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The linkage of methionine addiction, overmethylation of histone H3 lysines and malignancy demonstrated when cancer cells revert to methionine-independence
View ORCID ProfileJun Yamamoto, Sachiko Inubushi, Qinghong Han, Yoshihiko Tashiro, Norihiko Sugisawa, Kazuyuki Hamada, Yusuke Aoki, Kentaro Miyake, Ryusei Matsuyama, Michael Bouvet, Steven G. Clarke, Itaru Endo, Robert M. Hoffman
doi: https://doi.org/10.1101/2020.12.04.412437
Jun Yamamoto
1AntiCancer Inc, 7917 Ostrow St, San Diego, CA, 92111, USA
2Department of Surgery, University of California, San Diego, 9300 Campus Point Drive #7220, La Jolla, CA, 92037-7220, USA
3Department of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan
Sachiko Inubushi
1AntiCancer Inc, 7917 Ostrow St, San Diego, CA, 92111, USA
2Department of Surgery, University of California, San Diego, 9300 Campus Point Drive #7220, La Jolla, CA, 92037-7220, USA
Qinghong Han
1AntiCancer Inc, 7917 Ostrow St, San Diego, CA, 92111, USA
Yoshihiko Tashiro
1AntiCancer Inc, 7917 Ostrow St, San Diego, CA, 92111, USA
2Department of Surgery, University of California, San Diego, 9300 Campus Point Drive #7220, La Jolla, CA, 92037-7220, USA
Norihiko Sugisawa
1AntiCancer Inc, 7917 Ostrow St, San Diego, CA, 92111, USA
2Department of Surgery, University of California, San Diego, 9300 Campus Point Drive #7220, La Jolla, CA, 92037-7220, USA
Kazuyuki Hamada
1AntiCancer Inc, 7917 Ostrow St, San Diego, CA, 92111, USA
2Department of Surgery, University of California, San Diego, 9300 Campus Point Drive #7220, La Jolla, CA, 92037-7220, USA
Yusuke Aoki
1AntiCancer Inc, 7917 Ostrow St, San Diego, CA, 92111, USA
2Department of Surgery, University of California, San Diego, 9300 Campus Point Drive #7220, La Jolla, CA, 92037-7220, USA
Kentaro Miyake
3Department of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan
Ryusei Matsuyama
3Department of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan
Michael Bouvet
2Department of Surgery, University of California, San Diego, 9300 Campus Point Drive #7220, La Jolla, CA, 92037-7220, USA
Steven G. Clarke
4Department of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, CA, 90095-1569, USA
Itaru Endo
3Department of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan
Robert M. Hoffman
1AntiCancer Inc, 7917 Ostrow St, San Diego, CA, 92111, USA
2Department of Surgery, University of California, San Diego, 9300 Campus Point Drive #7220, La Jolla, CA, 92037-7220, USA
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Posted August 03, 2021.
The linkage of methionine addiction, overmethylation of histone H3 lysines and malignancy demonstrated when cancer cells revert to methionine-independence
Jun Yamamoto, Sachiko Inubushi, Qinghong Han, Yoshihiko Tashiro, Norihiko Sugisawa, Kazuyuki Hamada, Yusuke Aoki, Kentaro Miyake, Ryusei Matsuyama, Michael Bouvet, Steven G. Clarke, Itaru Endo, Robert M. Hoffman
bioRxiv 2020.12.04.412437; doi: https://doi.org/10.1101/2020.12.04.412437
The linkage of methionine addiction, overmethylation of histone H3 lysines and malignancy demonstrated when cancer cells revert to methionine-independence
Jun Yamamoto, Sachiko Inubushi, Qinghong Han, Yoshihiko Tashiro, Norihiko Sugisawa, Kazuyuki Hamada, Yusuke Aoki, Kentaro Miyake, Ryusei Matsuyama, Michael Bouvet, Steven G. Clarke, Itaru Endo, Robert M. Hoffman
bioRxiv 2020.12.04.412437; doi: https://doi.org/10.1101/2020.12.04.412437
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