A computational model for investigating the evolution of colonic crypts during Lynch syndrome carcinogenesis

Saskia Haupt; Nils Gleim; Aysel Ahadova; Hendrik Bläker; Magnus von Knebel Doeberitz; Matthias Kloor; Vincent Heuveline

doi:10.1101/2020.12.29.424555

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A computational model for investigating the evolution of colonic crypts during Lynch syndrome carcinogenesis

View ORCID ProfileSaskia Haupt, View ORCID ProfileNils Gleim, View ORCID ProfileAysel Ahadova, View ORCID ProfileHendrik Bläker, View ORCID ProfileMagnus von Knebel Doeberitz, View ORCID ProfileMatthias Kloor, View ORCID ProfileVincent Heuveline

doi: https://doi.org/10.1101/2020.12.29.424555

Saskia Haupt

1Engineering Mathematics and Computing Lab (EMCL), Interdisciplinary Center for Scientific Computing (IWR), Heidelberg University, Heidelberg, Germany

2Data Mining and Uncertainty Quantification (DMQ), Heidelberg Institute for Theoretical Studies (HITS), Heidelberg, Germany

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ORCID record for Saskia Haupt
For correspondence: saskia.haupt@uni-heidelberg.de

Nils Gleim

1Engineering Mathematics and Computing Lab (EMCL), Interdisciplinary Center for Scientific Computing (IWR), Heidelberg University, Heidelberg, Germany

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Aysel Ahadova

3Department of Applied Tumor Biology (ATB), Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany

4Clinical Cooperation Unit Applied Tumor Biology, German Cancer Research Center, Heidelberg, Germany

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Hendrik Bläker

5Institute of Pathology, University Hospital Leipzig, Leipzig, Germany

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Magnus von Knebel Doeberitz

3Department of Applied Tumor Biology (ATB), Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany

4Clinical Cooperation Unit Applied Tumor Biology, German Cancer Research Center, Heidelberg, Germany

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Matthias Kloor

3Department of Applied Tumor Biology (ATB), Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany

4Clinical Cooperation Unit Applied Tumor Biology, German Cancer Research Center, Heidelberg, Germany

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Vincent Heuveline

1Engineering Mathematics and Computing Lab (EMCL), Interdisciplinary Center for Scientific Computing (IWR), Heidelberg University, Heidelberg, Germany

2Data Mining and Uncertainty Quantification (DMQ), Heidelberg Institute for Theoretical Studies (HITS), Heidelberg, Germany

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A computational model for investigating the evolution of colonic crypts during Lynch syndrome carcinogenesis

Saskia Haupt, Nils Gleim, Aysel Ahadova, Hendrik Bläker, Magnus von Knebel Doeberitz, Matthias Kloor, Vincent Heuveline

bioRxiv 2020.12.29.424555; doi: https://doi.org/10.1101/2020.12.29.424555

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A computational model for investigating the evolution of colonic crypts during Lynch syndrome carcinogenesis

Saskia Haupt, Nils Gleim, Aysel Ahadova, Hendrik Bläker, Magnus von Knebel Doeberitz, Matthias Kloor, Vincent Heuveline

bioRxiv 2020.12.29.424555; doi: https://doi.org/10.1101/2020.12.29.424555

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