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Millisecond-scale molecular dynamics simulation of spike RBD structure reveals evolutionary adaption of SARS-CoV-2 to stably bind ACE2

Gard Nelson, Oleksandr Buzko, Aaron Bassett, Patricia Spilman, Kayvan Niazi, Shahrooz Rabizadeh, View ORCID ProfilePatrick Soon-Shiong
doi: https://doi.org/10.1101/2020.12.11.422055
Gard Nelson
1ImmunityBio, LLC. 9920 Jefferson Blvd., Culver City, CA 90232, USA
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  • For correspondence: gard.nelson@immunitybio.com
Oleksandr Buzko
1ImmunityBio, LLC. 9920 Jefferson Blvd., Culver City, CA 90232, USA
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Aaron Bassett
2NantHealth, Inc. 2040 E. Mariposa Ave., El Segundo, CA 90245
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Patricia Spilman
1ImmunityBio, LLC. 9920 Jefferson Blvd., Culver City, CA 90232, USA
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Kayvan Niazi
1ImmunityBio, LLC. 9920 Jefferson Blvd., Culver City, CA 90232, USA
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Shahrooz Rabizadeh
1ImmunityBio, LLC. 9920 Jefferson Blvd., Culver City, CA 90232, USA
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Patrick Soon-Shiong
1ImmunityBio, LLC. 9920 Jefferson Blvd., Culver City, CA 90232, USA
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  • ORCID record for Patrick Soon-Shiong
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Article Information

doi 
https://doi.org/10.1101/2020.12.11.422055
History 
  • December 12, 2020.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Gard Nelson1,*,
  2. Oleksandr Buzko1,
  3. Aaron Bassett2,
  4. Patricia Spilman1,
  5. Kayvan Niazi1,
  6. Shahrooz Rabizadeh1 and
  7. Patrick Soon-Shiong1
  1. 1ImmunityBio, LLC. 9920 Jefferson Blvd., Culver City, CA 90232, USA
  2. 2NantHealth, Inc. 2040 E. Mariposa Ave., El Segundo, CA 90245
  1. ↵*Correspondence to: Gard Nelson gard.nelson{at}immunitybio.com
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Posted December 12, 2020.
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Millisecond-scale molecular dynamics simulation of spike RBD structure reveals evolutionary adaption of SARS-CoV-2 to stably bind ACE2
Gard Nelson, Oleksandr Buzko, Aaron Bassett, Patricia Spilman, Kayvan Niazi, Shahrooz Rabizadeh, Patrick Soon-Shiong
bioRxiv 2020.12.11.422055; doi: https://doi.org/10.1101/2020.12.11.422055
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Millisecond-scale molecular dynamics simulation of spike RBD structure reveals evolutionary adaption of SARS-CoV-2 to stably bind ACE2
Gard Nelson, Oleksandr Buzko, Aaron Bassett, Patricia Spilman, Kayvan Niazi, Shahrooz Rabizadeh, Patrick Soon-Shiong
bioRxiv 2020.12.11.422055; doi: https://doi.org/10.1101/2020.12.11.422055

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