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Berberine and obatoclax inhibit SARS-CoV-2 replication in primary human nasal epithelial cells in vitro
View ORCID ProfileFinny S. Varghese, View ORCID ProfileEsther van Woudenbergh, View ORCID ProfileGijs J. Overheul, View ORCID ProfileMarc J. Eleveld, Lisa Kurver, Niels van Heerbeek, View ORCID ProfileArjan van Laarhoven, View ORCID ProfilePascal Miesen, View ORCID ProfileGerco den Hartog, View ORCID ProfileMarien I. de Jonge, View ORCID ProfileRonald P. van Rij
doi: https://doi.org/10.1101/2020.12.23.424189
Finny S. Varghese
1Department of Medical Microbiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands
Esther van Woudenbergh
2Section Paediatric Infectious Diseases, Laboratory of Medical Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands
3Centre for Immunology of Infectious Diseases and Vaccines, National Institute for Public Health and the Environment, Bilthoven, The Netherlands
Gijs J. Overheul
1Department of Medical Microbiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands
Marc J. Eleveld
2Section Paediatric Infectious Diseases, Laboratory of Medical Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands
Lisa Kurver
4Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands
Niels van Heerbeek
5Department of Otolaryngology, Head and Neck Surgery, Radboudumc, Nijmegen, The Netherlands
Arjan van Laarhoven
4Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands
Pascal Miesen
1Department of Medical Microbiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands
Gerco den Hartog
3Centre for Immunology of Infectious Diseases and Vaccines, National Institute for Public Health and the Environment, Bilthoven, The Netherlands
Marien I. de Jonge
2Section Paediatric Infectious Diseases, Laboratory of Medical Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands
Ronald P. van Rij
1Department of Medical Microbiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands
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Posted December 24, 2020.
Berberine and obatoclax inhibit SARS-CoV-2 replication in primary human nasal epithelial cells in vitro
Finny S. Varghese, Esther van Woudenbergh, Gijs J. Overheul, Marc J. Eleveld, Lisa Kurver, Niels van Heerbeek, Arjan van Laarhoven, Pascal Miesen, Gerco den Hartog, Marien I. de Jonge, Ronald P. van Rij
bioRxiv 2020.12.23.424189; doi: https://doi.org/10.1101/2020.12.23.424189
Berberine and obatoclax inhibit SARS-CoV-2 replication in primary human nasal epithelial cells in vitro
Finny S. Varghese, Esther van Woudenbergh, Gijs J. Overheul, Marc J. Eleveld, Lisa Kurver, Niels van Heerbeek, Arjan van Laarhoven, Pascal Miesen, Gerco den Hartog, Marien I. de Jonge, Ronald P. van Rij
bioRxiv 2020.12.23.424189; doi: https://doi.org/10.1101/2020.12.23.424189
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