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Wild-type FUS corrects ALS-like disease induced by cytoplasmic mutant FUS through autoregulation
Inmaculada Sanjuan-Ruiz, Noé Govea-Perez, Melissa Mcalonis-Downes, Stéphane Dieterle, Salim Megat, Sylvie Dirrig-Grosch, Gina Picchiarelli, Diana Piol, Qiang Zhu, Brian Myers, Chao-Zong Lee, Don W Cleveland, Clotilde Lagier-Tourenne, Sandrine Da Cruz, Luc Dupuis
doi: https://doi.org/10.1101/2020.12.16.423060
Inmaculada Sanjuan-Ruiz
1Université de Strasbourg, Inserm, Mécanismes centraux et périphériques de la neurodégénérescence, UMR-S1118, Centre de Recherches en Biomédecine, Strasbourg, France
Noé Govea-Perez
2Ludwig Institute for Cancer Research, University of California San Diego, La Jolla, USA
Melissa Mcalonis-Downes
2Ludwig Institute for Cancer Research, University of California San Diego, La Jolla, USA
Stéphane Dieterle
1Université de Strasbourg, Inserm, Mécanismes centraux et périphériques de la neurodégénérescence, UMR-S1118, Centre de Recherches en Biomédecine, Strasbourg, France
Salim Megat
1Université de Strasbourg, Inserm, Mécanismes centraux et périphériques de la neurodégénérescence, UMR-S1118, Centre de Recherches en Biomédecine, Strasbourg, France
Sylvie Dirrig-Grosch
1Université de Strasbourg, Inserm, Mécanismes centraux et périphériques de la neurodégénérescence, UMR-S1118, Centre de Recherches en Biomédecine, Strasbourg, France
Gina Picchiarelli
1Université de Strasbourg, Inserm, Mécanismes centraux et périphériques de la neurodégénérescence, UMR-S1118, Centre de Recherches en Biomédecine, Strasbourg, France
Diana Piol
3VIB-KU Leuven Center for Brain and Disease Research and Department of Neurosciences, KU Leuven, Leuven, Belgium
Qiang Zhu
2Ludwig Institute for Cancer Research, University of California San Diego, La Jolla, USA
Brian Myers
2Ludwig Institute for Cancer Research, University of California San Diego, La Jolla, USA
Chao-Zong Lee
4Department of Neurology, The Sean M. Healey and AMG Center for ALS at Mass General, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
5Broad Institute of Harvard University and MIT, Cambridge, MA, USA
Don W Cleveland
2Ludwig Institute for Cancer Research, University of California San Diego, La Jolla, USA
Clotilde Lagier-Tourenne
4Department of Neurology, The Sean M. Healey and AMG Center for ALS at Mass General, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
5Broad Institute of Harvard University and MIT, Cambridge, MA, USA
Sandrine Da Cruz
2Ludwig Institute for Cancer Research, University of California San Diego, La Jolla, USA
3VIB-KU Leuven Center for Brain and Disease Research and Department of Neurosciences, KU Leuven, Leuven, Belgium
Luc Dupuis
1Université de Strasbourg, Inserm, Mécanismes centraux et périphériques de la neurodégénérescence, UMR-S1118, Centre de Recherches en Biomédecine, Strasbourg, France
Posted December 16, 2020.
Wild-type FUS corrects ALS-like disease induced by cytoplasmic mutant FUS through autoregulation
Inmaculada Sanjuan-Ruiz, Noé Govea-Perez, Melissa Mcalonis-Downes, Stéphane Dieterle, Salim Megat, Sylvie Dirrig-Grosch, Gina Picchiarelli, Diana Piol, Qiang Zhu, Brian Myers, Chao-Zong Lee, Don W Cleveland, Clotilde Lagier-Tourenne, Sandrine Da Cruz, Luc Dupuis
bioRxiv 2020.12.16.423060; doi: https://doi.org/10.1101/2020.12.16.423060
Wild-type FUS corrects ALS-like disease induced by cytoplasmic mutant FUS through autoregulation
Inmaculada Sanjuan-Ruiz, Noé Govea-Perez, Melissa Mcalonis-Downes, Stéphane Dieterle, Salim Megat, Sylvie Dirrig-Grosch, Gina Picchiarelli, Diana Piol, Qiang Zhu, Brian Myers, Chao-Zong Lee, Don W Cleveland, Clotilde Lagier-Tourenne, Sandrine Da Cruz, Luc Dupuis
bioRxiv 2020.12.16.423060; doi: https://doi.org/10.1101/2020.12.16.423060
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