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Remdesivir-ivermectin combination displays synergistic interaction with improved in vitro antiviral activity against SARS-CoV-2
Laura N Jeffreys, Shaun H Pennington, Jack Duggan, Claire H Caygill, Rose C Lopeman, Alastair F Breen, Jessica B Jinks, Alison Ardrey, Samantha Donnellan, View ORCID ProfileEdward I Patterson, View ORCID ProfileGrant L Hughes, David W Hong, Paul M O’Neill, Ghaith Aljayyoussi, Andrew Owen, View ORCID ProfileStephen A Ward, View ORCID ProfileGiancarlo A Biagini
doi: https://doi.org/10.1101/2020.12.23.424232
Laura N Jeffreys
1Centre for Drugs and Diagnostics, Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, L3 5QA, UK
Shaun H Pennington
1Centre for Drugs and Diagnostics, Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, L3 5QA, UK
Jack Duggan
1Centre for Drugs and Diagnostics, Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, L3 5QA, UK
Claire H Caygill
Rose C Lopeman
Alastair F Breen
1Centre for Drugs and Diagnostics, Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, L3 5QA, UK
Jessica B Jinks
1Centre for Drugs and Diagnostics, Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, L3 5QA, UK
Alison Ardrey
1Centre for Drugs and Diagnostics, Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, L3 5QA, UK
Samantha Donnellan
1Centre for Drugs and Diagnostics, Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, L3 5QA, UK
Edward I Patterson
1Centre for Drugs and Diagnostics, Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, L3 5QA, UK
2Department of Vector Biology, Liverpool School of Tropical Medicine, Liverpool, L3 5QA, UK
Grant L Hughes
1Centre for Drugs and Diagnostics, Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, L3 5QA, UK
2Department of Vector Biology, Liverpool School of Tropical Medicine, Liverpool, L3 5QA, UK
David W Hong
3Department of Chemistry, University of Liverpool, Liverpool, L69 7ZD, U.K
Paul M O’Neill
3Department of Chemistry, University of Liverpool, Liverpool, L69 7ZD, U.K
Ghaith Aljayyoussi
1Centre for Drugs and Diagnostics, Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, L3 5QA, UK
Andrew Owen
4Department of Pharmacology and Therapeutics, Centre of Excellence in Long-acting Therapeutics (CELT), University of Liverpool, Liverpool, L69 3GE, UK
Stephen A Ward
1Centre for Drugs and Diagnostics, Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, L3 5QA, UK
Giancarlo A Biagini
1Centre for Drugs and Diagnostics, Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, L3 5QA, UK
Article usage
Posted September 01, 2021.
Remdesivir-ivermectin combination displays synergistic interaction with improved in vitro antiviral activity against SARS-CoV-2
Laura N Jeffreys, Shaun H Pennington, Jack Duggan, Claire H Caygill, Rose C Lopeman, Alastair F Breen, Jessica B Jinks, Alison Ardrey, Samantha Donnellan, Edward I Patterson, Grant L Hughes, David W Hong, Paul M O’Neill, Ghaith Aljayyoussi, Andrew Owen, Stephen A Ward, Giancarlo A Biagini
bioRxiv 2020.12.23.424232; doi: https://doi.org/10.1101/2020.12.23.424232
Remdesivir-ivermectin combination displays synergistic interaction with improved in vitro antiviral activity against SARS-CoV-2
Laura N Jeffreys, Shaun H Pennington, Jack Duggan, Claire H Caygill, Rose C Lopeman, Alastair F Breen, Jessica B Jinks, Alison Ardrey, Samantha Donnellan, Edward I Patterson, Grant L Hughes, David W Hong, Paul M O’Neill, Ghaith Aljayyoussi, Andrew Owen, Stephen A Ward, Giancarlo A Biagini
bioRxiv 2020.12.23.424232; doi: https://doi.org/10.1101/2020.12.23.424232
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