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History
- November 22, 2020.
Copyright
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.
Author Information
- Akiko Ogawa1,2,3,
- Chisae Nagiri4,13,
- Wataru Shihoya4,13,
- Asuka Inoue5,6,7,13,
- Kouki Kawakami5,
- Suzune Hiratsuka5,
- Junken Aoki7,8,
- Yasuhiro Ito3,
- Takeo Suzuki9,
- Tsutomu Suzuki9,
- Toshihiro Inoue3,
- Osamu Nureki4,
- Hidenobu Tanihara10,
- Kazuhito Tomizawa2,11 and
- Fan-Yan Wei1,2,12,14,*
- 1Department of Modomics Biology & Medicine, Institute of Development, Aging and Cancer (IDAC), Tohoku University, Sendai 980-8575, Japan
- 2Department of Molecular Physiology, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8556, Japan
- 3Department of Ophthalmology, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8556, Japan
- 4Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo 113-0033, Japan
- 5Laboratory of Molecular and Cellular Biochemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-8578, Japan
- 6Advanced Research & Development Programs for Medical Innovation (PRIME), Japan Agency for Medical Research and Development (AMED), Tokyo 100-0004, Japan
- 7Advanced Research & Development Programs for Medical Innovation (LEAP), AMED, Tokyo 100-0004, Japan
- 8Department of Health Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo 113-0033, Japan
- 9Department of Chemistry and Biotechnology, Graduate School of Engineering, University of Tokyo, Tokyo 113-8656, Japan
- 10Kumamoto University Hospital, Kumamoto 860-8556, Japan
- 11Center for Metabolic Regulation of Healthy Aging, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8556, Japan
- 12Precursory Research for Embryonic Science and Technology (PRESTO), Japan Science and Technology Agency (JST), Kawaguchi 332-0012, Japan
- ↵*Correspondence: fanyan.wei.d3{at}tohoku.ac.jp
↵13 These authors contributed equally to this study: Chisae Nagiri, Wataru Shihoya, and Asuka Inoue.