101/2020.10.30.361618

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Subject Area

  • Scientific Communication and Education
Subject Areas
All Articles
  • Animal Behavior and Cognition (4237)
  • Biochemistry (9148)
  • Bioengineering (6786)
  • Bioinformatics (24025)
  • Biophysics (12137)
  • Cancer Biology (9545)
  • Cell Biology (13795)
  • Clinical Trials (138)
  • Developmental Biology (7642)
  • Ecology (11716)
  • Epidemiology (2066)
  • Evolutionary Biology (15518)
  • Genetics (10650)
  • Genomics (14332)
  • Immunology (9493)
  • Microbiology (22858)
  • Molecular Biology (9103)
  • Neuroscience (49033)
  • Paleontology (355)
  • Pathology (1484)
  • Pharmacology and Toxicology (2572)
  • Physiology (3849)
  • Plant Biology (8338)
  • Scientific Communication and Education (1472)
  • Synthetic Biology (2296)
  • Systems Biology (6196)
  • Zoology (1302)