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The Dutch Microbiome Project defines factors that shape the healthy gut microbiome
View ORCID ProfileR. Gacesa, View ORCID ProfileA. Kurilshikov, View ORCID ProfileA. Vich Vila, View ORCID ProfileT. Sinha, M.A.Y. Klaassen, View ORCID ProfileL.A. Bolte, View ORCID ProfileS. Andreu-Sánchez, View ORCID ProfileL. Chen, View ORCID ProfileV. Collij, S. Hu, J.A.M. Dekens, View ORCID ProfileV.C. Lenters, View ORCID ProfileJ.R. Björk, View ORCID ProfileJ.C. Swarte, View ORCID ProfileM.A. Swertz, B.H. Jansen, J. Gelderloos-Arends, Lifelines cohort study, M. Hofker, View ORCID ProfileR.C.H. Vermeulen, View ORCID ProfileS. Sanna, View ORCID ProfileH.J.M. Harmsen, View ORCID ProfileC. Wijmenga, View ORCID ProfileJ. Fu, View ORCID ProfileA. Zhernakova, View ORCID ProfileR.K. Weersma
doi: https://doi.org/10.1101/2020.11.27.401125
R. Gacesa
1University of Groningen and University Medical Center Groningen, Department of Gastroenterology and Hepatology, Groningen, the Netherlands
2University of Groningen and University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands
A. Kurilshikov
2University of Groningen and University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands
A. Vich Vila
1University of Groningen and University Medical Center Groningen, Department of Gastroenterology and Hepatology, Groningen, the Netherlands
2University of Groningen and University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands
T. Sinha
2University of Groningen and University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands
M.A.Y. Klaassen
1University of Groningen and University Medical Center Groningen, Department of Gastroenterology and Hepatology, Groningen, the Netherlands
2University of Groningen and University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands
L.A. Bolte
1University of Groningen and University Medical Center Groningen, Department of Gastroenterology and Hepatology, Groningen, the Netherlands
2University of Groningen and University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands
S. Andreu-Sánchez
2University of Groningen and University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands
3Department of Pediatrics, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands
L. Chen
2University of Groningen and University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands
3Department of Pediatrics, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands
V. Collij
1University of Groningen and University Medical Center Groningen, Department of Gastroenterology and Hepatology, Groningen, the Netherlands
2University of Groningen and University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands
S. Hu
1University of Groningen and University Medical Center Groningen, Department of Gastroenterology and Hepatology, Groningen, the Netherlands
2University of Groningen and University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands
J.A.M. Dekens
2University of Groningen and University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands
4University Medical Center Groningen, Center for Development and Innovation
V.C. Lenters
5University Medical Centre Utrecht, Julius Center for Health Sciences and Primary Care, 3584 CG Utrecht, The Netherlands
J.R. Björk
1University of Groningen and University Medical Center Groningen, Department of Gastroenterology and Hepatology, Groningen, the Netherlands
2University of Groningen and University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands
J.C. Swarte
1University of Groningen and University Medical Center Groningen, Department of Gastroenterology and Hepatology, Groningen, the Netherlands
2University of Groningen and University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands
M.A. Swertz
2University of Groningen and University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands
6University of Groningen and University Medical Center Groningen, Genomics Coordination Center, Groningen, The Netherlands
B.H. Jansen
1University of Groningen and University Medical Center Groningen, Department of Gastroenterology and Hepatology, Groningen, the Netherlands
2University of Groningen and University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands
J. Gelderloos-Arends
2University of Groningen and University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands
M. Hofker
3Department of Pediatrics, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands
R.C.H. Vermeulen
5University Medical Centre Utrecht, Julius Center for Health Sciences and Primary Care, 3584 CG Utrecht, The Netherlands
7Utrecht University, Institute for Risk Assessment Sciences (IRAS), Department of Population Health Sciences, 3584 CM Utrecht, The Netherlands
S. Sanna
2University of Groningen and University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands
8Institute for Genetic and Biomedical Research (IRGB), National Research Council (CNR), Cagliari, Italy
H.J.M. Harmsen
9Department of Medical Microbiology and Infection prevention: University of Groningen and University Medical Center Groningen, Groningen, The Netherlands
C. Wijmenga
2University of Groningen and University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands
J. Fu
2University of Groningen and University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands
3Department of Pediatrics, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands
A. Zhernakova
2University of Groningen and University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands
R.K. Weersma
1University of Groningen and University Medical Center Groningen, Department of Gastroenterology and Hepatology, Groningen, the Netherlands

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The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-ND 4.0 International license.
Posted November 27, 2020.
The Dutch Microbiome Project defines factors that shape the healthy gut microbiome
R. Gacesa, A. Kurilshikov, A. Vich Vila, T. Sinha, M.A.Y. Klaassen, L.A. Bolte, S. Andreu-Sánchez, L. Chen, V. Collij, S. Hu, J.A.M. Dekens, V.C. Lenters, J.R. Björk, J.C. Swarte, M.A. Swertz, B.H. Jansen, J. Gelderloos-Arends, Lifelines cohort study, M. Hofker, R.C.H. Vermeulen, S. Sanna, H.J.M. Harmsen, C. Wijmenga, J. Fu, A. Zhernakova, R.K. Weersma
bioRxiv 2020.11.27.401125; doi: https://doi.org/10.1101/2020.11.27.401125
The Dutch Microbiome Project defines factors that shape the healthy gut microbiome
R. Gacesa, A. Kurilshikov, A. Vich Vila, T. Sinha, M.A.Y. Klaassen, L.A. Bolte, S. Andreu-Sánchez, L. Chen, V. Collij, S. Hu, J.A.M. Dekens, V.C. Lenters, J.R. Björk, J.C. Swarte, M.A. Swertz, B.H. Jansen, J. Gelderloos-Arends, Lifelines cohort study, M. Hofker, R.C.H. Vermeulen, S. Sanna, H.J.M. Harmsen, C. Wijmenga, J. Fu, A. Zhernakova, R.K. Weersma
bioRxiv 2020.11.27.401125; doi: https://doi.org/10.1101/2020.11.27.401125
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