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Crystal structure of prototype foamy virus (PFV) protease-reverse transcriptase fusion (PR-RT) reveals conformational plasticity: implications for function
View ORCID ProfileJerry Joe E. K. Harrison, Steve Tuske, View ORCID ProfileKalyan Das, View ORCID ProfileFrancesc X. Ruiz, Joseph D. Bauman, Paul Boyer, Jeffrey J. DeStefano, Stephen H. Hughes, View ORCID ProfileEddy Arnold
doi: https://doi.org/10.1101/2020.11.23.395087
Jerry Joe E. K. Harrison
1Center for Advanced Biotechnology and Medicine (CABM), NJ, USA
3Department of Chemistry, University of Ghana, Legon, Ghana
Steve Tuske
1Center for Advanced Biotechnology and Medicine (CABM), NJ, USA
5Amicus Therapeutics, Gene Therapy Center of Excellence, 3675 Market Street, Philadelphia, PA, USA
Kalyan Das
1Center for Advanced Biotechnology and Medicine (CABM), NJ, USA
6Rega Institute and Department of Microbiology and Immunology, KU Leuven, Belgium
Francesc X. Ruiz
1Center for Advanced Biotechnology and Medicine (CABM), NJ, USA
Joseph D. Bauman
1Center for Advanced Biotechnology and Medicine (CABM), NJ, USA
5Amicus Therapeutics, Gene Therapy Center of Excellence, 3675 Market Street, Philadelphia, PA, USA
Paul Boyer
4National Cancer Institute, Drug Resistance Program, Frederick, MD, USA
Jeffrey J. DeStefano
7Department of Cell Biology and Molecular Genetics, University of Maryland College Park, College Park, MD, USA
Stephen H. Hughes
4National Cancer Institute, Drug Resistance Program, Frederick, MD, USA
Eddy Arnold
1Center for Advanced Biotechnology and Medicine (CABM), NJ, USA
2Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, NJ, USA
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Posted November 24, 2020.
Crystal structure of prototype foamy virus (PFV) protease-reverse transcriptase fusion (PR-RT) reveals conformational plasticity: implications for function
Jerry Joe E. K. Harrison, Steve Tuske, Kalyan Das, Francesc X. Ruiz, Joseph D. Bauman, Paul Boyer, Jeffrey J. DeStefano, Stephen H. Hughes, Eddy Arnold
bioRxiv 2020.11.23.395087; doi: https://doi.org/10.1101/2020.11.23.395087
Crystal structure of prototype foamy virus (PFV) protease-reverse transcriptase fusion (PR-RT) reveals conformational plasticity: implications for function
Jerry Joe E. K. Harrison, Steve Tuske, Kalyan Das, Francesc X. Ruiz, Joseph D. Bauman, Paul Boyer, Jeffrey J. DeStefano, Stephen H. Hughes, Eddy Arnold
bioRxiv 2020.11.23.395087; doi: https://doi.org/10.1101/2020.11.23.395087
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