Skip to main content
bioRxiv
  • Home
  • About
  • Submit
  • ALERTS / RSS
Advanced Search
New Results

Multiple lineages of Streptomyces produce antimicrobials within passalid beetle galleries across eastern North America

View ORCID ProfileRita de Cassia Pessotti, View ORCID ProfileBridget L. Hansen, Jewel N. Reaso, Javier A. Ceja-Navarro, Laila El-Hifnawi, View ORCID ProfileEoin L. Brodie, View ORCID ProfileMatthew F. Traxler
doi: https://doi.org/10.1101/2020.12.02.394189
Rita de Cassia Pessotti
aDepartment of Plant and Microbial Biology, University of California, Berkeley, CA, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Rita de Cassia Pessotti
Bridget L. Hansen
aDepartment of Plant and Microbial Biology, University of California, Berkeley, CA, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Bridget L. Hansen
Jewel N. Reaso
aDepartment of Plant and Microbial Biology, University of California, Berkeley, CA, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Javier A. Ceja-Navarro
cBioengineering and Biomedical Sciences Department, Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA
dInstitute for Biodiversity Science and Sustainability, California Academy of Sciences, Berkeley, CA, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Laila El-Hifnawi
bDepartment of Molecular and Cellular Biology, University of California, Berkeley, CA, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Eoin L. Brodie
eEcology Department, Earth and Environmental Sciences, Lawrence Berkeley National Laboratory, Berkeley, CA, USA
fDepartment of Environmental Science, Policy and Management, University of California, Berkeley, CA, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Eoin L. Brodie
Matthew F. Traxler
aDepartment of Plant and Microbial Biology, University of California, Berkeley, CA, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Matthew F. Traxler
  • For correspondence: mtrax@berkeley.edu
  • Abstract
  • Full Text
  • Info/History
  • Metrics
  • Supplementary material
  • Preview PDF
Loading

ABSTRACT

Some insects form symbioses in which actinomycetes provide defense against pathogens by making antimicrobials. The range of chemical strategies employed across these associations, and how these strategies relate to insect lifestyle, remains underexplored. We assessed subsocial passalid beetles of the species Odontotaenius disjunctus, and their frass (fecal material) which is an important food resource within their galleries, as a model insect/actinomycete system. Through chemical and phylogenetic analyses, we found that O. disjunctus frass collected across eastern North America harbored multiple lineages of Streptomyces and diverse antimicrobials. Metabolites detected in frass displayed synergistic and antagonistic inhibition of a fungal entomopathogen, Metarhizium anisopliae, and multiple streptomycete isolates inhibited this pathogen when co-cultivated directly in frass. These findings support a model in which the lifestyle of O. disjunctus accommodates multiple Streptomyces lineages in their frass, resulting in a rich repertoire of antimicrobials that likely insulates their galleries against pathogenic invasion.

Competing Interest Statement

The authors have declared no competing interest.

Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY 4.0 International license.
Back to top
PreviousNext
Posted March 23, 2021.
Download PDF

Supplementary Material

Email

Thank you for your interest in spreading the word about bioRxiv.

NOTE: Your email address is requested solely to identify you as the sender of this article.

Enter multiple addresses on separate lines or separate them with commas.
Multiple lineages of Streptomyces produce antimicrobials within passalid beetle galleries across eastern North America
(Your Name) has forwarded a page to you from bioRxiv
(Your Name) thought you would like to see this page from the bioRxiv website.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Share
Multiple lineages of Streptomyces produce antimicrobials within passalid beetle galleries across eastern North America
Rita de Cassia Pessotti, Bridget L. Hansen, Jewel N. Reaso, Javier A. Ceja-Navarro, Laila El-Hifnawi, Eoin L. Brodie, Matthew F. Traxler
bioRxiv 2020.12.02.394189; doi: https://doi.org/10.1101/2020.12.02.394189
Reddit logo Twitter logo Facebook logo LinkedIn logo Mendeley logo
Citation Tools
Multiple lineages of Streptomyces produce antimicrobials within passalid beetle galleries across eastern North America
Rita de Cassia Pessotti, Bridget L. Hansen, Jewel N. Reaso, Javier A. Ceja-Navarro, Laila El-Hifnawi, Eoin L. Brodie, Matthew F. Traxler
bioRxiv 2020.12.02.394189; doi: https://doi.org/10.1101/2020.12.02.394189

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Subject Area

  • Microbiology
Subject Areas
All Articles
  • Animal Behavior and Cognition (4373)
  • Biochemistry (9561)
  • Bioengineering (7075)
  • Bioinformatics (24800)
  • Biophysics (12581)
  • Cancer Biology (9929)
  • Cell Biology (14306)
  • Clinical Trials (138)
  • Developmental Biology (7938)
  • Ecology (12085)
  • Epidemiology (2067)
  • Evolutionary Biology (15965)
  • Genetics (10910)
  • Genomics (14716)
  • Immunology (9850)
  • Microbiology (23597)
  • Molecular Biology (9463)
  • Neuroscience (50757)
  • Paleontology (369)
  • Pathology (1537)
  • Pharmacology and Toxicology (2675)
  • Physiology (4003)
  • Plant Biology (8646)
  • Scientific Communication and Education (1506)
  • Synthetic Biology (2388)
  • Systems Biology (6417)
  • Zoology (1345)