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Amplification, not spreading limits rate of tau aggregate accumulation in Alzheimer’s disease
View ORCID ProfileGeorg Meisl, View ORCID ProfileYukun Zuo, Kieren Allinson, Timothy Rittman, Sarah DeVos, Justin S. Sanchez, Catherine K Xu, Karen E Duff, Keith A. Johnson, James B Rowe, Bradley T Hyman, Tuomas P J Knowles, David Klenerman
doi: https://doi.org/10.1101/2020.11.16.384727
Georg Meisl
1Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK
Yukun Zuo
1Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK
Kieren Allinson
2Department of Clinical Neurosciences, University of Cambridge, Biomedical Campus, Cambridge, CB2 0QQ, UK
Timothy Rittman
2Department of Clinical Neurosciences, University of Cambridge, Biomedical Campus, Cambridge, CB2 0QQ, UK
Sarah DeVos
3Department of Neurology, Harvard Medical School, MassGeneral Institute for Neuro-degenerative Disease, Massachusetts General Hospital, Charlestown, MA 02114, USA
Justin S. Sanchez
3Department of Neurology, Harvard Medical School, MassGeneral Institute for Neuro-degenerative Disease, Massachusetts General Hospital, Charlestown, MA 02114, USA
Catherine K Xu
1Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK
Karen E Duff
4Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY 10032, USA
Keith A. Johnson
3Department of Neurology, Harvard Medical School, MassGeneral Institute for Neuro-degenerative Disease, Massachusetts General Hospital, Charlestown, MA 02114, USA
James B Rowe
2Department of Clinical Neurosciences, University of Cambridge, Biomedical Campus, Cambridge, CB2 0QQ, UK
Bradley T Hyman
3Department of Neurology, Harvard Medical School, MassGeneral Institute for Neuro-degenerative Disease, Massachusetts General Hospital, Charlestown, MA 02114, USA
Tuomas P J Knowles
1Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK
5Cavendish Laboratory, University of Cambridge, 19 JJ Thomson Avenue, Cambridge, CB3 0HE, UK
David Klenerman
1Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK
6UK Dementia Research Institute, University of Cambridge, Cambridge, CB2 0XY, UK
Article usage
Posted November 17, 2020.
Amplification, not spreading limits rate of tau aggregate accumulation in Alzheimer’s disease
Georg Meisl, Yukun Zuo, Kieren Allinson, Timothy Rittman, Sarah DeVos, Justin S. Sanchez, Catherine K Xu, Karen E Duff, Keith A. Johnson, James B Rowe, Bradley T Hyman, Tuomas P J Knowles, David Klenerman
bioRxiv 2020.11.16.384727; doi: https://doi.org/10.1101/2020.11.16.384727
Amplification, not spreading limits rate of tau aggregate accumulation in Alzheimer’s disease
Georg Meisl, Yukun Zuo, Kieren Allinson, Timothy Rittman, Sarah DeVos, Justin S. Sanchez, Catherine K Xu, Karen E Duff, Keith A. Johnson, James B Rowe, Bradley T Hyman, Tuomas P J Knowles, David Klenerman
bioRxiv 2020.11.16.384727; doi: https://doi.org/10.1101/2020.11.16.384727
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