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Anti-SARS-CoV-2 activity of Andrographis paniculata extract and its major component Andrographolide in human lung epithelial cells and cytotoxicity evaluation in major organ cell representatives
Khanit Sa-ngiamsuntorn, Ampa Suksatu, Yongyut Pewkliang, Piyanoot Thongsri, Phongthon Kanjanasirirat, Suwimon Manopwisedjaroen, Sitthivut Charoensutthivarakul, Patompon Wongtrakoongate, Supaporn Pitiporn, Phisit Khemawoot, Somchai Chutipongtanate, Suparerk Borwornpinyo, Arunee Thitithanyanont, Suradej Hongeng
doi: https://doi.org/10.1101/2020.12.08.415836
Khanit Sa-ngiamsuntorn
1Department of Biochemistry, Faculty of Pharmacy, Mahidol University, Bangkok 10400, Thailand
Ampa Suksatu
2Department of Microbiology, Faculty of Science, Mahidol University, Bangkok 10400 Thailand
Yongyut Pewkliang
3Section for Translational Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand
Piyanoot Thongsri
3Section for Translational Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand
Phongthon Kanjanasirirat
4Excellent Center for Drug Discovery (ECDD), Faculty of Science, Mahidol University, Bangkok, 10400, Thailand
Suwimon Manopwisedjaroen
2Department of Microbiology, Faculty of Science, Mahidol University, Bangkok 10400 Thailand
Sitthivut Charoensutthivarakul
4Excellent Center for Drug Discovery (ECDD), Faculty of Science, Mahidol University, Bangkok, 10400, Thailand
5School of Bioinnovation and Bio-Based Product Intelligence, Faculty of Science, Mahidol University, Bangkok 10400, Thailand
6Center for Neuroscience, Faculty of Science, Mahidol University, Bangkok 10400, Thailand
Patompon Wongtrakoongate
6Center for Neuroscience, Faculty of Science, Mahidol University, Bangkok 10400, Thailand
7Department of Biochemistry, Faculty of Science, Mahidol University, Bangkok 10400, Thailand
Supaporn Pitiporn
8ChaoPhya Abhaibhubejhr Hospital, Prachin Buri 25000, Thailand
Phisit Khemawoot
9Chakri Naruebodindra Medical Institute, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Samutprakarn 10540 Thailand
Somchai Chutipongtanate
9Chakri Naruebodindra Medical Institute, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Samutprakarn 10540 Thailand
10Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand
Suparerk Borwornpinyo
4Excellent Center for Drug Discovery (ECDD), Faculty of Science, Mahidol University, Bangkok, 10400, Thailand
11Department of Biotechnology, Faculty of Science, Mahidol University, Bangkok 10400, Thailand
Arunee Thitithanyanont
2Department of Microbiology, Faculty of Science, Mahidol University, Bangkok 10400 Thailand
Suradej Hongeng
4Excellent Center for Drug Discovery (ECDD), Faculty of Science, Mahidol University, Bangkok, 10400, Thailand
10Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand
Posted December 08, 2020.
Anti-SARS-CoV-2 activity of Andrographis paniculata extract and its major component Andrographolide in human lung epithelial cells and cytotoxicity evaluation in major organ cell representatives
Khanit Sa-ngiamsuntorn, Ampa Suksatu, Yongyut Pewkliang, Piyanoot Thongsri, Phongthon Kanjanasirirat, Suwimon Manopwisedjaroen, Sitthivut Charoensutthivarakul, Patompon Wongtrakoongate, Supaporn Pitiporn, Phisit Khemawoot, Somchai Chutipongtanate, Suparerk Borwornpinyo, Arunee Thitithanyanont, Suradej Hongeng
bioRxiv 2020.12.08.415836; doi: https://doi.org/10.1101/2020.12.08.415836
Anti-SARS-CoV-2 activity of Andrographis paniculata extract and its major component Andrographolide in human lung epithelial cells and cytotoxicity evaluation in major organ cell representatives
Khanit Sa-ngiamsuntorn, Ampa Suksatu, Yongyut Pewkliang, Piyanoot Thongsri, Phongthon Kanjanasirirat, Suwimon Manopwisedjaroen, Sitthivut Charoensutthivarakul, Patompon Wongtrakoongate, Supaporn Pitiporn, Phisit Khemawoot, Somchai Chutipongtanate, Suparerk Borwornpinyo, Arunee Thitithanyanont, Suradej Hongeng
bioRxiv 2020.12.08.415836; doi: https://doi.org/10.1101/2020.12.08.415836
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