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The SARS-CoV-2 spike protein disrupts the cooperative function of human cardiac pericytes - endothelial cells through CD147 receptor-mediated signalling: a potential non-infective mechanism of COVID-19 microvascular disease

View ORCID ProfileElisa Avolio, Monica Gamez, Kapil Gupta, Rebecca Foster, Imre Berger, Massimo Caputo, Andrew Davidson, Darryl Hill, Paolo Madeddu
doi: https://doi.org/10.1101/2020.12.21.423721
Elisa Avolio
1Bristol Medical School, Translational Health Sciences, University of Bristol, Bristol, United Kingdom
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  • ORCID record for Elisa Avolio
  • For correspondence: elisa.avolio@bristol.ac.uk mdprm@bristol.ac.uk
Monica Gamez
1Bristol Medical School, Translational Health Sciences, University of Bristol, Bristol, United Kingdom
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Kapil Gupta
2School of Biochemistry, University of Bristol, Bristol, United Kingdom
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Rebecca Foster
1Bristol Medical School, Translational Health Sciences, University of Bristol, Bristol, United Kingdom
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Imre Berger
2School of Biochemistry, University of Bristol, Bristol, United Kingdom
3Max Planck Bristol Centre for Minimal Biology, University of Bristol, Bristol, United Kingdom
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Massimo Caputo
1Bristol Medical School, Translational Health Sciences, University of Bristol, Bristol, United Kingdom
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Andrew Davidson
4School of Cellular and Molecular Medicine, University of Bristol, Bristol, United Kingdom
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Darryl Hill
4School of Cellular and Molecular Medicine, University of Bristol, Bristol, United Kingdom
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Paolo Madeddu
1Bristol Medical School, Translational Health Sciences, University of Bristol, Bristol, United Kingdom
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  • For correspondence: elisa.avolio@bristol.ac.uk mdprm@bristol.ac.uk
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Posted December 21, 2020.
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The SARS-CoV-2 spike protein disrupts the cooperative function of human cardiac pericytes - endothelial cells through CD147 receptor-mediated signalling: a potential non-infective mechanism of COVID-19 microvascular disease
Elisa Avolio, Monica Gamez, Kapil Gupta, Rebecca Foster, Imre Berger, Massimo Caputo, Andrew Davidson, Darryl Hill, Paolo Madeddu
bioRxiv 2020.12.21.423721; doi: https://doi.org/10.1101/2020.12.21.423721
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The SARS-CoV-2 spike protein disrupts the cooperative function of human cardiac pericytes - endothelial cells through CD147 receptor-mediated signalling: a potential non-infective mechanism of COVID-19 microvascular disease
Elisa Avolio, Monica Gamez, Kapil Gupta, Rebecca Foster, Imre Berger, Massimo Caputo, Andrew Davidson, Darryl Hill, Paolo Madeddu
bioRxiv 2020.12.21.423721; doi: https://doi.org/10.1101/2020.12.21.423721

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