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Global regulatory transitions at core promoters demarcate the mammalian germline cycle

View ORCID ProfileNevena Cvetesic, View ORCID ProfileMalgorzata Borkowska, View ORCID ProfileYuki Hatanaka, View ORCID ProfileHarry G. Leitch, View ORCID ProfileFerenc Müller, View ORCID ProfileChangwei Yu, View ORCID ProfileStéphane D. Vincent, View ORCID ProfileLászló Tora, View ORCID ProfilePetra Hajkova, View ORCID ProfileBoris Lenhard
doi: https://doi.org/10.1101/2020.10.30.361865
Nevena Cvetesic
1Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London W12 0NN, UK
2MRC London Institute of Medical Sciences, London W12 0NN, UK
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  • ORCID record for Nevena Cvetesic
  • For correspondence: ncvetesi@ic.ac.uk petra.hajkova@lms.mrc.ac.uk b.lenhard@imperial.ac.uk
Malgorzata Borkowska
1Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London W12 0NN, UK
2MRC London Institute of Medical Sciences, London W12 0NN, UK
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  • ORCID record for Malgorzata Borkowska
Yuki Hatanaka
1Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London W12 0NN, UK
2MRC London Institute of Medical Sciences, London W12 0NN, UK
3Bioresource Engineering Division, RIKEN BioResource Research Center, 305-0074 Ibaraki, Japan
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  • ORCID record for Yuki Hatanaka
Harry G. Leitch
1Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London W12 0NN, UK
2MRC London Institute of Medical Sciences, London W12 0NN, UK
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Ferenc Müller
4Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Edgbaston B15 2TT, UK
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  • ORCID record for Ferenc Müller
Changwei Yu
5Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France
6Centre National de la Recherche Scientifique (CNRS), UMR7104, Illkirch, France
7Institut National de la Santé et de la Recherche Médicale (INSERM), U1258, Illkirch, France
8Université de Strasbourg, Illkirch, France
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Stéphane D. Vincent
5Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France
6Centre National de la Recherche Scientifique (CNRS), UMR7104, Illkirch, France
7Institut National de la Santé et de la Recherche Médicale (INSERM), U1258, Illkirch, France
8Université de Strasbourg, Illkirch, France
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László Tora
5Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France
6Centre National de la Recherche Scientifique (CNRS), UMR7104, Illkirch, France
7Institut National de la Santé et de la Recherche Médicale (INSERM), U1258, Illkirch, France
8Université de Strasbourg, Illkirch, France
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Petra Hajkova
1Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London W12 0NN, UK
2MRC London Institute of Medical Sciences, London W12 0NN, UK
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  • For correspondence: ncvetesi@ic.ac.uk petra.hajkova@lms.mrc.ac.uk b.lenhard@imperial.ac.uk
Boris Lenhard
1Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London W12 0NN, UK
2MRC London Institute of Medical Sciences, London W12 0NN, UK
9Sars International Centre for Marine Molecular Biology, University of Bergen, N-5008 Bergen, Norway
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  • For correspondence: ncvetesi@ic.ac.uk petra.hajkova@lms.mrc.ac.uk b.lenhard@imperial.ac.uk
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Article Information

doi 
https://doi.org/10.1101/2020.10.30.361865
History 
  • October 30, 2020.

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The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.

Author Information

  1. Nevena Cvetesic1,2,*,
  2. Malgorzata Borkowska1,2,**,
  3. Yuki Hatanaka1,2,3,**,
  4. Harry G. Leitch1,2,
  5. Ferenc Müller4,
  6. Changwei Yu5,6,7,8,
  7. Stéphane D. Vincent5,6,7,8,
  8. László Tora5,6,7,8,
  9. Petra Hajkova1,2,* and
  10. Boris Lenhard1,2,9,*
  1. 1Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London W12 0NN, UK
  2. 2MRC London Institute of Medical Sciences, London W12 0NN, UK
  3. 3Bioresource Engineering Division, RIKEN BioResource Research Center, 305-0074 Ibaraki, Japan
  4. 4Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Edgbaston B15 2TT, UK
  5. 5Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France
  6. 6Centre National de la Recherche Scientifique (CNRS), UMR7104, Illkirch, France
  7. 7Institut National de la Santé et de la Recherche Médicale (INSERM), U1258, Illkirch, France
  8. 8Université de Strasbourg, Illkirch, France
  9. 9Sars International Centre for Marine Molecular Biology, University of Bergen, N-5008 Bergen, Norway
  1. ↵*Correspondence should be addressed to N.C. ncvetesi{at}ic.ac.uk, P.H. petra.hajkova{at}lms.mrc.ac.uk or B.L. b.lenhard{at}imperial.ac.uk.
  1. ↵** These authors contributed equally to this work.

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Global regulatory transitions at core promoters demarcate the mammalian germline cycle
Nevena Cvetesic, Malgorzata Borkowska, Yuki Hatanaka, Harry G. Leitch, Ferenc Müller, Changwei Yu, Stéphane D. Vincent, László Tora, Petra Hajkova, Boris Lenhard
bioRxiv 2020.10.30.361865; doi: https://doi.org/10.1101/2020.10.30.361865
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Global regulatory transitions at core promoters demarcate the mammalian germline cycle
Nevena Cvetesic, Malgorzata Borkowska, Yuki Hatanaka, Harry G. Leitch, Ferenc Müller, Changwei Yu, Stéphane D. Vincent, László Tora, Petra Hajkova, Boris Lenhard
bioRxiv 2020.10.30.361865; doi: https://doi.org/10.1101/2020.10.30.361865

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