Unscheduled origin building in S-phase upon tight CDK1 inhibition suppresses CFS instability

Olivier Brison; Stefano Gnan; Dana Azar; Mélanie Schmidt; Stéphane Koundrioukoff; Sami El-Hilali; Yan Jaszczyszyn; Anne-Marie Lachages; Claude Thermes; Chun-Long Chen; Michelle Debatisse

doi:10.1101/2020.11.19.390054

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Unscheduled origin building in S-phase upon tight CDK1 inhibition suppresses CFS instability

Olivier Brison, View ORCID ProfileStefano Gnan, Dana Azar, Mélanie Schmidt, Stéphane Koundrioukoff, Sami El-Hilali, Yan Jaszczyszyn, Anne-Marie Lachages, Claude Thermes, View ORCID ProfileChun-Long Chen, View ORCID ProfileMichelle Debatisse

doi: https://doi.org/10.1101/2020.11.19.390054

Olivier Brison

1CNRS UMR 9019, Gustave Roussy Institute, F-94805, Villejuif, France

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Stefano Gnan

2Curie Institute, PSL Research University, CNRS UMR 3244, F-75005, Paris, France

3Sorbonne University, F-75005 Paris, France

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ORCID record for Stefano Gnan

Dana Azar

2Curie Institute, PSL Research University, CNRS UMR 3244, F-75005, Paris, France

6Laboratoire Biodiversité et Génomique Fonctionnelle, Faculté des Sciences, Université Saint-Joseph, 1107 2050 Beirut, Lebanon

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Mélanie Schmidt

1CNRS UMR 9019, Gustave Roussy Institute, F-94805, Villejuif, France

5Paris-Saclay University, F-91198, Gif-sur-Yvette, France

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Stéphane Koundrioukoff

1CNRS UMR 9019, Gustave Roussy Institute, F-94805, Villejuif, France

3Sorbonne University, F-75005 Paris, France

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Sami El-Hilali

2Curie Institute, PSL Research University, CNRS UMR 3244, F-75005, Paris, France

3Sorbonne University, F-75005 Paris, France

7Villefranche sur mer Developmental Biology Laboratory, CNRS UMR7009, F-06234 Villefranche-sur-Mer, France

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Yan Jaszczyszyn

4Institute for Integrative Biology of the Cell (I2BC), UMR 9198CNRS, CEA, Paris-Sud University, F-91198, Gif-sur-Yvette, France

5Paris-Saclay University, F-91198, Gif-sur-Yvette, France

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Anne-Marie Lachages

2Curie Institute, PSL Research University, CNRS UMR 3244, F-75005, Paris, France

8UTCBS, CNRS UMR 8258/ INSERM U 1267, Sorbonne-Paris-Cité University, F-75006 Paris, France

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Claude Thermes

4Institute for Integrative Biology of the Cell (I2BC), UMR 9198CNRS, CEA, Paris-Sud University, F-91198, Gif-sur-Yvette, France

5Paris-Saclay University, F-91198, Gif-sur-Yvette, France

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Chun-Long Chen

2Curie Institute, PSL Research University, CNRS UMR 3244, F-75005, Paris, France

3Sorbonne University, F-75005 Paris, France

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ORCID record for Chun-Long Chen

Michelle Debatisse

1CNRS UMR 9019, Gustave Roussy Institute, F-94805, Villejuif, France

3Sorbonne University, F-75005 Paris, France

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ORCID record for Michelle Debatisse
For correspondence: michelle.debatisse@gustaveroussy.fr

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Posted November 20, 2020.

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Unscheduled origin building in S-phase upon tight CDK1 inhibition suppresses CFS instability

Olivier Brison, Stefano Gnan, Dana Azar, Mélanie Schmidt, Stéphane Koundrioukoff, Sami El-Hilali, Yan Jaszczyszyn, Anne-Marie Lachages, Claude Thermes, Chun-Long Chen, Michelle Debatisse

bioRxiv 2020.11.19.390054; doi: https://doi.org/10.1101/2020.11.19.390054

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Unscheduled origin building in S-phase upon tight CDK1 inhibition suppresses CFS instability

Olivier Brison, Stefano Gnan, Dana Azar, Mélanie Schmidt, Stéphane Koundrioukoff, Sami El-Hilali, Yan Jaszczyszyn, Anne-Marie Lachages, Claude Thermes, Chun-Long Chen, Michelle Debatisse

bioRxiv 2020.11.19.390054; doi: https://doi.org/10.1101/2020.11.19.390054

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