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HTT silencing delays onset and slows progression of Huntington’s disease like phenotype: Monitoring with a novel neurovascular biomarker
Hongshuai Liu, Chuangchuang Zhang, Jiadi Xu, Jing Jin, Liam Cheng, Qian Wu, Zhiliang Wei, Peiying Liu, Hanzhang Lu, View ORCID ProfilePeter C. M. van Zijl, Christopher A. Ross, View ORCID ProfileJun Hua, View ORCID ProfileWenzhen Duan
doi: https://doi.org/10.1101/2020.11.17.386631
Hongshuai Liu
1Division of Neurobiology, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of medicine, Baltimore, Maryland, USA
Chuangchuang Zhang
1Division of Neurobiology, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of medicine, Baltimore, Maryland, USA
Jiadi Xu
2F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, Maryland, USA
3The Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Jing Jin
1Division of Neurobiology, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of medicine, Baltimore, Maryland, USA
Liam Cheng
1Division of Neurobiology, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of medicine, Baltimore, Maryland, USA
Qian Wu
1Division of Neurobiology, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of medicine, Baltimore, Maryland, USA
Zhiliang Wei
3The Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Peiying Liu
3The Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Hanzhang Lu
2F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, Maryland, USA
3The Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
4Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, USA
Peter C. M. van Zijl
2F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, Maryland, USA
3The Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Christopher A. Ross
1Division of Neurobiology, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of medicine, Baltimore, Maryland, USA
5Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
6Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
7Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Jun Hua
2F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, Maryland, USA
3The Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Wenzhen Duan
1Division of Neurobiology, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of medicine, Baltimore, Maryland, USA
4Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, USA
8Program in Cellular and Molecular Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
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Posted November 19, 2020.
HTT silencing delays onset and slows progression of Huntington’s disease like phenotype: Monitoring with a novel neurovascular biomarker
Hongshuai Liu, Chuangchuang Zhang, Jiadi Xu, Jing Jin, Liam Cheng, Qian Wu, Zhiliang Wei, Peiying Liu, Hanzhang Lu, Peter C. M. van Zijl, Christopher A. Ross, Jun Hua, Wenzhen Duan
bioRxiv 2020.11.17.386631; doi: https://doi.org/10.1101/2020.11.17.386631
HTT silencing delays onset and slows progression of Huntington’s disease like phenotype: Monitoring with a novel neurovascular biomarker
Hongshuai Liu, Chuangchuang Zhang, Jiadi Xu, Jing Jin, Liam Cheng, Qian Wu, Zhiliang Wei, Peiying Liu, Hanzhang Lu, Peter C. M. van Zijl, Christopher A. Ross, Jun Hua, Wenzhen Duan
bioRxiv 2020.11.17.386631; doi: https://doi.org/10.1101/2020.11.17.386631
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