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Hidden paths to endless forms most wonderful: Parasite-blind diversification of host quality

View ORCID ProfileLisa Freund, Marie Vasse, Gregory J. Velicer
doi: https://doi.org/10.1101/2020.12.23.424158
Lisa Freund
Institute for Integrative Biology, ETH Zürich, 8092 Zürich, Switzerland
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  • For correspondence: lisa.freund@env.ethz.ch
Marie Vasse
Institute for Integrative Biology, ETH Zürich, 8092 Zürich, Switzerland
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Gregory J. Velicer
Institute for Integrative Biology, ETH Zürich, 8092 Zürich, Switzerland
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Abstract

Evolutionary diversification can occur in allopatry or sympatry, can be unselected or driven by selection, and can be phenotypically manifested immediately or remain phenotypically latent until later manifestation in a newly encountered environment. Diversification of host-parasite interactions is frequently studied in the context of intrinsically selective coevolution, but the potential for host-parasite interaction phenotypes to diversify latently during parasite-blind evolution is rarely considered. Here we use a social bacterium experimentally adapted to several environments in the absence of phage to analyse allopatric diversification of latent host quality - the degree to which a host population supports a viral epidemic. Phage-blind evolution reduced host quality overall, with some bacteria becoming completely resistant to growth suppression by phage. Selective-environment differences generated only mild divergence in host-quality. However, selective environments nonetheless played a major role in shaping evolution by determining the degree of stochastic diversification among replicate populations within treatments. Ancestral motility genotype was also found to strongly shape patterns of latent hostquality evolution and diversification. These outcomes show that adaptive landscapes can differ in how they constrain stochastic diversification of a latent phenotype and that major effects of selection on biological diversification can be missed by focusing on trait means. Collectively, our findings suggest that latent-phenotype evolution (LPE) should inform host-parasite evolution theory and that diversification should be conceived broadly to include latent phenotypes.

Competing Interest Statement

The authors have declared no competing interest.

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The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.
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Posted December 23, 2020.
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Hidden paths to endless forms most wonderful: Parasite-blind diversification of host quality
Lisa Freund, Marie Vasse, Gregory J. Velicer
bioRxiv 2020.12.23.424158; doi: https://doi.org/10.1101/2020.12.23.424158
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Hidden paths to endless forms most wonderful: Parasite-blind diversification of host quality
Lisa Freund, Marie Vasse, Gregory J. Velicer
bioRxiv 2020.12.23.424158; doi: https://doi.org/10.1101/2020.12.23.424158

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