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A computational model for investigating the evolution of colonic crypts during Lynch syndrome carcinogenesis

View ORCID ProfileSaskia Haupt, View ORCID ProfileNils Gleim, View ORCID ProfileAysel Ahadova, View ORCID ProfileHendrik Bläker, View ORCID ProfileMagnus von Knebel Doeberitz, View ORCID ProfileMatthias Kloor, View ORCID ProfileVincent Heuveline
doi: https://doi.org/10.1101/2020.12.29.424555
Saskia Haupt
1Engineering Mathematics and Computing Lab (EMCL), Interdisciplinary Center for Scientific Computing (IWR), Heidelberg University, Heidelberg, Germany
2Data Mining and Uncertainty Quantification (DMQ), Heidelberg Institute for Theoretical Studies (HITS), Heidelberg, Germany
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  • ORCID record for Saskia Haupt
  • For correspondence: saskia.haupt@uni-heidelberg.de
Nils Gleim
1Engineering Mathematics and Computing Lab (EMCL), Interdisciplinary Center for Scientific Computing (IWR), Heidelberg University, Heidelberg, Germany
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  • ORCID record for Nils Gleim
Aysel Ahadova
3Department of Applied Tumor Biology (ATB), Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany
4Clinical Cooperation Unit Applied Tumor Biology, German Cancer Research Center, Heidelberg, Germany
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Hendrik Bläker
5Institute of Pathology, University Hospital Leipzig, Leipzig, Germany
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Magnus von Knebel Doeberitz
3Department of Applied Tumor Biology (ATB), Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany
4Clinical Cooperation Unit Applied Tumor Biology, German Cancer Research Center, Heidelberg, Germany
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Matthias Kloor
3Department of Applied Tumor Biology (ATB), Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany
4Clinical Cooperation Unit Applied Tumor Biology, German Cancer Research Center, Heidelberg, Germany
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Vincent Heuveline
1Engineering Mathematics and Computing Lab (EMCL), Interdisciplinary Center for Scientific Computing (IWR), Heidelberg University, Heidelberg, Germany
2Data Mining and Uncertainty Quantification (DMQ), Heidelberg Institute for Theoretical Studies (HITS), Heidelberg, Germany
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Article Information

doi 
https://doi.org/10.1101/2020.12.29.424555
History 
  • July 6, 2021.

Article Versions

  • Version 1 (December 29, 2020 - 20:50).
  • You are viewing Version 2, the most recent version of this article.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Saskia Haupt1,2,*,
  2. Nils Gleim1,
  3. Aysel Ahadova3,4,
  4. Hendrik Bläker5,
  5. Magnus von Knebel Doeberitz3,4,
  6. Matthias Kloor3,4 and
  7. Vincent Heuveline1,2
  1. 1Engineering Mathematics and Computing Lab (EMCL), Interdisciplinary Center for Scientific Computing (IWR), Heidelberg University, Heidelberg, Germany
  2. 2Data Mining and Uncertainty Quantification (DMQ), Heidelberg Institute for Theoretical Studies (HITS), Heidelberg, Germany
  3. 3Department of Applied Tumor Biology (ATB), Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany
  4. 4Clinical Cooperation Unit Applied Tumor Biology, German Cancer Research Center, Heidelberg, Germany
  5. 5Institute of Pathology, University Hospital Leipzig, Leipzig, Germany
  1. ↵*Correspondence
    Saskia Haupt, Engineering Mathematics and Computing Lab (EMCL), Interdisciplinary Center for Scientific Computing (IWR), Heidelberg University, Heidelberg, Germany, Email: saskia.haupt{at}uni-heidelberg.de
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Posted July 06, 2021.
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A computational model for investigating the evolution of colonic crypts during Lynch syndrome carcinogenesis
Saskia Haupt, Nils Gleim, Aysel Ahadova, Hendrik Bläker, Magnus von Knebel Doeberitz, Matthias Kloor, Vincent Heuveline
bioRxiv 2020.12.29.424555; doi: https://doi.org/10.1101/2020.12.29.424555
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A computational model for investigating the evolution of colonic crypts during Lynch syndrome carcinogenesis
Saskia Haupt, Nils Gleim, Aysel Ahadova, Hendrik Bläker, Magnus von Knebel Doeberitz, Matthias Kloor, Vincent Heuveline
bioRxiv 2020.12.29.424555; doi: https://doi.org/10.1101/2020.12.29.424555

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