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Genetic epidemiology of variants associated with immune escape from global SARS-CoV-2 genomes
View ORCID ProfileBani Jolly, View ORCID ProfileMercy Rophina, Afra Shamnath, View ORCID ProfileMohamed Imran, View ORCID ProfileRahul C. Bhoyar, View ORCID ProfileMohit Kumar Divakar, Pallavali Roja Rani, View ORCID ProfileGyan Ranjan, View ORCID ProfileParas Sehgal, Pulala Chandrasekhar, S. Afsar, J. Vijaya Lakshmi, A. Surekha, View ORCID ProfileSridhar Sivasubbu, View ORCID ProfileVinod Scaria
doi: https://doi.org/10.1101/2020.12.24.424332
Bani Jolly
1CSIR-Institute of Genomics and Integrative Biology (CSIR-IGIB), New Delhi, India
2Academy of Scientific and Innovative Research (AcSIR), CSIR-HRDC Ghaziabad, Uttar Pradesh, India
Mercy Rophina
1CSIR-Institute of Genomics and Integrative Biology (CSIR-IGIB), New Delhi, India
2Academy of Scientific and Innovative Research (AcSIR), CSIR-HRDC Ghaziabad, Uttar Pradesh, India
Afra Shamnath
1CSIR-Institute of Genomics and Integrative Biology (CSIR-IGIB), New Delhi, India
Mohamed Imran
1CSIR-Institute of Genomics and Integrative Biology (CSIR-IGIB), New Delhi, India
2Academy of Scientific and Innovative Research (AcSIR), CSIR-HRDC Ghaziabad, Uttar Pradesh, India
Rahul C. Bhoyar
1CSIR-Institute of Genomics and Integrative Biology (CSIR-IGIB), New Delhi, India
Mohit Kumar Divakar
1CSIR-Institute of Genomics and Integrative Biology (CSIR-IGIB), New Delhi, India
2Academy of Scientific and Innovative Research (AcSIR), CSIR-HRDC Ghaziabad, Uttar Pradesh, India
Pallavali Roja Rani
3Kurnool Medical College, Kurnool, Andhra Pradesh, India
Gyan Ranjan
1CSIR-Institute of Genomics and Integrative Biology (CSIR-IGIB), New Delhi, India
2Academy of Scientific and Innovative Research (AcSIR), CSIR-HRDC Ghaziabad, Uttar Pradesh, India
Paras Sehgal
1CSIR-Institute of Genomics and Integrative Biology (CSIR-IGIB), New Delhi, India
2Academy of Scientific and Innovative Research (AcSIR), CSIR-HRDC Ghaziabad, Uttar Pradesh, India
Pulala Chandrasekhar
3Kurnool Medical College, Kurnool, Andhra Pradesh, India
S. Afsar
3Kurnool Medical College, Kurnool, Andhra Pradesh, India
J. Vijaya Lakshmi
3Kurnool Medical College, Kurnool, Andhra Pradesh, India
A. Surekha
3Kurnool Medical College, Kurnool, Andhra Pradesh, India
Sridhar Sivasubbu
1CSIR-Institute of Genomics and Integrative Biology (CSIR-IGIB), New Delhi, India
2Academy of Scientific and Innovative Research (AcSIR), CSIR-HRDC Ghaziabad, Uttar Pradesh, India
Vinod Scaria
1CSIR-Institute of Genomics and Integrative Biology (CSIR-IGIB), New Delhi, India
2Academy of Scientific and Innovative Research (AcSIR), CSIR-HRDC Ghaziabad, Uttar Pradesh, India

Abstract
Many antibody and immune escape variants in SARS-CoV-2 are now documented in literature. The availability of SARS-CoV-2 genome sequences enabled us to investigate the occurrence and genetic epidemiology of the variants globally. Our analysis suggests that a number of genetic variants associated with immune escape have emerged in global populations.
Competing Interest Statement
The authors have declared no competing interest.
Footnotes
Author name and Affiliation updated.
Copyright
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.
Posted January 05, 2021.
Genetic epidemiology of variants associated with immune escape from global SARS-CoV-2 genomes
Bani Jolly, Mercy Rophina, Afra Shamnath, Mohamed Imran, Rahul C. Bhoyar, Mohit Kumar Divakar, Pallavali Roja Rani, Gyan Ranjan, Paras Sehgal, Pulala Chandrasekhar, S. Afsar, J. Vijaya Lakshmi, A. Surekha, Sridhar Sivasubbu, Vinod Scaria
bioRxiv 2020.12.24.424332; doi: https://doi.org/10.1101/2020.12.24.424332
Genetic epidemiology of variants associated with immune escape from global SARS-CoV-2 genomes
Bani Jolly, Mercy Rophina, Afra Shamnath, Mohamed Imran, Rahul C. Bhoyar, Mohit Kumar Divakar, Pallavali Roja Rani, Gyan Ranjan, Paras Sehgal, Pulala Chandrasekhar, S. Afsar, J. Vijaya Lakshmi, A. Surekha, Sridhar Sivasubbu, Vinod Scaria
bioRxiv 2020.12.24.424332; doi: https://doi.org/10.1101/2020.12.24.424332
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