New Results
Landscape analysis of escape variants identifies SARS-CoV-2 spike mutations that attenuate monoclonal and serum antibody neutralization
View ORCID ProfileZhuoming Liu, Laura A. VanBlargan, Louis-Marie Bloyet, View ORCID ProfilePaul W. Rothlauf, Rita E. Chen, Spencer Stumpf, Haiyan Zhao, John M. Errico, View ORCID ProfileElitza S. Theel, Mariel J. Liebeskind, Brynn Alford, William J. Buchser, View ORCID ProfileAli H. Ellebedy, View ORCID ProfileDaved H. Fremont, View ORCID ProfileMichael S. Diamond, View ORCID ProfileSean P. J. Whelan
doi: https://doi.org/10.1101/2020.11.06.372037
Zhuoming Liu
1Department of Molecular Microbiology, Harvard Medical School, Boston MA
Laura A. VanBlargan
2Department of Medicine, Harvard Medical School, Boston MA
Louis-Marie Bloyet
1Department of Molecular Microbiology, Harvard Medical School, Boston MA
Paul W. Rothlauf
1Department of Molecular Microbiology, Harvard Medical School, Boston MA
3School of Medicine, Washington University in St. Louis. Program in Virology, Harvard Medical School, Boston MA
Rita E. Chen
2Department of Medicine, Harvard Medical School, Boston MA
4Department of Pathology & Immunology, Harvard Medical School, Boston MA
Spencer Stumpf
1Department of Molecular Microbiology, Harvard Medical School, Boston MA
Haiyan Zhao
4Department of Pathology & Immunology, Harvard Medical School, Boston MA
John M. Errico
4Department of Pathology & Immunology, Harvard Medical School, Boston MA
Elitza S. Theel
5Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN
Mariel J. Liebeskind
6Department of Genetics, Harvard Medical School, Boston MA
Brynn Alford
1Department of Molecular Microbiology, Harvard Medical School, Boston MA
William J. Buchser
6Department of Genetics, Harvard Medical School, Boston MA
Ali H. Ellebedy
1Department of Molecular Microbiology, Harvard Medical School, Boston MA
4Department of Pathology & Immunology, Harvard Medical School, Boston MA
Daved H. Fremont
4Department of Pathology & Immunology, Harvard Medical School, Boston MA
Michael S. Diamond
1Department of Molecular Microbiology, Harvard Medical School, Boston MA
2Department of Medicine, Harvard Medical School, Boston MA
4Department of Pathology & Immunology, Harvard Medical School, Boston MA
Sean P. J. Whelan
1Department of Molecular Microbiology, Harvard Medical School, Boston MA
Article usage
Posted January 11, 2021.
Landscape analysis of escape variants identifies SARS-CoV-2 spike mutations that attenuate monoclonal and serum antibody neutralization
Zhuoming Liu, Laura A. VanBlargan, Louis-Marie Bloyet, Paul W. Rothlauf, Rita E. Chen, Spencer Stumpf, Haiyan Zhao, John M. Errico, Elitza S. Theel, Mariel J. Liebeskind, Brynn Alford, William J. Buchser, Ali H. Ellebedy, Daved H. Fremont, Michael S. Diamond, Sean P. J. Whelan
bioRxiv 2020.11.06.372037; doi: https://doi.org/10.1101/2020.11.06.372037
Landscape analysis of escape variants identifies SARS-CoV-2 spike mutations that attenuate monoclonal and serum antibody neutralization
Zhuoming Liu, Laura A. VanBlargan, Louis-Marie Bloyet, Paul W. Rothlauf, Rita E. Chen, Spencer Stumpf, Haiyan Zhao, John M. Errico, Elitza S. Theel, Mariel J. Liebeskind, Brynn Alford, William J. Buchser, Ali H. Ellebedy, Daved H. Fremont, Michael S. Diamond, Sean P. J. Whelan
bioRxiv 2020.11.06.372037; doi: https://doi.org/10.1101/2020.11.06.372037
Subject Area
Subject Areas
- Biochemistry (11739)
- Bioengineering (8750)
- Bioinformatics (29189)
- Biophysics (14967)
- Cancer Biology (12093)
- Cell Biology (17409)
- Clinical Trials (138)
- Developmental Biology (9419)
- Ecology (14178)
- Epidemiology (2067)
- Evolutionary Biology (18301)
- Genetics (12238)
- Genomics (16797)
- Immunology (11865)
- Microbiology (28068)
- Molecular Biology (11583)
- Neuroscience (60953)
- Paleontology (451)
- Pathology (1870)
- Pharmacology and Toxicology (3238)
- Physiology (4957)
- Plant Biology (10425)
- Synthetic Biology (2884)
- Systems Biology (7338)
- Zoology (1651)