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Cancer-Associated Mutations Perturb the Structure and Interactions of the Intrinsically Disordered p53 Transactivation Domain

Lynn G. Schrag, Indhujah Thevarajan, Xiaorong Liu, Om Prakash, Michal Zolkiewski, Jianhan Chen
doi: https://doi.org/10.1101/2020.12.12.422504
Lynn G. Schrag
1Department of Biochemistry and Molecular Biophysics, Kansas State University, Manhattan, KS 66505, USA
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Indhujah Thevarajan
1Department of Biochemistry and Molecular Biophysics, Kansas State University, Manhattan, KS 66505, USA
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Xiaorong Liu
2Department of Chemistry, University of Massachusetts Amherst, Amherst, MA 01003, USA
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Om Prakash
1Department of Biochemistry and Molecular Biophysics, Kansas State University, Manhattan, KS 66505, USA
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  • For correspondence: omp@ksu.edu michalz@ksu.edu jianhanc@umass.edu
Michal Zolkiewski
1Department of Biochemistry and Molecular Biophysics, Kansas State University, Manhattan, KS 66505, USA
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  • For correspondence: omp@ksu.edu michalz@ksu.edu jianhanc@umass.edu
Jianhan Chen
2Department of Chemistry, University of Massachusetts Amherst, Amherst, MA 01003, USA
3Department of Biochemistry and Molecular Biology, University of Massachusetts Amherst, Amherst, MA 01003, USA
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  • For correspondence: omp@ksu.edu michalz@ksu.edu jianhanc@umass.edu
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Posted December 12, 2020.
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Cancer-Associated Mutations Perturb the Structure and Interactions of the Intrinsically Disordered p53 Transactivation Domain
Lynn G. Schrag, Indhujah Thevarajan, Xiaorong Liu, Om Prakash, Michal Zolkiewski, Jianhan Chen
bioRxiv 2020.12.12.422504; doi: https://doi.org/10.1101/2020.12.12.422504
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Cancer-Associated Mutations Perturb the Structure and Interactions of the Intrinsically Disordered p53 Transactivation Domain
Lynn G. Schrag, Indhujah Thevarajan, Xiaorong Liu, Om Prakash, Michal Zolkiewski, Jianhan Chen
bioRxiv 2020.12.12.422504; doi: https://doi.org/10.1101/2020.12.12.422504

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