New Results
Single Cell and Spatial Transcriptomics Defines the Cellular Architecture of the Antimicrobial Response Network in Human Leprosy Granulomas
Feiyang Ma, Travis K. Hughes, Rosane M.B. Teles, Priscila R. Andrade, Bruno J. de Andrade Silva, Olesya Plazyo, Lam C. Tsoi, Tran Do, Marc H Wadsworth II, Aislyn Oulee, Maria Teresa Ochoa, Euzenir N. Sarno, M. Luisa Iruela-Arispe, Bryan Bryson, Alex K. Shalek, Barry R. Bloom, Johann E. Gudjonsson, Matteo Pellegrini, Robert L. Modlin
doi: https://doi.org/10.1101/2020.12.01.406819
Feiyang Ma
1Division of Dermatology, Department of Medicine, University of California, Los Angeles, CA 90095, USA
2Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, CA 90095, USA
3Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, CA 90095, USA
Travis K. Hughes
4Institute for Medical Engineering & Science (IMES) and Department of Chemistry, MIT, Cambridge, Massachusetts, USA
5Department of Immunology, Harvard Medical School, Boston, MA 02115, USA
6Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
7Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, USA
Rosane M.B. Teles
1Division of Dermatology, Department of Medicine, University of California, Los Angeles, CA 90095, USA
Priscila R. Andrade
1Division of Dermatology, Department of Medicine, University of California, Los Angeles, CA 90095, USA
Bruno J. de Andrade Silva
1Division of Dermatology, Department of Medicine, University of California, Los Angeles, CA 90095, USA
Olesya Plazyo
8Department of Dermatology, University of Michigan, Ann Arbor, Michigan, USA
Lam C. Tsoi
8Department of Dermatology, University of Michigan, Ann Arbor, Michigan, USA
Tran Do
1Division of Dermatology, Department of Medicine, University of California, Los Angeles, CA 90095, USA
Marc H Wadsworth II
4Institute for Medical Engineering & Science (IMES) and Department of Chemistry, MIT, Cambridge, Massachusetts, USA
6Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
7Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, USA
Aislyn Oulee
1Division of Dermatology, Department of Medicine, University of California, Los Angeles, CA 90095, USA
Maria Teresa Ochoa
9Department of Dermatology, University of Southern California, Los Angeles, CA, USA
Euzenir N. Sarno
10Leprosy Laboratory, Oswaldo Cruz Foundation, Rio de Janeiro, RJ, Brazil
M. Luisa Iruela-Arispe
11Department of Cell and Developmental Biology, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA
Bryan Bryson
7Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, USA
12Department of Biological Engineering, MIT, Cambridge, MA 02139, USA
Alex K. Shalek
4Institute for Medical Engineering & Science (IMES) and Department of Chemistry, MIT, Cambridge, Massachusetts, USA
5Department of Immunology, Harvard Medical School, Boston, MA 02115, USA
6Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
7Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, USA
Barry R. Bloom
13Harvard T.H. Chan School of Public Health, Department of Immunology and Infectious Diseases, Boston, MA, USA
Johann E. Gudjonsson
8Department of Dermatology, University of Michigan, Ann Arbor, Michigan, USA
Matteo Pellegrini
3Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, CA 90095, USA
Robert L. Modlin
1Division of Dermatology, Department of Medicine, University of California, Los Angeles, CA 90095, USA
2Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, CA 90095, USA
Posted December 02, 2020.
Single Cell and Spatial Transcriptomics Defines the Cellular Architecture of the Antimicrobial Response Network in Human Leprosy Granulomas
Feiyang Ma, Travis K. Hughes, Rosane M.B. Teles, Priscila R. Andrade, Bruno J. de Andrade Silva, Olesya Plazyo, Lam C. Tsoi, Tran Do, Marc H Wadsworth II, Aislyn Oulee, Maria Teresa Ochoa, Euzenir N. Sarno, M. Luisa Iruela-Arispe, Bryan Bryson, Alex K. Shalek, Barry R. Bloom, Johann E. Gudjonsson, Matteo Pellegrini, Robert L. Modlin
bioRxiv 2020.12.01.406819; doi: https://doi.org/10.1101/2020.12.01.406819
Single Cell and Spatial Transcriptomics Defines the Cellular Architecture of the Antimicrobial Response Network in Human Leprosy Granulomas
Feiyang Ma, Travis K. Hughes, Rosane M.B. Teles, Priscila R. Andrade, Bruno J. de Andrade Silva, Olesya Plazyo, Lam C. Tsoi, Tran Do, Marc H Wadsworth II, Aislyn Oulee, Maria Teresa Ochoa, Euzenir N. Sarno, M. Luisa Iruela-Arispe, Bryan Bryson, Alex K. Shalek, Barry R. Bloom, Johann E. Gudjonsson, Matteo Pellegrini, Robert L. Modlin
bioRxiv 2020.12.01.406819; doi: https://doi.org/10.1101/2020.12.01.406819
Subject Area
Subject Areas
- Biochemistry (11752)
- Bioengineering (8752)
- Bioinformatics (29200)
- Biophysics (14974)
- Cancer Biology (12096)
- Cell Biology (17411)
- Clinical Trials (138)
- Developmental Biology (9421)
- Ecology (14182)
- Epidemiology (2067)
- Evolutionary Biology (18308)
- Genetics (12245)
- Genomics (16803)
- Immunology (11869)
- Microbiology (28097)
- Molecular Biology (11594)
- Neuroscience (60969)
- Paleontology (451)
- Pathology (1871)
- Pharmacology and Toxicology (3238)
- Physiology (4959)
- Plant Biology (10427)
- Synthetic Biology (2886)
- Systems Biology (7340)
- Zoology (1651)